Variation in the pattern of omissions and substitutions of grammatical morphemes in the spontaneous speech of so-called agrammatic patients

We describe the patterns of omissions (and substitutions) of freestanding grammatical morphemes and the patterns of substitutions of bound grammatical morphemes in 20 so-called agrammatic patients. Extreme variation was observed in the patterns of omissions and substitutions of grammatical morphemes, both in terms of the distribution of errors for different grammatical morphemes as well as in terms of the distribution of omissions versus substitutions. Results are discussed in the context of current debates concerning the possibility of a theoretically motivated distinction between the clinical categories of agrammatism and paragrammatism and, more generally, concerning the theoretical usefulness of any clinical category. The conclusion is reached that the observed heterogeneity in the production of grammatical morphemes among putatively agrammatic patients renders the clinical category of agrammatism, and by extension all other clinical categories from the classical classification scheme (e.g., Broca's aphasia, Wernicke's aphasia, and so forth) to more recent classificatory attempts (e.g., surface dyslexia, deep dysgraphia, and so forth), theoretically useless.     

The structure of graphemic representations

The analysis of the spelling performance of a brain-damaged dysgraphic subject is reported. The subject's spelling performance was affected by various graphotactic factors, such as the distinction between consonant and vowel and graphosyllabic structure. For example, while the subject produced many consonant and vowel deletion errors when these were part of consonant and vowel clusters, respectively (e.g., sfondo----sondo; giunta----gunta), deletions were virtually never produced for single consonants flanked by two vowels (e.g., onesto----oesto) or for single vowels flanked by two consonants (e.g., tirare----trare). The demonstration that graphosyllabic factors affect spelling performance disconfirms the hypothesis that graphemic representations consist simply of linearly ordered sets of graphemes. It is concluded that graphemic representations are multidimensional structures: one dimension specifies the grapheme identities that comprise the spelling of a word; a second dimension specifies the consonant/vowel status of the graphemes; a third dimension represents the graphosyllabic structure of the grapheme string; and, a fourth dimension provides information about geminate features.     

The Italian version of the Thinking About Life Experiences Questionnaire and its relationship with gender,age, and life events on Facebook

The present study provided a cross-cultural validation of the Thinking About Life Experiences Scale-revised (TALE-R) in an Italian sample of Facebook users (n = 492; female = 378; male = 114; mean age 26.1) to test for replication and universality of the TALE-R three-factor model. Furthermore, it explored the interrelations among gender, age, the scores at the TALE-R and the frequency of posting textual/visual information about individuals' life events on Facebook. Results at exploratory and confirmatory factor analysis gave empirical support to both of a tripartite model for the functions of autobiographical memory (i.e., directive-behavior, social-bonding, and self-continuity) and measurement invariance of this three-factor model across gender and age. Further results at linear correlation and regression analyses showed that directive-behavior and self-continuity functions of autobiographical memory are significantly related to the ways people use Facebook for personal documentation. Age differences more than gender influence this association. Discussion and conclusion reported both theoretical and empirical implications of the findings of the study.     

Further Distinctions between Coping and Defense Mechanisms?

In the current literature there is a great confusion between coping and defense mechanisms. As Cramer (1998) points out, a distinction between them is both possible and worthwhile in that they possess different cognitive features. Cramer proposes two basic criteria: the conscious/unconscious and the intentional/unintentional nature of the processes. We focus on a further criterion, the manipulation versus revision of one's mental attitudes, which so far has been neglected in the relevant literature. We suggest that responses to adversity implying manipulation are typical of defense mechanisms, while those implying the revision of one's mental attitudes characterize coping strategies. Finally, we address emotion-focused coping as the area where coping and defense meet, and we suggest that responses displaying defensive features should be excluded from the category of coping in accordance with the distinctions identified.     

