The contribution of the inferior parietal cortex to spoken language production

This functional MRI study investigated the involvement of the left inferior parietal cortex (IPC) in spoken language production (Speech). Its role has been apparent in some studies but not others, and is not convincingly supported by clinical studies as they rarely include cases with lesions confined to the parietal lobe. We compared Speech with non-communicative repetitive tongue movements (Tongue). The data were analyzed with both univariate contrasts between conditions and probabilistic independent component analysis (ICA). The former indicated decreased activity of left IPC during Speech relative to Tongue. However, the ICA revealed a Speech component in which there was correlated activity between left IPC, frontal and temporal cortices known to be involved in language. Therefore, although net synaptic activity throughout the left IPC may not increase above baseline conditions during Speech, one or more local systems within this region are involved, evidenced by the correlated activity with other language regions.     

Kant's Modalities of Judgment

Abstract: This paper proposes a way to understand Kant's modalities of judgment—problematic, assertoric, and apodeictic—in terms of the location of a judgment in an inference. Other interpretations have tended to understand these modalities of judgment in terms of one or other conventional notion of modality. For example, Mattey (1986) argues that we should take them to be connected to notions of epistemic or doxastic modality. I shall argue that this is wrong, and that these kinds of interpretation of the modality of judgments cannot be reconciled with a key claim made by Kant, namely, that the modality of a judgment does not contribute to its content, and has nothing to do with the matter that is judged. I offer an alternative interpretation based upon Kant's explicating these modalities in terms of the location of a judgment in an inference, whereby the modality of a judgment is determined by the role a judgment plays in a given course of reasoning. If I am right, then Kant in fact presents an intriguing thesis pertaining to the inferential status and potential of all our judgments.     

Intracerebral scopolamine administration attenuates Pavlovian heart rate conditioning in the rabbit

Scopolamine hydrobromide was injected into the a) septum, b) dorsal hippocampus, or c) lateral ventricles of conscious rabbits via bilateral chronic indwelling cannulas. The cardiac orienting reflex (OR) and heart rate (HR) classical conditioning were assessed. A fourth group of animals received injections of the vehicle solution into these same brain areas and were otherwise similarly trained. Scopolamine had no effect on the cardiac OR produced by unreinforced tone stimuli. The OR consisted of pronounced bradycardia that habituated over successive trials in all groups. The HR change during classical conditioning also consisted of bradycardia. However, these conditional HR changes were attenuated by scopolamine injected into the septum and lateral ventricles, but were not affected by injections into the dorsal hippocampus. These results suggest that centrally applied scopolamine may affect a central nervous system associative process, and not a mechanism directly involved in primary bradycardia.     

Dimensions of distress tolerance and the moderating effects on mindfulness-based stress reduction

Background and Objectives: This study examined the relationship between distress tolerance and psychosocial changes among individuals participating in Mindfulness-Based Stress Reduction (MBSR). The objective of the analysis was to discern whether individuals with lower distress tolerance measured before MBSR showed larger reductions in perceived stress following MBSR. Design and Methods: Data were collected from a sample of convenience (n?=?372) using a quasi-experimental design. Participants completed self-report measures immediately prior to course enrollment and following course completion. Results: Perceived stress, distress tolerance, and mood states showed favorable changes from pre- to post-MBSR in the current study. Baseline distress tolerance significantly moderated reductions on perceived stress, supporting the primary hypothesis that individuals with lower baseline distress tolerance evidenced a greater decline in perceived stress following MBSR. For a one-unit increase on the self-reported baseline Distress Tolerance Scale, reported perceived stress scores decreased by 2.5 units (p?Conclusions: The finding that individuals with lower baseline distress tolerance evidenced a greater decline in perceived stress may offer hints about who is most likely to benefit from MBSR and other mindfulness-based treatments. Identifying moderators of treatment outcomes may yield important benefits in matching individuals to treatments that are most likely to work for them.     

Distributed processing and cortical specialization for speech and environmental sounds in human temporal cortex

Using functional MRI, we investigated whether auditory processing of both speech and meaningful non-linguistic environmental sounds in superior and middle temporal cortex relies on a complex and spatially distributed neural system. We found that evidence for spatially distributed processing of speech and environmental sounds in a substantial extent of temporal cortices. Most importantly, regions previously reported as selective for speech over environmental sounds also contained distributed information. The results indicate that temporal cortices supporting complex auditory processing, including regions previously described as speech-selective, are in fact highly heterogeneous.     

The influence of sex-role orientation on ratings of perceived exertion

Previous research has shown that feminine-typed women have an aversion to strenuous physical activity and when engaging in cross-sex behavior may experience psychological distress. Given the growing interest in aerobic exercise, the present study was designed to test whether sex-role orientation mediated the report of physical exertion. Subjects were 33 college-aged women selected from three categories: masculine, feminine, and androgynous. Procedures required that each subject complete two one-hour testing sessions. The first session was employed to collect anthropometric data and to evaluate maximum aerobic capacity, while the second session consisted of subjects completing a preperformance affect scale and subsequently running for 30 minutes at a preestablished work intensity. Results revealed that those who were feminine-typed gave significantly higher exertional ratings than either the masculine or androgynous women. The fact that the feminine group was less positive about the task suggests that the observed perceptual differences may have been due to affective schemata which have been hypothesized to mediate the perception of pain.This article is based on a master's thesis by the first author, but the second author assumed primary responsibility for the preparation of the present article.