Characteristics and reversibility of dementia in Normal Pressure Hydrocephalus

Studies of the cognitive outcome after shunt insertion for treatment of Normal Pressure Hydrocephalus have reported widely mixed results. We prospectively studied performance of 60 patients with Normal Pressure Hydrocephalus on a comprehensive battery of neuropsychological tests before and after shunt surgery to determine which cognitive functions improve with shunt insertion. We also administered a subset of cognitive tests before and after temporary controlled drainage of cerebrospinal fluid to determine if change on this brief subset of tests after drainage could predict which patients would show cognitive improvement three to six months after shunt insertion. There was a significant improvement in learning, retention, and delayed recall of verbal memory three to six months after surgery (using paired t-tests). The majority (74%) of patients showed significant improvement (by at least one standard deviation) on at least one of the memory tests. Absence of improvement on verbal memory after temporary drainage of cerebrospinal fluid had a high negative predictive value for improvement on memory tests at 3-6 months after surgery (96%; p=0.0005). Also, the magnitude of improvement from Baseline to Post-Drainage on few specific tests of learning and recall significantly predicted the magnitude of improvement after shunt surgery on the same tests (r2=0.32-0.58; p=0.04-0.001). Results indicate that testing before and after temporary drainage may be useful in predicting which patients are less likely to improve in memory with shunting.     

Avoiding The Unavoidable? Judith Shklar’s Unwilling Search For An Overlapping Consensus

No less an authority than John Rawls identified Judith Shklar as a ‘political’ liberal. However, though their respective conceptions of political liberalism are similar in a number of important respects, Shklar emphasizes that her vision differs notably from that of Rawls. In particular, she explicitly eschews Rawls’s focus on establishing and sustaining an overlapping consensus, arguing that his belief in the possibility of securing such a consensus is naïve and, indeed, dangerous insofar as it embodies an obvious disregard for the painful lessons of history and thereby not only allows but invites the occurrence of new cruelties and horrors. Obviously, such an approach would seem to diverge dramatically from that promoted by Rawls and many other political liberals. The purpose of this essay is to analyze Shklar’s arguments and determine the validity of her claims regarding the differences between her conception and that of Rawls and, in so doing, assess the extent to which Shklar’s ‘liberalism of fear’ can be said to represent a meaningfully distinctive model of political liberalism.     

Associative and repetition priming with the repeated masked prime technique: No priming found

Wentura and Frings (2005) reported evidence of subliminal categorical priming on a lexical decision task, using a new method of visual masking in which the prime string consisted of the prime word flanked by random consonants and random letter masks alternated with the prime string on successive refresh cycles. We investigated associative and repetition priming on lexical decision, using the same method of visual masking. Three experiments failed to show any evidence of associative priming, (1) when the prime string was fixed at 10 characters (three to six flanking letters) and (2) when the number of flanking letters were reduced or absent. In all cases, prime detection was at chance level. Strong associative priming was observed with visible unmasked primes, but the addition of flanking letters restricted priming even though prime detection was still high. With repetition priming, no priming effects were found with the repeated masked technique, and prime detection was poor but just above chance levels. We conclude that with repeated masked primes, there is effective visual masking but that associative priming and repetition priming do not occur with experiment-unique prime-target pairs. Explanations for this apparent discrepancy across priming paradigms are discussed. The priming stimuli and prime-target pairs used in this study may be downloaded as supplemental materials from mc.psychonomicjournals. org/content/supplemental.     

When self-disclosure goes awry: Negative consequences of revealing personal failures for lower self-esteem individuals

Despite the potential benefits of self-disclosure, individuals with lower self-esteem (LSEs) tend to avoid self-revelations. The present study investigated the role of self-esteem in predicting detrimental responses to the disclosure of a personal failure. We employed a novel experimental design where all participants experienced a lab-induced stressor (failure feedback on a competence test) and half were randomly assigned to disclose this information to their dating partner. In contrast to LSEs who concealed the personal failure, LSEs who disclosed the failure reported several negative consequences that may further contribute to relationship-based distress. However, individuals higher in self-esteem (HSEs) benefitted from disclosing the personal failure in comparison to LSEs who disclosed and HSEs who concealed the failure. We discuss the consequences of disclosing personal failures to partners for HSEs and LSEs.     

Development of the positive–negative asymmetry effect: in‐group exclusion norm as a mediator of children's evaluations on negative attributes

Two studies were conducted that go beyond previous research by examining when and why children might show intergroup bias in the attribution of positive, but not negative traits (PNAE: the positive–negative asymmetry effect, Mummendey & Otten, 1998, European review of social psychology, Vol. 9). In Study 1 (n = 107) children completed a ‘mixed’ trait attribution task in a dichotomous group context. As predicted there was a developmental trend between 7 and 12 years of age in the PNAE. The 7‐year olds were the only age group not to show the effect. Study 1 also found a quadratic developmental trend in children's national intergroup bias. Study 2 (n = 62) replicated the developmental path of the PNAE found in Study 1 using a wider age range of 6–16 years. This study used a ‘mixed’ list of traits which were not only antonyms and a procedure that made the positive and negative trait dimensions explicitly independent. Significantly, Study 2 found in‐group exclusion norm partially mediated the development of the PNAE. These findings support an account of the positive–negative asymmetry effect based upon normative processes. Copyright © 2006 John Wiley & Sons, Ltd.     

Persistent symptoms among survivors of Hodgkin's disease: an explanatory model based on classical conditioning.

Persistent symptoms of nausea, distress, and vomiting triggered by reminders of cancer treatment were examined among 273 Hodgkin's disease survivors, 1 to 20 years posttreatment. Prevalence rates were high for distress and nausea but low for vomiting. Retrospective report of anticipatory symptoms during treatment was the strongest predictor of persistent symptoms, suggesting that treatment-induced symptoms are less likely to persist if conditioning does not occur initially. Time since treatment was also a significant predictor, with patients more recently treated more likely to experience persistent symptoms. Thus, an explanatory model based on classical conditioning theory successfully predicted presence of persistent symptoms. Symptoms also were associated with ongoing psychological distress, suggesting that quality of life is diminished among survivors with persistent symptoms. Recommendations for prevention and treatment of symptoms are discussed.     

Sentences for use in memory research

To investigate the effects of effort toward comprehension on subsequent recall, Auble, Franks, and Soraci (1979) generated a series of 40 sentences which varied in comprehensibility. We presented these sentences along with 60 new sentences to 122 undergraduates at the University of New Orleans. Sentences were rated for comprehensibility both before and after cue presentation. Sentences which appear most useful for research are discussed.