学习困难儿童诊断量表常模制定

"学习困难检查表"在上海范围内向1067名被试施测后,本研究对所获数据进行了初步分析,得到(1)各变量原始数据的均数和标准差.(2)各变量原始数据有显著年龄差异和性别差异.(3)信效度检验结果基本符合心理测量学要求.(4)制定了上海地区常模.     

序列学习的ERP研究综述

对近些年国外序列学习的ERP研究进行了总结.序列学习研究选取的ERP成分主要包括N200、P300、CNV、LRP、ERN、MMN等;关注的问题主要集中在意识与序列学习的关系、序列学习的表征问题以及序列学习中一些相似ERP成分的差异等方面.     

Purple sweet potato color repairs d-galactose-induced spatial learning and memory impairment by regulating the expression of synaptic proteins

Purple sweet potato color (PSPC), a class of naturally occurring anthocyanins used to color food (E163), has been reported to possess a variety of biological activities, including anti-oxidant, anti-tumor, and anti-inflammatory. The effect of PSPC on the spatial learning and memory of mice treated with d-galactose (d-gal) was evaluated by the Morris water maze; d-gal-treated mice had decreased performance compared with mice in the vehicle and PSPC groups, while the PSPC + d-gal group showed significantly shortened escape latency to platform, increased swimming speed, more target quadrant search time and more platform crossings as compared with the d-gal group. Brain functions, such as memory formation and recovery of function after injury, depend on proper regulation of the expression levels of the pre- and post-synaptic proteins. We investigated the expression of four pre-synaptic proteins (growth-associated protein-43, synapsin-I, synaptophysin, and synaptotagmin) and two post-synaptic proteins (post-synaptic density protein-95 and Ca²⁺/calmodulin-dependent protein kinase II) in the hippocampus and cerebral cortex, respectively, in response to different treatments. Western blotting analysis showed that there were significant decreases in the expression of these representative synaptic proteins in the hippocampus and cerebral cortex of d-gal-treated mice. Interestingly, these decreased expression levels of synaptic proteins could be reversed by PSPC. The levels of expression of these representative synaptic proteins in mice treated with PSPC alone were not significantly different from those in untreated mice. The results of this study suggested that memory impairment and synaptic protein loss in d-gal-treated mice may be improved by treatment with PSPC.     

微生物与行为和精神疾病

病原微生物能够影响宿主的大脑和行为, 甚至诱发精神疾患。肠道细菌可影响小鼠的神经系统发育和行为模式的发展。慢性胃肠病、慢性疲劳综合征等生理疾病中的行为改变与微生物有关; 肝性脑病、多发性硬化等中枢神经系统生理疾病也可能由微生态改变引起; 抑郁症、孤独症等精神疾病与肠道细菌状态和比例有关; 卫生假说支持上述观点。建立良好的共生微生物平衡有利于人类身心健康。可以预期, 共生微生物与身心健康的关系将是今后心理学研究的关注热点。     

不同的拼音教学方式对幼儿拼音水平及汉语语音意识发展的影响

本研究用纵向实验的方法考察了分享阅读(故事教学)和传统教学(字母教学)两种拼音教学方式对幼儿园中班儿童的拼音水平和汉语语音意识发展的影响。研究结果表明:(1)相对于无拼音教学组,两种形式的拼音教学均可以显著提高幼儿的字母知识,但分享阅读拼音教学对幼儿字母知识的促进作用更大。(2)分享阅读的拼音教学可以显著提高幼儿的拼读能力,而传统教学对幼儿的拼读能力基本没有促进。(3)分享阅读的拼音教学对幼儿的首音、韵脚和声调意识的发展有显著的促进作用,对幼儿自然发展起来的音节意识的影响很小;传统教学对幼儿的语音意识基本没有促进。     

乙肝治疗路线图与核苷类药物的耐药管理

慢性乙肝治疗的路线图介绍了对核苷类似物耐药的监测时间和处理方法。本文首先介绍了耐药评价的时间点,大多可以采用治疗后12周和24周的评估。如果出现耐药,针对不同情况可以采用换用或者加用没有交叉耐药的不同核苷类似物处理。     

疾病的哲学思考——坦然和平静地对待疾病

面对人类无法改变与疾病共存的命运,本文从健康与疾病的关系、疾病的原因、疾病的话语、对待疾病的态度和利用疾病的契机五个方面来进行哲学追问和反思.以期使我们通过倾听身体的语言,来坦然、自然和平静地对待疾病;利用疾病的契机,获得身心的成长,使人类的生命在亘古的绵延中永远充盈着盎然的生机.     

核心价值体系与国家之前途和命运

核心价值体系是国家意识形态的核心内容.核心价值体系是国家经济社会发展、政治变革的价值动力;也是国家之间意识形态竞争的主要内容.核心价值体系决定着国家的前途和命运,建设与国家前途、世界命运相适应的核心价值体系意义重大.     

Contextual adjustments in cognitive control across tasks

Does encountering information-processing conflict recruit general mechanisms of cognitive control or change only the representations of specific cues and responses? In the present experiments, a flanker task elicited responses to symbolic information (arrow meaning), whereas Stroop-like tasks elicited responses to nonsymbolic information (color of a letter or location of a target box). Despite these differences, when participants performed the flanker and Stroop tasks intermittently in randomized orders, the extent of information-processing conflict encountered on a particular trial modulated performance on the following trial. On across-task trial pairs, increases in response time to incongruent relative to congruent stimulus arrays were smaller immediately following incongruent trials than immediately following congruent trials. The degree of cognitive control exerted on a particular task thus appears to reflect not only the quality, but also the quantity, of recent experiences of information-processing conflict.