Is lesion of Exner's area linked to progressive agraphia in amyotrophic lateral sclerosis with dementia? An autopsy case report

Agraphia, as a neuropsychological symptom of ALS, especially ALS with dementia (ALS-D), has recently attracted more attention. However, the brain lesion responsible has not been identified. Here we present an autopsy case of ALS-D of a patient with obvious agraphia, without aphasia, that also presented cerebrospinal degeneration with TDP-43-pathology compatible with ALS-D. Of the pre-motor frontal lobe cortices, degeneration and immuno-histochemical pathology were most obvious in the caudal area of the left middle frontal gyrus, or Exner's area. Assuring this area plays a pivotal role in the kanji and kana formation used in writing the Japanese language, this case of ALS-D showed both agraphia and Exner's area stressed pathological lesions. It may thus be the first case to indicate an intimate relationship between the neuropsychological symptoms and an associated lesion for ALS-D.     

Facial perception of conspecifics: chimpanzees (Pan troglodytes) preferentially attend to proper orientation and open eyes

This paper reports on the use of an eye-tracking technique to examine how chimpanzees look at facial photographs of conspecifics. Six chimpanzees viewed a sequence of pictures presented on a monitor while their eye movements were measured by an eye tracker. The pictures presented conspecific faces with open or closed eyes in an upright or inverted orientation in a frame. The results demonstrated that chimpanzees looked at the eyes, nose, and mouth more frequently than would be expected on the basis of random scanning of faces. More specifically, they looked at the eyes longer than they looked at the nose and mouth when photographs of upright faces with open eyes were presented, suggesting that particular attention to the eyes represents a spontaneous face-scanning strategy shared among monkeys, apes, and humans. In contrast to the results obtained for upright faces with open eyes, the viewing times for the eyes, nose, and mouth of inverted faces with open eyes did not differ from one another. The viewing times for the eyes, nose, and mouth of faces with closed eyes did not differ when faces with closed eyes were presented in either an upright or inverted orientation. These results suggest the possibility that open eyes play an important role in the configural processing of faces and that chimpanzees perceive and process open and closed eyes differently.     

Are spatial responses to visuospatial stimuli and spoken responses to auditory letters ideomotor-compatible tasks? Examination of set-size effects on dual-task interference

Previous studies have paired a visual-manual Task 1 with an auditory-vocal Task 2 to evaluate whether the psychological refractory period (PRP) effect is eliminated with two ideomotor-compatible tasks (for which stimuli resemble the response feedback). The present study varied the number of stimulus-response alternatives for Task 1 in three experiments to determine whether set-size and PRP effects were absent, as would be expected if the tasks bypass limited-capacity response-selection processes. In Experiments 1 and 2, the visual-manual task was used as Task 1, with lever-movement and keypress responses, respectively. In Experiment 3, the auditory-vocal task was used as Task 1 and the visual-manual task as Task 2. A significant lengthening of reaction time for 4 vs. 2 alternatives was found for the visual-manual Task 1 and the Task 2 PRP effect in Experiments 1 and 2, suggesting that the visual-manual task is not ideomotor compatible. Neither effect of set size was significant for the auditory-vocal Task 1 in Experiment 3, but there was still a Task 2 PRP effect. Our results imply that neither version of the visual-manual task is ideomotor compatible; other considerations suggest that the auditory-vocal task may also still require response selection.     

Is the psychological refractory period effect for ideomotor compatible tasks eliminated by speed-stress instructions?

It has been argued that the psychological refractory period (PRP) effect is eliminated with two ideomotor compatible tasks when instructions stress fast and simultaneous responding. Three experiments were conducted to test this hypothesis. In all experiments, Task 1 required spatially compatible manual responses (left or right) to the direction of an arrow, and Task 2 required saying the name of the auditory letter A or B. In Experiments 1 and 3, the manual responses were keypresses made with the left and right hands, whereas in Experiment 2 they were left-right toggle-switch movements made with the dominant hand. Instructions that stressed response speed reduced reaction time and increased error rate compared to standard instructions to respond fast and accurately, but did not eliminate the PRP effect on Task 2 reaction time. These results imply that, even when response speed is emphasized, ideomotor compatible tasks do not bypass response selection.     

The adaptive nature of children's overestimation in a strategic memory task

Kindergarten, first-, and third-grade children were given a multitrial sort-recall task with different items on each trial. Children were asked to predict how many items they would recall prior to each trial. We classified children into high- and low-overestimation groups based on their prediction accuracy on the first two trials and assessed changes in recall and strategy use over trials (trials 4/5 minus trials 1/2). Following predictions, at all grades, children in the high-overestimation group showed greater gains (or fewer losses) in recall than children in the low-overestimation group. Differences in strategy use over trials were generally nonsignificant. The results were interpreted as reflecting the adaptive nature of children's overestimation of their cognitive abilities.     

