Chicks Injected with Antisera to either S-100α or S-100β Protein Develop Amnesia for a Passive Avoidance Task

The cellular expression of S-100β protein is upregulated in Alzheimer's disease and in Down's syndrome, and this protein has been implicated in memory-related processes in laboratory animals. However, the possibility that the α subunit of S-100 is also involved in memory has not yet been examined. In the present study, day-old black Australorp white Leghorn cockerel chicks (Gallus domesticus) received injections of monoclonal antisera to S-100α (1:50) or S-100β (1:500) into each hemisphere immediately after training on a one-trial passive avoidance task. The chicks displayed significantly lower retention levels than control birds that had been injected with antisera to carbonic anhydrase, or with saline (p< .01). S-100α antisera had an amnestic effect when injected between 0 and 20 min after training, with memory deficits occurring from 30 min postlearning, at the point of transition between the A and the B phases of the Gibbs-Ng intermediate memory stage. By contrast, the S-100β antisera needed to be injected either 5 min before or immediately after training and produced amnesia 10 min earlier, at the start of the A phase of the intermediate memory stage. We conclude that the two subunits of the S-100 protein are required at different points in the sequence of events leading to the consolidation of passive avoidance memory.     

3─6岁儿童传递性关系推理的研究

设计三种情境考察被试的推理情况,并试图揭示儿童是怎样进行传递性关系推理的。结果显示：（１）３—６岁儿童具有进行传递性关系推理能力;（２）造成我国３—６岁儿童作传递性关系推理失败的原因有二：一是错误理解比较句式,二是没有记住前提;（３）３—６岁儿童进行传递性关系推理的内部过程不同：小年龄段被试多采用“局部加工模式”,大龄段被试多采用“整体空间加工模式”。     

创业倾向影响因素研究

本文是有关个体创业倾向与其社会环境、个性特征以及其它相关因素的研究。目的是为了探讨个体的个性特征以及环境、背景等因素对其创业倾向的影响。研究以国际前沿的理论为基础，以建立个体创业倾向的影响因素模型为目标。来研究个体创业倾向与社会环境、个性特征等影响因素的关系。     

快速眼动相(REM)睡眠剥夺对大鼠记忆巩固的影响

本实验应用小站台水环境技术剥夺大鼠快速眼动相(REM)睡眠,比较了在学习后不同时间剥夺REM睡眠对记忆巩固的影响异同,结果证明:大鼠在学习后,立即剥夺REM睡眠24小时对记忆巩固明显不利;如在立即剥夺REM睡眠24小时后再让其恢复自由睡眠24小时,记忆成绩无明显改善;学习后允许自由睡眠24小时对记忆巩固明显有利;如在自由睡眠24小时后再行REM睡眠剥夺24小时,记忆成绩仍保持良好。说明学习后一段时间自由睡眠对于记忆的巩固是重要的,剥夺REM睡眠对于记忆的巩固明显不利。     

文昌鱼的光动反应

文昌鱼的中枢神经系统早在上个世纪就受到神经解剖学家们的注意。这是因为它代表着动物演化上的一个很典型的阶段。在这个阶段,动物身体的背侧开始有了神经管。这个神经管在外形上很象脊椎动物胚胎初期形成的神经管,其内部的神经组织也较简单。此外,正如神经管初成阶段的脊椎动物胚胎一样,文昌鱼还不具备发育的和特异     

皮质下电刺激的抑制作用

在猴和黑猩猩的大脑皮质上有某些区域,用电刺激时可以抑制运动和降低脑电图(EEG)的幅度。这些区域被称为抑制区。但是刺激这些区域所产生的抑制效果不是经常有的,在一定程度上取决于麻醉的深度。有时在刺激过后几分钟才出现。持续时间可长达30分钟。 本文报告的是在清醒的、自由活动着的动物中,通过埋植的电极,刺激脑的深部结构所观察到的抑制脑的自发电活动的现象。     

灵长动物初级抽象概括能力的比较实验研究(Ⅰ)金丝猴对实物、照片和画片的概括

本实验的目的是研究金丝猴对于从三维客体到其二维的照片及图片的概括能力。实验在三只未成年金丝猴身上进行。在基础训练中,训练动物辨别墨水瓶模型和小房子模型。然后用它们的照片和图画进行测验。实验表明三只金丝猴都不能把对客体的辨别迁移到照片和图画上去。     

庆祝宗教文化出版社、中国宗教杂志社成立十周年座谈会在京举行

7月29日,庆祝中国宗教杂志社、宗教文化出版社成立十周年座谈会在北京人民大会堂隆重举行。全国人大常委会副委员长、中国天主教爱国会主席、中国天主教主教团代主席傅铁山,国家宗教事务局局长叶小文,副局长王作安、齐晓飞、蒋坚永,中国佛教协会会长一诚、副会长圣辉、净慧、学     

Correlations between Dual-Pathway White Matter Alterations and Language Impairment in Patients with Aphasia: A Systematic Review and Meta-analysis

Neuropsychology Review - While converging evidence suggests linguistic roles of white matter tracts, detailed associations between white matter alterations of dual pathways and language abilities...     

High impulsivity,low self-control and problematic mobile phone use: The effect of poor sleep quality

Current Psychology - In order to ascertain the onset mechanism of problematic mobile phone use (PMPU), the current study tested the mechanism by which sleep quality is associated with PMPU though...