Intelligence and changes in regional cerebral glucose metabolic rate following learning

Positron emission tomography (PET) studies of brain glucose metabolic rate (GMR) in normal volunteers report inverse correlations between GMR and scores on the Raven's Advanced Progressive Matrices (RAPM) and verbal fluency. A new study in eight normal men reports widespread significant GMR decreases following learning a complex task (the computer game “Tetris”). The purpose of this study is to ascertain the correlations between GMR changes following learning “Tetris” and psychometric intelligence scores (RAPM and WAIS-R) to determine whether high-ability subjects show the largest GMR decreases, as predicted by a brain efficiency hypothesis. This hypothesis is supported with significant correlations between the magnitude of GMR change and intelligence scores in many brain areas that changed with learning. Some implications for the role of attention, memory, and speed of processing are discussed in view of the specific brain areas involved.     

An investigation of cognitive-behavior therapy combined with oral valium for children undergoing painful medical procedures

In previous research, a cognitive-behavioral therapy (CBT) package was found to be effective in reducing children's distress associated with the painful medical procedures of bone marrow aspirations (BMAs) and lumbar punctures (LPs). Orally administered Valium demonstrated less effectiveness but was helpful in reducing behavioral distress before the medical procedure. In the present study, we investigated whether the combination of oral Valium and CBT would result in increased efficacy of the CBT. Eighty-three subjects were randomly assigned to receive either CBT or CBT plus Valium while undergoing either a BMA or an LP. Dependent variables included observed behavioral distress, self-reported fear and pain, and pulse rate. Results failed to support the value of such a combination but did provide additional evidence in regard to the effectiveness of the CBT. The need for more potent medical interventions for some children is discussed.     

Anger and cardiovascular risk in adolescents

The present investigation examined the relationship between anger and elevations in cardiovascular risk among adolescents (n = 213). The adolescents were assessed on an anger index and also on certain physical (e.g., blood pressure, cholesterol) and psychological (e.g., anxiety, life dissatisfaction) variables associated with increased risk of cardiovascular diseases. The anger index, a composite of items from various sources, was factor analyzed, producing a terminal solution of two factors: frequent anger directed outward (FAO) and anger-producing situations (AS). Two factor scores were then computed for each subject. Regression analyses, controlling for age and sex, showed that the factor scores were predictive of the physical and psychological measures of cardiovascular risk, and that the factor scores were differentially related to these indices. These preliminary findings are supportive of systematic study both of the multidimensional nature of anger and of the associations of the dimensions of anger with indices of cardiovascular risk.     

Extinction of morphine analgesic tolerance

It has been suggested that the analgesic effect of morphine becomes attenuated over the course of successive administrations by a conditional, compensatory, hyperalgesic response elicited by the administration procedure, thus accounting (in part) for analgesic tolerance. On the basis of this associative model of tolerance, it would be predicted that established tolerance would be extinguished by placebo sessions. In experiments of apparently similar design (but conducted by different experimenters in different laboratories), data both confirming and refuting this prediction have previously been published. The present experiment, conducted jointly by the experimenters who reported the divergent findings, was designed to determine the reasons for the different results. It was found that placebo sessions do consistently attenuate morphine analgesic tolerance. Such extinction is not limited to the experimenter, drug preparation, rat strain, or apparatus used in the original, successful demonstration of the phenomenon, but rather is also demonstrable under conditions similar to those used in subsequent experiments which failed to demonstrate extinction of tolerance. Results of the present experiment suggest that the failures to demonstrate extinction of tolerance were attributable to insufficient extinction training.     

The role of predrug signals in morphine analgesic tolerance: support for a Pavlovian conditioning model of tolerance

According to a model of morphine tolerance, which emphasizes Pavlovian conditioning principles, tolerance results from an association between predrug environmental cues and the systemic effects of the drug. To assess this model, groups of rats were administered morphine on either three or nine occasions, with a complex environmental stimulus either paired or not paired with each injection. Control groups had equivalent experience with the environmental cue and injection procedure, but the injected substance was physiological saline. Subsequently, the analgesic effect of the opiate was tested in all subjects following administration of the drug in conjunction with the environmental cue. As expected on the basis of the conditioning model of tolerance, subjects with a pretest history of paired morphine administrations displayed analgesic tolerance, but subjects with a pretest history of unpaired administration displayed no evidence of such tolerance. The results suggest that prior demonstrations that the display of morphine tolerance is specific to the drug administration environment may be readily interpreted by a conditioning analysis of tolerance.     

Helping Police Officers to Cope with Stress: A Cognitive—Behavioral Approach

Police Academy trainees participated in a stress management program which focused on developing skills for coping with anxiety and anger. Stress management training took place in six 2-hour sessions and included instruction and practice in the self-monitoring of reactions to stressful situations, muscular relaxation, and the development of adaptive self-statements. Self-report measures of anxiety and anger were obtained before and after the stress management program. In addition, self and observer ratings of trainees' performance in stressful simulated police activities were utilized as posttreatment dependent measures. In comparison to a control group of trainees, the performance of the treatment group was rated, by academy personnel, as superior in several of the simulated police activities. The results of the present study suggest that stress management with law enforcement officers may be most effective when the program focuses on the specific situations which are likely to be encountered by trainees. Limitations of the present program are examined and suggestions for future efforts with law enforcement personnel are discussed.     

Voluntary Stigmatization and Social Comparison: Single Mothers View Their Lot1

This research examined the impact of voluntary Stigmatization, depression, and self-esteem on downward social comparisons. The stigmatized group was 51 mothers who chose to become parents as single women; 51 demographically similar married mothers were the nonstigmatized group. The women described their stressors and rated these stressors relative to other mothers of the same marital status and relative to mothers who differed in marital status. Consistent with downward comparison theory, Stigmatization increased the likelihood of making downward comparisons. Contrary to the theory, high self-esteem and low levels of depression resulted in self-enhancing comparisons, but only when individuals compared themselves to others who differed in Stigmatization status. The combination of these individual difference variables and Stigmatization increased the tendency to make downward comparisons.