Changes in brain activation induced by the training of hypothesis generation skills: an fMRI study

The aim of the present study is to investigate the learning-related changes in brain activation induced by the training of hypothesis generation skills regarding biological phenomena. Eighteen undergraduate participants were scanned twice with functional magnetic resonance imaging (fMRI) before and after training over a period of 2 months. The experimental group underwent eight biological hypothesis generation training programs, but the control group was not given any during the 2-month period. The results showed that the left frontal gyri, the cingulate gyrus, and the cuneus were activated during hypothesis generation. In addition, the brain activation of the trained group increased in the left inferior and the superior frontal gyri, which are related to working memory load and higher-order inferential processes. However, the activation after training decreased in the occipito-parietal route, which is associated with the perception and the analysis processes of visual information. Furthermore, the results have suggested that the dorsolateral prefrontal cortex (DLPFC) region is the critical area in the training of hypothesis generation skills.     

Kant's Syntheticity Revisited by Peirce

This paper reconstructs the Peircean interpretation of Kant's doctrine on the syntheticity of mathematics. Peirce correctly locates Kant's distinction in two different sources: Kant's lack of access to polyadic logic and, more interestingly, Kant's insight into the role of ingenious experiments required in theorem-proving. In this second respect, Kant's analytic/synthetic distinction is identical with the distinction Peirce discovered among types of mathematical reasoning. I contrast this Peircean theory with two other prominent views on Kant's syntheticity, i.e. the Russellian and the Beckian views, and show how Peirce's interpretation of Kant solves the dilemma that each of these two views faces. I also show that Hintikka's criterion for Kant's synthetic judgments, i.e. a new individual introduced by the -instantiation rule, does not capture the most important characteristic of Peirce's theorematic reasoning, i.e. the process of choosing a correct individual.     

Verbal and visual recall span curves between 1 ms and 1 min

Summary The recall spans for verbal and visual information were represented, respectively, in terms of the number of digits and the number of dots in a 5×5 matrix. They were measured independently by the method of limits as functions of presentation times which ranged from 1 ms to 64 s. The curves were very similar: each had two plateaus, one at 10 to 100 ms and one at 2 to 8 s presentation levels. These plateaus suggest two kinds of capacity limitation on information processing. The first limitation is concerned with the transfer of information from iconic memory to short-term memory (STM); the second indicates the saturation of the limited capacity short-term store. Short-term and long-term mechanisms are involved not only in verbal memory but also in visual memory, since the second plateau followed by an increasing portion appears in the visual span curve as well as in the verbal one. Finally, the distinction between verbal and visual STM is discussed, based on a) the selective interference effects of distracting tasks upon the retention of verbal and visual materials, and b) the weak correlation between verbal and visual spans.     

A performance comparison between the two language versions of the Affective Go/No‐Go test: A randomised crossover study

The purpose of this randomised crossover study is to validate the Korean version of the Affective Go/No‐go (AGN) test. The Korean words for the AGN test were selected after careful evaluation of emotional valences, word length and frequency. Fifteen Korean advanced learners of English were administered both Korean and English versions, yielding 30 data points. The performance of both language versions was compared for each of the AGN test parameters (response latency, commission error and omission error) using two‐way analysis of variance (ANOVA). Intraclass correlation coefficients (ICCs) were estimated to evaluate associations between the two versions. The ICCs were high for response latencies of all valences and commission errors of positive and neutral words, but not for that of negative words and omission errors of all valences. A similar pattern of test results, as revealed by the high ICCs and non‐significant interaction effects between language and word valence, suggests that the psychometric properties of the AGN test may be comparable over different language versions.     

The Effects of Sociocultural Pressures and Exercise Frequency on the Body Esteem of Adolescent Girls in Korea

Sociocultural pressures to be thin and exercise frequency have been reportedly related to female adolescents’ body esteem in previous research. Using 490 female middle school students in Korea, this study examined the mediating role of thin-ideal internalization on the relationships of sociocultural pressure (i.e., parental, peer, and media) and exercise frequency to body esteem. The results indicated that parental pressure only had a direct relationship with body esteem, but no indirect relationship. Media pressure, peer pressure, and exercise frequency were indirectly, but not directly, related to body esteem through thin-ideal internalization. The implications and future directions of research are discussed.