The effect of prenatal hypoxia on brain development: short- and long-term consequences demonstrated in rodent models

Hypoxia (H) and hypoxia-ischemia (HI) are major causes of foetal brain damage with long-lasting behavioral implications. The effect of hypoxia has been widely studied in human and a variety of animal models. In the present review, we summarize the latest studies testing the behavioral outcomes following prenatal hypoxia/hypoxia-ischemia in rodent models. Delayed development of sensory and motor reflexes during the first postnatal month of rodent life was observed by various groups. Impairment of motor function, learning and memory was evident in the adult animals. Activation of the signaling leading to cell death was detected as early as three hours following H/HI. An increase in the counts of apoptotic cells appeared approximately three days after the insult and peaked about seven days later. Around 14-20 days following the H/HI, the amount of cell death observed in the tissue returned to its basal levels and cell loss was apparent in the brain tissue. The study of the molecular mechanism leading to brain damage in animal models following prenatal hypoxia adds valuable insight to our knowledge of the central events that account for the morphological and functional outcomes. This understanding provides the starting point for the development and improvement of efficient treatment and intervention strategies.     

Mothers' psychological adjustment following disaster affecting their children

The authors investigated the psychological adjustment of 37 British women whose adolescent children survived the cruise ship Jupiter's sinking in 1988, about 6 years previously. They compared these women with a group of widows (N = 18) and a group of women who had suffered no major negative life event (N= 15). Psychological adjustment of the 37 women was assessed with the Schedule for Affective Disorders and Schizophrenia Lifetime Version (SADS-L; R. L. Spitzer & J. Endicott, 1975) and various standard questionnaires. The women whose children had been involved in the disaster were found to have suffered a greater number of incidents of psychological distress in the period since the disaster than the women who had suffered no major negative life events but fewer incidents of psychological distress than the widows. The significance of these findings and clinical implications are discussed.     

A comparative analysis of perceptual and demographic predictors of sense of place dimensions in the State Mosques of Malaysia

The study in this article is part of a more in‐depth research investigating the architectural and physical design influences on sense of place dimensions in the context of contemporary mosques in Malaysia. The focus of this paper is human–place bonding in sacred and religious settings, based on a framework including aspects of sociality, physicality and spirituality, in addition to demographic variables such as ranges of length of experience with, and frequency of presence in, the environment of the studied mosques. The effects of the perceptions of architecture and physical design, social environment, and spiritual atmosphere on dimensions of sense of place were studied using a structural equation modelling analysis based on 302 questionnaires completed in seven state mosques across the Southeast Asian country of Malaysia. Meanwhile the socio‐demographic effects on sense of place dimensions were also tested based on several analyses of variances (ANOVA) in various demographic groups through sense of place dimensions. In doing so, we adopted the multi‐dimensional approach towards sense of place consisting of cognitive, affective, and behavioral dimensions. As major findings, this research provided empirical evidence for the existence of direct relationships between perceptions of the key environmental factors studied and the sense of place dimensions in contexts with extensive religious and sacred attributes; on the other hand, no interactive relationship was found between most of the socio‐demographic variables and those dimensions. This article discusses in detail each of those approved and rejected relationships.     

Correction to: Comparison Study of the Effects of Resistance and Endurance Exercise Interventions for the Treatment of Depression: A Meta-Analytical Review

Journal of Contemporary Psychotherapy -     

Mothers' Psychological Adjustment Following Disaster Affecting Their Children

The authors investigated the psychological adjustment of 37 British women whose adolescent children survived the cruise ship Jupiter's sinking in 1988, about 6 years previously. They compared these women with a group of widows (N = 18) and a group of women who had suffered no major negative life event (N = 15). Psychological adjustment of the 37 women was assessed with the Schedule for Affective Disorders and Schizophrenia Lifetime Version (SADS-L; R. L. Spitzer & J. Endicott, 1975) and various standard questionnaires. The women whose children had been involved in the disaster were found to have suffered a greater number of incidents of psychological distress in the period since the disaster than the women who had suffered no major negative life events but fewer incidents of psychological distress than the widows. The significance of these findings and clinical implications are discussed.     

