老年人声音诱发闪光错觉的大脑静息态低频振幅

声音诱发闪光错觉(sound-induced flash illusion, SiFI)是一种听觉占主导性的多感觉整合现象,即当视觉闪光伴随不相等数量的听觉声音在100 ms内相继或同时呈现时,个体会错觉性地知觉到视觉闪光的个数与听觉声音的数量相等。本研究分别将老年人群体和年轻人群体的声音诱发闪光错觉量(裂变错觉和融合错觉)与全脑的静息态低频振幅(amplitude of low-frequency fluctuation, ALFF)进行相关分析,考察老年人群体声音诱发闪光错觉效应与大脑静息状态自发活动区域的关系。结果发现,无论是裂变错觉还是融合错觉,老年人声音诱发闪光错觉均增大。对于裂变错觉,老年人的错觉量与内侧前额叶皮层的自发活动呈显著正相关;对于融合错觉,老年人的错觉量与额下回、额中回和颞下回的自发活动呈显著正相关,与枕上回和舌回的自发活动呈现显著的负相关。结果表明,老年人声音诱发闪光错觉量增大的原因与大脑中多个脑区的静息态自发活动存在关系。     

知情同意的风险决策能力评估探究

能力是知情同意的“守门人”概念,风险相关决策能力将患者的行为能力与具体决策风险结合起来,并充分考量其法律依据与医学特点。一般情况下,临床实践并不需要评估患者的决策能力。但是,当患者拒绝医生提出的最有利患者的建议,患者同意会伤害其本身利益的决策,以及患者前后决策相互矛盾且后期决策会伤害患者健康的情况下,需要评估。风险相关决策能力评估需要考察患者的沟通能力、信息理解能力、评估能力和道德推理能力。其道德合理性在于“行善”的价值辩护,在实践操作中需要借助个体的“实践智慧”。     

临床代理决策中的利益冲突及其消解

对于限制/无行为能力患者的医疗决策采取代理决策模式,该模式奠基于社会习俗与习惯法。通常情况下,亲属能够更加准确地评判患者的个人价值取向和医疗决定偏好。但是,基于利益判断的主观性,代理决策中的道德冲突难以避免,其合理性辩护基于代理身份的合法性、“善意”与“患者利益”的标签、制度缺失,对于其批评在于代理者德性基础上的一致性不足。按照解决问题的逻辑进程,规避代理决策中利益冲突的方式有寻求共识的可能、临床伦理咨询与司法介入,其中伦理咨询与司法介入需要依托国家制度设计。     

中小学教师的工作倦怠与其相关因素的关系研究

本研究旨在探讨中小学教师的工作倦怠与其职业压力应对策略、教学效能感和社会支持的关系。用教师工作倦怠问卷、职业压力应对策略调查表、教学效能感量表和社会支持评定量表对766名中小学教师进行了问卷调查。结果发现：（1）中小学教师的工作倦怠与其职业压力应对策略、教学效能感和社会支持之间存在显著的相关关系;（2）教师的主动应对、被动应对、教学效能感和社会支持分别对教师的整体工作倦怠感及其情绪衰竭、非人性化和低成就感等维度具有显著的预测作用。     

汉语句子可继续性对句子理解加工的即时影响

通过操纵动词与后接词的关系,来产生搭配异常并控制句子的可继续性,研究汉语词汇信息在句子加工中的即时作用。实验一利用跨通道技术,发现动一名词搭配异常对目标名词的加工有即时影响,形容词条件下可继续性对目标形容词的加工有即时影响;实验二采用眼动技术,发现名词条件和形容词条件下可继续性均有显著的即时影响。结果显示,语义等多种词汇信息被通达后立即共同参与了汉语句子加工。     

快速命名对汉语阅读的选择性预测作用

本研究采用分层回归的分析方法,考察了不同阅读能力组中快速命名(Rapid Automatized Naming,RAN)、汉字阅读和快速阅读之间的关系。为了控制IQ和年龄的作用,分层回归中IQ和年龄被放入回归方程的第一层。通过变换自变量进入方程的顺序,本研究分别考察了不同阅读水平组的RAN和汉字阅读对快速阅读的相对重要性。研究结果表明,RAN对阅读障碍组的汉字阅读的解释率更大,对于快速阅读的预测,结果表明RAN对不同阅读能力和不同的阅读过程具有选择性的预测作用。     

Temporal Coding in Pavlovian Conditioning: Hall-Pearce Negative Transfer

The Hall-Pearce (1979) negative transfer effect in rats was used to examine whether temporal relationships are coded as part of the informational content of associations that result from CS-US pairings. The transfer effect consists of adeficit in conditioned responding following CS-US pairings in Phase 2 that results from prior CS-US pairings in Phase 1. strong weak Using conditioned bar-press suppression, we found that gaps of different duration between CS termination and US onset in the two training phases resulted in less of a Hall-Pearce negative transfer effect than did an equivalent gap in the twotraining phases. The results are discussed with respect tothe temporal coding hypothesis (Matzel, Held, &Miller, 1988), the Pearce and Hall (1980) model, and Bouton's (1993) interference model.     

Vocabulary growth rate from preschool to school‐age years is reflected in the connectivity of the arcuate fasciculus in 14‐year‐old children

The acquisition of language involves the functional specialization of several cortical regions. Connectivity between these brain regions may also change with the development of language. Various studies have demonstrated that the arcuate fasciculus was essential for language function. Vocabulary learning is one of the most important skills in language acquisition. In the present longitudinal study, we explored the influence of vocabulary development on the anatomical properties of the arcuate fasciculus. Seventy‐nine Chinese children participated in this study. Between age 4 and age 10, they were administered the same vocabulary task repeatedly. Following a previous study, children's vocabulary developmental trajectories were clustered into three subgroups (consistently good, catch‐up, consistently poor). At age 14, diffusion tensor imaging data were collected. Using ROI‐based tractography, the anterior, posterior and direct segments of the bilateral arcuate fasciculus were delineated in each child's native space. Group comparisons showed a significantly reduced fractional anisotropy in the left arcuate fasciculus of children in the consistently poor group, in particular in the posterior and direct segments of the arcuate fasciculus. No group differences were observed in the right hemisphere, nor in the left anterior segment. Further regression analyses showed that the rate of vocabulary development, rather than the initial vocabulary size, was a specific predictor of the left arcuate fasciculus connectivity.     

儿童支气管异物32例误诊分析

支气管异物系儿科常见病,误诊原因很多,如病史陈述不详细、辅助检查的干扰等,更重要的一个原因就是异物的不典型位置。传统观念中,右下肺异物高发,实际上,受气流及异物体积的影响,轻而小的塑料可被回吸进入左上肺,而较大的异物受自身重力影响多进入右下肺。异物进入体内,引起的·临床表现多种多样,咳嗽、咯血、喘息甚至呼吸困难等,诸类症状在呼吸系统疾病中较为常见,因此这些症状的鉴别就显得尤为重要。在治疗方面,突破传统的支气管镜技术,提倡可以首先采取保守治疗,给予拍背、体位引流等手段,部分患儿可自行咳出异物,这样就避免了手术的风险,在保守治疗无效的情况下可转入外科通过纤维支气管镜取出。