Glutamatergic activation of anterior cingulate cortex mediates the affective component of visceral pain memory in rats

Studies of both humans and animals suggest that anterior cingulate cortex (ACC) is important for processing pain perception. We identified that perigenul ACC (pACC) sensitization and enhanced visceral pain in a visceral hypersensitive rat in previous studies. Pain contains both sensory and affective dimensions. Teasing apart the mechanisms that control the neural pathways mediating pain affect and sensation in nociceptive behavioral response is a challenge. In this study, using a rodent visceral pain assay that combines the colorectal distension (CRD)-induced visceromotor response (VMR) with the conditioning place avoidance (CPA), we measured a learned behavior that directly reflects the affective component of visceral pain. When CRD was paired with a distinct environment context, the rats spent significantly less time in this compartment on the post-conditioning test days as compared with the pre-conditioning day. Effects were lasted for 14 days. Bilateral pACC lesion significantly reduced CPA scores without reducing acute visceral pain behaviors (CRD-induced VMR). Bilateral administration of non-NMDA receptor antagonist CNQX or NMDA receptor antagonist AP5 into the pACC decreased the CPA scores. AP5 or CNQX at dose of 400 mM produced about 70% inhibition of CRD-CPA in the day 1, 4 and 7, and completely abolished the CPA in the day 14 after conditioning. We concluded that neurons in the pACC are necessary for the "aversiveness" of visceral nociceptor stimulation. pACC activation is critical for the memory processing involved in long-term negative affective state and prediction of aversive stimuli by contextual cue.     

二阶扩展逻辑的复杂性与表达能力

本文研究了在所有有穷结构上SO．HORN＊,SO—HORNτ和SO-HORNτ的表达能力。我们证明了SO-HORNτ,SO—HORN＊τ和FO（LFP）的表达能力是一致的,SO—HORN＊是SO-HORNτ的一个严格子逻辑。为了证明这一结果,我们提出了DATALOG＊程序,DATALOGτ程序以及它们的分层版本S-DATALOG＊程序利S-DATALOGτ程序。我们证明了在所有有穷结构上DATALOGτ和S-DATALOGτ是等价的,并且DATALOG。足DATALOGτ的一个严格子逻辑。最后我们还用两种方法证明了SO-HORN的一个扩展版本SO—EHORNτ逻辑可以在所有有穷结构有有结构上刻画co—NP。     

直觉和分析在不同任务条件下的逃生决策效果

目的：探讨针对简单和复杂逃生任务时, 直觉和分析在不同判断依据条件下的逃生决策效果。方法：采用两个主实验和两个预备实验。实验一和实验二的被试人数分别为：85人和87人。两个主实验均采取2 (思维方式：直觉和分析) × 2 (判断依据：简单和复杂)组间实验设计。主要结果：(1)针对简单逃生任务, 直觉组和分析组在不同判断依据条件下的逃生决策效果差异不明显; (2)针对复杂逃生任务, 在简单判断依据条件下分析决策优于直觉决策; 在复杂判断依据条件下直觉决策优于分析决策。主要结论：直觉性和分析性逃生决策的效果主要与决策任务的复杂程度有关, 而与判断依据的复杂程度关系不大。     

Quantitative defect evolution of nanocrystalline nickel during cold rolling

The defect evolution of cold-rolled nanocrystalline nickel is quantitatively investigated. We report that the density of dislocations (or stacking faults) first increases and then decreases after an equivalent strain of ～0.30. The density of stacking faults decreases more significantly than that of dislocations when the grain size increases above 35?nm. This is attributed to the grain size dependence of dislocation activity. The roles of texture and deformation twins are also considered to help understanding of the decreasing density of dislocations (or stacking faults).     

Effort and negative affect interact to predict cardiovascular responses to stress

Objective: Although traditional models posit that negative emotional responses to stress increase cardiovascular reactivity (CVR), laboratory studies have generally not found a strong emotion–CVR association. In this paper, we took a multidimensional approach to examining psychological reactions to stress in three studies.

Methods: In each study we assessed the amount of effort exerted by a participant and the negative affect (NA) felt by the participant with different self-reported measures and an effort behavioural measure.

Results: Our findings consistently demonstrated that NA was associated with CVR when effort was relatively high, but not when effort was relatively low.

Conclusion: This suggests that the weak NA–CVR correlations reported in past research may have been confounded by a third effort-related variable and that CVR is significantly associated with NA under certain circumstances. Furthermore, our findings suggest that by considering the multidimensional nature of psychological responses to stress, we may come to better understand the links between stress-related emotion and physiology.     

Effects of Image Preprocessing on Face Matching and Recognition in Human Observers

In person identification, recognition failure due to variations of illumination is common. In this study, we employed image‐processing techniques to tackle this problem. Participants performed recognition and matching tasks where the face stimuli were either original images or computer‐processed images in which shading was weakened via a number of image‐processing techniques. The results show that whereas recognition accuracy in a memory task was unaffected, some of the techniques significantly improved the identification performance in a face‐matching task. We conclude that relative to long‐term face memory, face matching is more susceptible to discrepancy of shading in different images of a face. Reducing the discrepancy by certain preprocessing techniques can facilitate person identification when original face images contain large illumination differences. Copyright © 2013 John Wiley & Sons, Ltd.     

Microstructure evolution and hardness variation of pack-rolled nanocrystalline nickel

The microstructure evolution and hardness of nanocrystalline nickel during pack rolling at room temperature have been investigated. It was found that the roll-bonding side (R) and non-roll-bonding side (NR) behaved quite differently. The hardness of side R is higher than that of side NR. No obvious work softening was observed in either side R or side NR until the strain reached ~ 0.611. Quantitative X-ray diffraction analysis indicated that the grain size in side NR increases faster than that in side R, a result confirmed by transmission electron microscopy. Texture analysis showed that (2 0 0) preferred orientation first strengthens but then weakens in both sides NR and R, while a strong (2 2 0) preferred orientation emerges, particularly in side R. Further texture analysis suggests that dislocation slip is responsible for the texture discrepancy between side NR and side R. The dislocation activity, grain rotation and grain growth are discussed based on the experimental results.     

东正教文化影响下巴金作品中的女性崇拜意识

中国现代著名作家巴金先生深受俄罗斯文学与文化的影响.而对巴金的小说创作影响最大的,则是极富俄罗斯特色的东正教文化中独有的女性崇拜的文化传统.巴金在其作品中塑造了一个个近乎完美的女性人物形象系列,其中所彰显出来的女性崇拜意识与他所受俄罗斯东正教文化的影响密不可分.     

Exploring Counselor-Client Agreement on Clients’ Work Capacity in Established and Consultative Dyads

Counselor-client agreement on the work capacity of clients living with serious mental illnesses informs the counseling relationship and facilitates accurate assessments of client eligibility for public programs. In this exploratory mixed-methods study, we assessed counselor-client agreement on clients’ work capacity in 61 established therapeutic dyads and compared it with 30 dyads involved in an initial assessment session. Intraclass correlation coefficients and mountain plots were used to examine counselor-client agreement. Results revealed moderate counselor-client agreement of work capacity for both dyads. Counselor interviews illuminated sources of discordance. These results have practical implications for assessing the work capacity of clients.