RETRACTED ARTICLE: Considering the Relationship Between Language,Culture and Cognition to Scrutinize the Lexical Influences on Cognition

In this paper, we examine the interrelationships among language, culture, and cognition. The central notion that individuals with different linguistic and cultural backgrounds think differently is not far from our everyday experience. If you have had the opportunity to engage in a conversation with a person whose native language is not English, you may have found that communication breaks down at times and that some concepts are not easily translated into another language. Or if you happen to be a fluent bilingual or multilingual, you may agree with those bilinguals or multilinguals who mention that they think differently in each of their language. A number of intriguing questions arise here. Is there a particular style of thinking that is natural for speakers of each language? If so, is it possible for a person to think in a different way, one that is not natural for that individual? Is this style of thinking imparted by the language, the culture, or both? These and lots of other questions have engaged the attention of anthropologists, linguists and psychologists, but the point that we are going to explore is the lexical influences on cognition considering the relationship between language, culture and cognition.     

Effect of facial stimuli exposure time on evaluation of facial attractiveness

Facial attractiveness has advantages both socially and sexually, and the human brain has evolved to perceive specific facial characteristics as attractive. The current research examined the effect of facial stimuli exposure time on facial attractiveness evaluations. In Experiment 1, 86 students observed 44 facial stimuli in short and long amounts of time. To eliminate any influence of repeated stimuli on the second observations, Experiment 2 was performed on 84 participants who observed the facial stimuli in either short or long durations. Differences in both experiments were significant. These studies showed that exposure time has an influence on the evaluation of facial attractiveness. Participants who were exposed to facial stimuli for a short amount of time perceived greater facial attractiveness than when they were exposed for a longer time to the same stimuli. In other words, faces were more beautiful when they were observed in a short amount of time, and this effect occurred regardless of gender.     

The effect of acute stress exposure on ischemia and reperfusion injury in rat heart: role of oxytocin

Previous studies showed the protective effects of oxytocin (OT) on myocardial injury in ischemic and reperfused rat heart. Moreover, exposure to various stressors not only evokes sudden cardiovascular effects but also triggers the release of OT in the rat. The present study was aimed to evaluate the possible cardioprotective effects of endogenous OT released in response to stress (St), and effects of administration of exogenous OT on the ischemic-reperfused isolated heart of rats previously exposed to St. Wistar rats were divided into six groups: ischemia/reperfusion (IR); St: rats exposed to swim St for 10?min before anesthesia; St+atosiban (ATO): an OT receptor antagonist, was administered (1.5?mg/kg?i.p.) prior to St; St+OT: OT was administered (0.03?mg/kg?i.p.) prior to St; OT: OT was administrated prior to anesthesia; ATO was given prior to anesthesia. Isolated hearts were perfused with Krebs buffer solution by the Langendorff method and subjected to 30?min of regional ischemia followed by 60?min of reperfusion. The infarct size (IS) and creatine kinase MB isoenzyme (CK-MB) and lactate dehydrogenase (LDH) in coronary effluent were measured. Hemodynamic parameters were recorded throughout the experiment. The plasma concentrations of OT and corticosterone were significantly increased by St. Unexpectedly St decreased IR injury compared with the IR alone group. OT administration significantly inhibited myocardial injury, and administration of ATO with St abolished recovery of the rate pressure product, and increased IS and levels of CK-MB and LDH. These findings indicate that activation of cardiac OT receptors by OT released in response to St may participate in cardioprotection and inhibition of myocardial IR injury.     

On the evaporation kinetics of C60/toluene solutions

The increasing interest in fullerene nanoparticles makes the question regarding their effect on liquid evaporation behavior unavoidable. In this study, we used a gravimetric technique to investigate the effect of C₆₀ fullerene nanospheres on the evaporation kinetics of toluene over their entire range of solubility. Saturated solutions showed the highest evaporation rate. The increase in the evaporation rate as a function of concentration is not monotonic, but rather exhibits a maximum and a minimum. The results strongly support the notion of molecular structuring within the liquid toluene depending on fullerene mole fractions.