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951.
Ash S McMillan C Gross RG Cook P Gunawardena D Morgan B Boller A Siderowf A Grossman M 《Brain and language》2012,120(3):290-302
Few studies have examined connected speech in demented and non-demented patients with Parkinson’s disease (PD). We assessed the speech production of 35 patients with Lewy body spectrum disorder (LBSD), including non-demented PD patients, patients with PD dementia (PDD), and patients with dementia with Lewy bodies (DLB), in a semi-structured narrative speech sample in order to characterize impairments of speech fluency and to determine the factors contributing to reduced speech fluency in these patients. Both demented and non-demented PD patients exhibited reduced speech fluency, characterized by reduced overall speech rate and long pauses between sentences. Reduced speech rate in LBSD correlated with measures of between-utterance pauses, executive functioning, and grammatical comprehension. Regression analyses related non-fluent speech, grammatical difficulty, and executive difficulty to atrophy in frontal brain regions. These findings indicate that multiple factors contribute to slowed speech in LBSD, and this is mediated in part by disease in frontal brain regions. 相似文献
952.
Mastery motivation is a psychological force that stimulates an individual to attempt to master a task that is challenging to him or her. This prospective longitudinal study examined the relationship between maternal stress, using the Parenting Stress Index-Short Form, and infant mastery motivation, using the Dimensions of Mastery Questionnaire, for 150 mother-infant pairs assessed at both 6- and 18-months of age. Infants of mothers with elevated stress levels at 6 months tended to show lower mastery motivation at 18 months (standardized beta=-.46, p=.001). Conversely, infants with lower general competence (standardized beta=-.24, p=.021) and lower persistence during social interactions with other children (standardized beta=-.18, p=.037) at 6 months of age had mothers with elevated total stress at 18 months of age. Implications for programs which simultaneously intervene with child and mother are discussed. 相似文献
953.
This article explores the impact of consumers' regulatory goals on their relative focus on hedonic (versus utilitarian) benefits of products. Drawing from extant literature, we argue that promotion‐focused consumers will exhibit more favorable attitude towards a product when its hedonic benefits are highlighted in comparison to its utilitarian benefits. Prevention‐focused consumers on the other hand will exhibit more favorable attitude towards a product when its utilitarian benefits are highlighted in comparison to its hedonic benefits. We further argue that this effect is moderated by contextual factors, such as evaluation mode. In addition, we argue that the posited difference only holds when the hedonic and utilitarian products are evaluated individually. When the two products are evaluated jointly, both promotion and prevention‐focused individuals will exhibit more favorable attitude towards the hedonic product. Two studies were conducted to test the hypotheses and findings supported our predictions. Copyright © 2011 John Wiley & Sons, Ltd. 相似文献
954.
Margaret Malone Sharon Alger-Mayer John M. Polimeni 《Applied research in quality of life》2012,7(2):155-161
The majority of studies which have evaluated health related quality of life are limited in the duration of follow up. The
objective of this study was to prospectively conduct an evaluation using a repeated cross sectional analysis of separate patient
cohorts who were up to four years after gastric bypass surgery. Adult Roux-en-Y gastric bypass patients were recruited to
the study. All patients were requested to complete a general health status questionnaire, the Short Form-36 (SF-36), before
surgery or at their post operative out patient follow up visits. Patient weight was documented at each follow up visit. A
cross sectional analysis was performed to evaluate SF-36 scores in each annual cohort. Data are reported as mean +/− S.D.
Three-hundred-eight patients completed at least one SF-36 assessment [Initial assessment at the time of surgery, time 1, n = 245, 1y n = 149, 2y n = 70, 3y n = 59, 4y n = 61]. The SF-36 scores were greater (p < 0.05) in each of the separate post surgery cohorts for physical functioning, role limitations due to physical health, social
functioning, pain, vitality, general health and the physical component summary (PCS) scores. While not comparing changes in
scores within individuals over time, these data suggest early improvement especially in the physical dimension of health related
quality of life. In this analysis, this finding was also observed in each of the separate cohorts up to 4 years after gastric
bypass surgery. 相似文献
955.
Moore PJ Gratzer W Lieber C Edelson V O'Leary J Terry SF 《Journal of genetic counseling》2012,21(1):127-135
The Community Centered Family Health History project was initiated to create accessible family health history tools produced
by and for the community. The project goal was to promote increased community engagement in health education by encouraging
conversations among family members that would translate knowledge of family health history into healthy lifestyle choices.
As one of seven community partners, Iona College participated in customizing and beta-testing the Does It Run in the Family? toolkit. Twenty-nine college students were engaged to recruit three relatives related by blood to provide feedback on the
utility of the toolkit. The toolkit consists of two booklets—“A Guide to Family Health History” and “A Guide to Understanding
Genetics and Health”—explaining the importance of knowing and talking about health within the family as well as basics about
how conditions are passed down through generations. Twenty-two of the twenty-nine students participated in focus groups to
discuss their reactions to participation in the project. Students in the focus group reported that the study participants—students
and their family members—found the toolkit to be user friendly and the experience a valuable one that prompted many to take
positive steps toward good health. 相似文献
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959.
Sharon Krishek 《The Journal of religious ethics》2008,36(4):595-617
The duty to love one's neighbor as oneself is at the core of Kierkegaard's Works of Love. In this book, Kierkegaard unfolds the meaning of neighborly love and claims that it is the only valid form of true love. He contrasts between neighborly love and preferential love (which includes romantic love and friendship) and criticizes the latter for being nothing but a form of selfishness. However, in some contexts, Kierkegaard seems to acknowledge the significance of preferential love relationships, and does not disallow them. Therefore, his understanding of preferential love appears to be confused and inconsistent. My essay discusses the tension in Kierkegaard's position regarding preferential love, and by presenting recent readings of Works of Love, it asks whether this tension is resolvable and offers a suggestion for a possible solution. 相似文献
960.
ABSTRACTAlthough a bilingual advantage has been reported for various measures of cognitive control, most previous studies have looked at a limited range of cognitive control measures. Furthermore, they typically leave unaddressed whether positive effects of bilingualism hold for all bilinguals or whether these are modulated by differences in bilingual language use and proficiency of children and their parents. This study reports on tasks of selective attention and inhibitory control from 24-month-old bilinguals (n = 37) and monolinguals (n = 58). Their parents completed a Dutch vocabulary checklist assessing receptive and productive vocabulary as well as questionnaires on children’s attentional focusing, attention shifting and inhibitory control, and language background. Linear mixed-effect regressions showed no differences on cognitive control between the monolinguals and bilingual groups. However, analyses taking into account differences in children’s bilingual language use and proficiency and of their parents revealed a more nuanced picture. Specifically, children’s degree of balanced language usage predicted parent-rated cognitive control. Furthermore, bilingual toddlers who had parents were low proficient in one of the home languages showed significantly better performance on a selective attention task than toddlers whose parents were both proficient in both home languages. These findings suggest that both children’s active usage of two languages and their experience with switching depending on their interlocutor are related to cognitive control performance in young bilingual children. As such, they add to a growing body of evidence that the bilingual advantage in cognitive control is tied to specific conditions of bilingualism, already at a young age. 相似文献