Ritanserin and voluntary alcohol intake in rats

In a previous study (Rammsayer & Vogel, 1991), rats selectively bred for high and low catecholamine responses to stress showed a selective response to the 5-HT2 receptor blocker ritanserin. However, it remained unclear whether selective breeding resulted in a decrease in 5-HT responsivity, as suggested by the lack of an effect in high stress responding rats, or in an increase in 5-HT responsivity, as suggested by ritanserin-induced reduction in alcohol intake in low-responding rats. To answer this question, nonselectively bred rats were forced to drink a 5% alcohol solution for 10 days. For the subsequent six days, animals were injected subcutaneously with 2.5 mg/kg/2 ml ritanserin or vehicle only, and both a 5% solution of alcohol and water were presented to the animals. Ritanserin neither affected alcohol nor total fluid intake suggesting that in the general population of N/NIH (Hansen) rats as well as in rats of the same strain selectively bred for high catecholamine responses, mesolimbic dopaminergic activity is not effectively modulated by specific blockade of 5-HT2 receptors. However, a very pronounced ritanserin induced difference in daily water intake between nonbred male and female rats became evident.     

Nonconsensual Sexual Experiences in Precollege Women: Prevalence and Risk Factors

The authors of this study examined the prevalence of nonconsensual sexual experiences in dating situations among a sample of 330 incoming female college students. Results indicated that 38.5% of women reported experiencing at least one form of sexual victimization in dating, ranging from unwanted sexual contact to rape. Victimization was related to history of childhood sexual abuse as well as previous consensual sexual activity. Discussion focuses on the need for education and prevention programs during the secondary school years and counseling assistance for college-age victims.     

Handgun Ownership and the Religion Factor

This article addresses the relationship between religious affiliation and a very specific form of firearms ownership, that is, handgun ownership. Literature is reviewed relative to explanations of gun ownership. A test of the hypothesized relationship between religious affiliation and handgun ownership demonstrated a statistically significant ( p < 0.03) association. Protestants were found to have a disproportionately high level of handgun ownership compared to other religious groups. Speculation for this finding is reviewed relative to other recent research on this topic.     

Change schools through revolution,not evolution

The school's traditional practices are linked to current failures and to the limited prospects of future success. The major problems with current school practices are: adopting instructional programs that have never been fieldtested and revised on the basis of data; using diagnostic practices that blame the child as being the sole cause of poor performance; using testing techniques that do not imply curricular remedies; promoting children beyond their grade-level performance; failing to provide teachers with effective training and monitoring. Recommendations for changing the system to become accountable and databased include: bringing pressure from outside the system; lobbying for alternatives to public schools; promoting intervention by the board; involving parents in union negotiations; establishing committees of expert teachers to review administrative proposals and report to the board. The central feature of the plan is to fire administrators who fail to meet attainable student-achievement goals. This practice would ensure that administrators are reinforced when children succeed, a feature that is not part of current practices.     

Differential effects of a 5-HT2 receptor blocker on alcohol intake in rats selectively bred for high and low catecholamine responses to stress

The effect of the selective 5-HT2 receptor blocker ritanserin on alcohol consumption was investigated in two strains of rats selectively bred for high and low catecholamine responses to stress. Rats were forced to drink a 5% alcohol solution for 10 days. For the subsequent six days, animals were injected subcutaneously with 2.5 mg/kg/2 ml ritanserin or vehicle only, and both a 5% solution of alcohol and water were presented to the animals. Ritanserin affected neither water nor total fluid intake. Furthermore, no effect of ritanserin on alcohol consumption could be demonstrated in high-responding rats, whereas in low-responding rats a very pronounced ritanserin-induced reduction in alcohol intake was observed. Results are discussed in terms of mediating effects of serotonergic neurons on mesolimbic dopaminergic reward systems related to drug addiction.     

Wissenschaftliche Prüfung und wissenschaftliche Anerkennung psychotherapeutischer Verfahren

The authors focus on the following questions: firstly, what anthropological preconceptions lie behind the nomological scientific viewpoints adopted by the scientific advisory board “psychotherapy”, secondly, to what extend a general efficacy of psychotherapy can be verified using the criteria it proposes. The authors demonstrate that in the proposed testing procedure humans are conceptualized as beings without consciousness and subjectivity. Furthermore, nomologically designed investigations cannot verify a general efficacy of new forms of psychotherapy, nor could they verify the general efficacy of those psychotherapeutic methods already approved by the insurance companies.     

The Relationship of Physiological Arousal with Demand and Withdraw Behavior: Examining the Accuracy of the Escape-Conditioning Hypothesis

The escape-conditioning model suggests that husbands experience greater physiological arousal during marital conflict than their wives. This greater arousal is hypothesized to lead to withdrawal from conflict in order to lessen the arousal. The present results, based on a U.S. sample of 64 heterosexual couples, found no support for this model. During problem-solving discussions, husbands did not exhibit greater skin conductance and did not report greater arousal than their wives. Furthermore, skin conductance was negatively linked to withdraw behavior. These results, while not consistent with the escape-conditioning model, are in line with recent studies that have explicitly examined gender differences in other types of physiological arousal during marital conflict.     

Perceptual expertise enhances the resolution but not the number of representations in working memory

Despite its central role in cognition, capacity in visual working memory is restricted to about three or four items. Curby and Gauthier (2007) examined whether perceptual expertise can help to overcome this limit by enabling more efficient coding of visual information. In line with this, they observed higher capacity estimates for upright than for inverted faces, suggesting that perceptual expertise enhances visual working memory. In the present work, we examined whether the improved capacity estimates for upright faces indicates an increased number of "slots" in working memory, or improved resolution within the existing slots. Our results suggest that perceptual expertise enhances the resolution but not the number of representations that can be held in working memory. These results clarify the effects of perceptual expertise in working memory and support recent suggestions that number and resolution represent distinct facets of working memory ability.