On the Ethics of Facial Transplantation Research

Transplantation continues to push the frontiers of medicine into domains that summon forth troublesome ethical questions. Looming on the frontier today is human facial transplantation. We develop criteria that, we maintain, must be satisfied in order to ethically undertake this as-yet-untried transplant procedure. We draw on the criteria advanced by Dr. Francis Moore in the late 1980s for introducing innovative procedures in transplant surgery. In addition to these we also insist that human face transplantation must meet all the ethical requirements usually applied to health care research. We summarize the achievements of transplant surgery to date, focusing in particular on the safety and efficacy of immunosuppressive medications. We also emphasize the importance of risk/benefit assessments that take into account the physical, aesthetic, psychological, and social dimensions of facial disfiguration, reconstruction, and transplantation. Finally, we maintain that the time has come to move facial transplantation research into the clinical phase.     

The role of autobiographical memory networks in the experience of negative emotions: how our remembered past elicits our current feelings

The present research examined the role of autobiographical memory networks on negative emotional experiences. Results from 2 studies found support for an active but also discriminant role of autobiographical memories and their related networked memories on negative emotions. In addition, in line with self-determination theory, thwarting of the psychological needs for competence, autonomy, and relatedness was found to be the critical component of autobiographical memory affecting negative emotional experiences. Study 1 revealed that need thwarting in a specific autobiographical memory network related to the theme of loss was positively associated with depressive negative emotions, but not with other negative emotions. Study 2 showed within a prospective design a differential predictive validity between 2 autobiographical memory networks (an anger-related vs. a guilt-related memory) on situational anger reactivity with respect to unfair treatment. All of these results held after controlling for neuroticism (Studies 1 and 2), self-control (Study 2), and for the valence (Study 1) and emotions (Study 2) found in the measured autobiographical memory network. These findings highlight the ongoing emotional significance of representations of need thwarting in autobiographical memory networks.     

Impact of situational legitimacy and assertiveness-related anxiety/discomfort on motivation and ability to generate effective criticism responses

This study compares the motivation and the quality of criticism responses of 697 undergraduates who were divided into three levels of situation legitimacy (high, moderate, and low) and two levels (top versus bottom 40 percent) of anxiety related to previous generalized assertiveness behaviours. The impact of gender was also studied. The results showed the legitimacy of the situation for a critical response (preassessed with peer hold-out groups) significantly affected participants' motivation to criticize as well as the quality of their critical responses, notwithstanding the poor quality of all criticism responses. Anxiety related to previous global assertiveness was related to high motivation but not to quality of criticism responses. There were no gender effects. Results are interpreted within an avoidance learning paradigm wherein the connotative meaning of criticism is incongruent with harmonious long-term relationships so that it is suppressed until virtually forced by the specifics of highly legitimate situations.