The Effects of a Multiple Family Therapy on Adolescents with Eating Disorders: An Outcome Study

Multiple Family Therapy (MFT) has gained increasing popularity in the treatment of eating disorders and many programs have been developed over the past decade. Still, there is little evidence in the literature on the effectiveness on MFT for treating eating disorders. The present study examines the effects of a particular model of Multiple Family Therapy on eating disorder symptoms, quality of life, and percentage of Expected Body Weight (%EBW) in adolescents with eating disorders (ED). Eighty‐two adolescents with ED, aged between 11 and 19 years, were assessed before and after treatment using the Eating Disorders Inventory 2 (EDI‐2), the Outcome Questionnaire 45 (OQ‐45) and %EBW. Results showed a significant increase in %EBW between the beginning and end of treatment, with a large effect size. 52.4% of patients achieved an EBW above 85%. Symptoms relative to all EDI dimensions (except for bulimia) significantly decreased during treatment. The three dimensions related to quality of life assessment also improved over the course of MFT. At the end of treatment, 70.7% of patients had a total OQ‐45 score below clinical significance. This study suggests that Multiple Family Therapy may benefit adolescents with eating disorders, with improvement on several outcome measures (%EBW, ED symptoms, and quality of life). However, the lack of a comparison group entails caution when drawing conclusions.     

Language Mapping with Verbs and Sentences in Awake Surgery: A Review

Intraoperative language mapping in awake surgery is typically conducted by asking the patient to produce automatic speech and to name objects. These tasks might not map language with sufficient accuracy, as some linguistic processes can only be triggered by tasks that use verbs and sentences. Verb and sentence processing tasks are currently used during surgery, albeit sparsely. Medline, PubMed, and Web of Science records were searched to retrieve studies focused on language mapping with verbs/sentences in awake surgery. We review the tasks reported in the published literature, spell out the language processes assessed by each task, list the cortical and subcortical regions whose stimulation inhibited language processing, and consider the types of errors elicited by stimulation in each region. We argue that using verb tasks allows a more thorough evaluation of language functions. We also argue that verb tasks are preferable to object naming tasks in the case of frontal lesions, as lesion and neuroimaging data demonstrate that these regions play a critical role in verb and sentence processing. We discuss the clinical value of these tasks and the current limitations of the procedure, and provide some guidelines for their development. Future research should aim toward a differentiated approach to language mapping – one that includes the administration of standardized and customizable tests and the use of longitudinal neurocognitive follow-up studies. Further work will allow researchers and clinicians to understand brain and language correlates and to improve the current surgical practice.     

Impaired configural body processing in anorexia nervosa: Evidence from the body inversion effect

Patients with anorexia nervosa (AN) suffer from severe disturbances of body perception. It is unclear, however, whether such disturbances are linked to specific alterations in the processing of body configurations with respect to the local processing of body part details. Here, we compared a consecutive sample of 12 AN patients with a group of 12 age‐, gender‐ and education‐matched controls using an inversion effect paradigm requiring the visual discrimination of upright and inverted pictures of whole bodies, faces and objects. The AN patients presented selective deficits in the discrimination of upright body stimuli, which requires configural processing. Conversely, patients and controls showed comparable abilities in the discrimination of inverted bodies, which involves only detail‐based processing, and in the discrimination of both upright and inverted faces and objects. Importantly, the body inversion effect negatively correlated with the persistence scores at the Temperament and Character Inventory, which evaluates increased tendency to convert a signal of punishment into a signal of reinforcement. These results suggest that the deficits of configural processing in AN patients may be associated with their obsessive worries about body appearance and to the excessive attention to details that characterizes their general perceptual style.     

The role of Broca's area in speech perception: evidence from aphasia revisited

Motor theories of speech perception have been re-vitalized as a consequence of the discovery of mirror neurons. Some authors have even promoted a strong version of the motor theory, arguing that the motor speech system is critical for perception. Part of the evidence that is cited in favor of this claim is the observation from the early 1980s that individuals with Broca’s aphasia, and therefore inferred damage to Broca’s area, can have deficits in speech sound discrimination. Here we re-examine this issue in 24 patients with radiologically confirmed lesions to Broca’s area and various degrees of associated non-fluent speech production. Patients performed two same-different discrimination tasks involving pairs of CV syllables, one in which both CVs were presented auditorily, and the other in which one syllable was auditorily presented and the other visually presented as an orthographic form; word comprehension was also assessed using word-to-picture matching tasks in both auditory and visual forms. Discrimination performance on the all-auditory task was four standard deviations above chance, as measured using d′, and was unrelated to the degree of non-fluency in the patients’ speech production. Performance on the auditory–visual task, however, was worse than, and not correlated with, the all-auditory task. The auditory–visual task was related to the degree of speech non-fluency. Word comprehension was at ceiling for the auditory version (97% accuracy) and near ceiling for the orthographic version (90% accuracy). We conclude that the motor speech system is not necessary for speech perception as measured both by discrimination and comprehension paradigms, but may play a role in orthographic decoding or in auditory–visual matching of phonological forms.