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941.
Although the neighborhood microsystem is recognized as an important domain for adolescent development, relative to the family and peer contexts, neighborhood factors have been understudied in relation to adolescent substance abuse. In addition, recent research suggests that risk factors for adolescent substance use may differ for African Americans when compared to Caucasian youth. This study investigated the association between perceived neighborhood disorganization and later substance use, as well as possible mediators of that association, among a community sample of urban African American adolescents. Perceptions of neighborhood disorganization (i.e., violence/safety and drug activity) in grade 7 were associated with increased tobacco, alcohol, and marijuana use in grade 9. For females, this association was mediated by attitudes about drug use and perceptions of drug harmfulness. Findings highlight the importance of neighborhood contextual variables for African American substance use. Implications and directions for future research are presented.  相似文献   
942.
943.
The lateral prefrontal cortex has been implicated in a wide variety of functions that guide our behavior, and one such candidate function is selection. Selection mechanisms have been described in several domains spanning different stages of processing, from visual attention to response execution. Here, we consider two such mechanisms: selecting relevant information from the perceptual world (e.g., visual selective attention) and selecting relevant information from conceptual representations (e.g., selecting a specific attribute about an object from long-term memory). Although the mechanisms involved in visual selective attention have been well characterized, much less is known about the latter case of selection. In this article, we review the relevant literature from the attention domain as a springboard to understanding the mechanisms involved in conceptual selection.  相似文献   
944.
Functional magnetic resonance imaging (fMRI) distinguished regions of neural activity associated with active maintenance of semantic and phonological information. Subjects saw a single word for 2 sec, and following a 10-sec delay, made a judgment about that word. In the semantic task, subjects focused on the meaning of the word and decided whether a second word was synonymous with it. In the phonological task, subjects repeated the word silently and decided whether it shared a vowel sound with a nonsense word. Analyses allowed for isolation of neural activity during the maintenance delay. Semantic maintenance elicited greater activity in bilateral inferior frontal gyrus and left middle temporal gyrus regions of interest (ROI). In contrast, there was greater activity for phonological maintenance in the left superior parietal ROI. These results show a frontal-temporal network involved in actively maintaining the meanings of words, and they indicate that semantic and phonological maintenance processes are dissociable within working memory.  相似文献   
945.
In a previous study (Dronkers, 1996), stroke patients identified as having apraxia of speech (AOS), an articulatory disorder, were found to have damage to the left superior precentral gyrus of the insula (SPGI). The present study sought (1) to characterize the performance of patients with AOS on a classic motor speech evaluation, and (2) to examine whether severity of AOS was influenced by the extent of the lesion. Videotaped speech evaluations of stroke patients with and without AOS were reviewed by two speech-language pathologists and independently scored. Results indicated that patients with AOS made the most errors on tasks requiring the coordination of complex, but not simple, articulatory movements. Patients scored lowest on the repetition of multisyllabic words and sentences that required immediate shifting between place and manner of articulation and rapid coordination of the lips, tongue, velum, and larynx. Last, all patients with AOS had lesions in the SPGI, whereas patients without apraxia of speech did not. Additional involvement of neighboring brain areas was associated with more severe forms of both AOS as well as language deficits, such as aphasia.  相似文献   
946.
The present study characterizes the neural correlates of noun and verb imageability and addresses the question of whether components of the neural network supporting word recognition can be separately modified by variations in grammatical class and imageability. We examined the effect of imageability on BOLD signal during single-word comprehension of nouns and verbs. Subjects made semantic similarity judgments while undergoing functional magnetic resonance imaging (fMRI). Nouns and verbs were matched on imageability, and imageability varied continuously within a grammatical category. We observed three anatomically separable effects: a main effect of grammatical class, a main effect of imageability, and an imageability by grammatical class cross-over interaction. The left superior parietal lobule and a region in the left fusiform responded similarly to increases in noun and verb imageability; the left superior temporal gyrus showed greater activity for verbs than nouns after imageability was matched across grammatical class; and, in both the left middle temporal gyrus and the left inferior frontal lobe, a decrease in noun but not verb imageability resulted in higher BOLD signal. The presence of reliable and anatomically separable main effects of both imageability and grammatical class renders unlikely the hypothesis that previously reported dissociations between nouns and verbs can be dismissed as imageability effects. However, some regions previously thought to respond to grammatical class or imageability instead respond to the interaction of these variables.  相似文献   
947.
The completion of partly occluded objects appears instantaneous and effortless, but empirically takes measurable time. The current study investigates how amount of occlusion affects the time course and mechanisms of visual completion. Experiment 1 used a primed-matching paradigm to determine completion times for objects occluded by various amounts. Experiments 2 and 3 used a dot-localization paradigm to probe completed contour representations for a qualitative shift above some spatial limit. The results demonstrate that time to completion rises with amount of occlusion. Nonetheless, the visual system can complete highly occluded objects, even when the occlusion renders visible contours nonrelatable. Furthermore, prolonged completion times for highly occluded objects do not result from a breakdown of low-level interpolation processes: The same contour completion mechanism operates on objects occluded by different spatial extents.  相似文献   
948.
D. Briihl and A. W. Inhoff (1995; see record 1995-20036-001) found that exterior letter pairs showed no privileged status in reading when letter pairs were presented as parafoveal primes. However, T. R. Jordan, S. M. Thomas, G. R. Patching, and K. C. Scott-Brown (2003; see record 2003-07955-013) used a paradigm that (a) allowed letter pairs to exert influence at any point in the reading process, (b) overcame problems with the stimulus manipulations used by Briihl and Inhoff (1995), and (c) revealed a privileged status for exterior letter pairs in reading. A. W. Inhoff, R. Radach, B. M. Eiter, and M. Skelly (2003; see record 2003-07955-014) made a number of claims about the Jordan, Thomas, et al. study, most of which focus on parafoveal processing. This article addresses these claims and points out that although studies that use parafoveal previews provide an important contribution, other techniques and paradigms are required to reveal the full role of letter pairs in reading.  相似文献   
949.
Hebrew words are composed of two interwoven morphemes: a triconsonantal root and a word pattern. We examined the role of the root morpheme in word identification by assessing the benefit of presentation of a parafoveal preview word derived from the same root as a target word. Although the letter information of the preview was not consciously perceived, a preview of a word derived from the same root morpheme as the foveal target word facilitated eye-movement measures of first-pass reading (i.e.,first fixation and gaze duration). These results are the first to demonstrate early morphological effects in the context of sentence reading in which no external task is imposed on the reader, and converge with previous findings of morphemic priming in Hebrew using the masked priming paradigm, and morphemic parafoveal preview benefit effects in a single-word identification task.  相似文献   
950.
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