床边教学法在医学伦理学教学中的探索与实践

在医学伦理学的教学实践中引入床边教学法,在激发学习兴趣、促进沟通技能、培养实践能力和提升综合素质等方面具有很大的优越性.积极探索床边教学的方法与效果,注意教学过程中存在的问题,整合优势资源,在整个医学体系中深入医学伦理观念,对于实践教学的未来发展具有重要意义.     

异种器官移植及其伦理问题

目前,开展的异种移植研究主要以猪为供体源,面临的主要障碍是宿主抗移植物的免疫排斥反应(超急性排斥、急性排斥和慢性排斥)和猪内源性反转录病毒感染,并已取得一定进展.但异种移植引发的伦理问题也不容忽视,主要有跨物种感染、卫生资源分配、动物的权利和人格同一性等问题.     

青少年社会认知复杂性与同伴交往的相关分析

社会认知复杂性是描述个体社会认知结构特点的个体差异变量,作为社会认知领域的研究热点,当前却鲜有研究关注它与同伴交往的关系。本研究选取初一至高二234名中学生考察了社会认知复杂性与同伴交往之间的关系,并辅以人际交往能力、学业成就通过结构方程模型进一步探讨了二者之间关联的路径。结果表明：（1）青少年社会认知复杂性与同伴接受、同伴拒绝、人际交往能力、学业成就之间存在显著相关。社会认知复杂性高的学生获得了较多的同伴接纳、较少的同伴拒绝,并具有较高的人际交往能力和学业成就。（2）青少年社会认知复杂性以人际交往能力和学业成就为中介变量间接影响同伴的受欢迎程度。     

Semantic size does not matter: "bigger" words are not recognized faster

Sereno, O'Donnell, and Sereno (2009) reported that words are recognized faster in a lexical decision task when their referents are physically large than when they are small, suggesting that "semantic size" might be an important variable that should be considered in visual word recognition research and modelling. We sought to replicate their size effect, but failed to find a significant latency advantage in lexical decision for "big" words (cf. "small" words), even though we used the same word stimuli as Sereno et al. and had almost three times as many subjects. We also examined existing data from visual word recognition megastudies (e.g., English Lexicon Project) and found that semantic size is not a significant predictor of lexical decision performance after controlling for the standard lexical variables. In summary, the null results from our lab experiment--despite a much larger subject sample size than Sereno et al.--converged with our analysis of megastudy lexical decision performance, leading us to conclude that semantic size does not matter for word recognition. Discussion focuses on why semantic size (unlike some other semantic variables) is unlikely to play a role in lexical decision.     

Tangible words are recognized faster: the grounding of meaning in sensory and perceptual systems

Sensory experience rating (SER), a new variable motivated by the grounded cognition framework of conceptual processing (e.g., Barsalou, 2008 ), indexes the degree to which a word evokes sensory/perceptual experiences. In the present study, SERs were collected for over 2,850 words. While SER is correlated with imageability, age of acquisition, and word frequency, the latter variables (along with seven others) account for less than 30% of the variance in SER. Reanalyses of two large-scale studies demonstrate that SER significantly predicts lexical decision times when other established predictor variables are statistically controlled. These results suggest that conceptual processing is grounded in sensory systems. Additionally, a major benefit of this variable is that it allows psycholinguistic researchers to examine semantic-perceptual links for all word classes with a single rating.     

赖氨酰氧化酶在动脉粥样硬化中的作用

赖氨酰氧化酶(lysyl oxidase,LOX)是一种铜依赖性氨基氧化酶,在多个组织器官中均有表达,能参与催化细胞外基质(extracellular matrix,ECM)中胶原和弹性纤维的赖氨酸残基交联,以维持细胞外基质的结构和功能正常。新近研究发现LOX与动脉粥样硬化亦有紧密关系。本文就LOX在动脉粥样硬化发生、发展过程中的联系作一综述。     

囊虫病诊断技术的发展与临床应用

囊虫病是一种由猪囊尾蚴寄生于人体组织内主要引起脑、眼等重要器官或组织损害的常见寄生虫病。目前对其诊断的实验技术研究已发展到高层水平,但被临床应用的并不多。本文从多个方面较全面地分析和回答了出现此现象的原因,并提出了拟解决临床问题的见解与探索思路。     

过度医疗的伦理学会诊及其治疗处方--兼论临床诊治最优化伦理准则

过度医疗是一个极其复杂的医学-社会问题,给予医学伦理学的解析是解决这一问题的最基本的工作。目前,服务质量虚高而服务收费真高是过度医疗的实质和特点;它貌似临床最优化服务,但却严重背离临床诊治最优化准则,对二者进行鉴别诊断是必要的、可能的;伦理学会诊的结论是：该病为疑难病综合征,由医者医学伦理素质低下、医院管理背弃伦理理念、医改政策中伦理机制缺席等多病因相互作用所致;所以,根治过度医疗的处方必须是全方位的、系列连续的、标本兼治的。