How does a child solve 7 + 8? Decoding brain activity patterns associated with counting and retrieval strategies

Cognitive development and learning are characterized by diminished reliance on effortful procedures and increased use of memory-based problem solving. Here we identify the neural correlates of this strategy shift in 7-9-year-old children at an important developmental period for arithmetic skill acquisition. Univariate and multivariate approaches were used to contrast brain responses between two groups of children who relied primarily on either retrieval or procedural counting strategies. Children who used retrieval strategies showed greater responses in the left ventrolateral prefrontal cortex; notably, this was the only brain region which showed univariate differences in signal intensity between the two groups. In contrast, multivariate analysis revealed distinct multivoxel activity patterns in bilateral hippocampus, posterior parietal cortex and left ventrolateral prefrontal cortex regions between the two groups. These results demonstrate that retrieval and counting strategies during early learning are characterized by distinct patterns of activity in a distributed network of brain regions involved in arithmetic problem solving and controlled retrieval of arithmetic facts. Our findings suggest that the reorganization and refinement of neural activity patterns in multiple brain regions plays a dominant role in the transition to memory-based arithmetic problem solving. Our findings further demonstrate how multivariate approaches can provide novel insights into fine-scale developmental changes in the brain. More generally, our study illustrates how brain imaging and developmental research can be integrated to investigate fundamental aspects of neurocognitive development.     

Dispositional variables and work–family conflict: A meta-analysis

Meta-analysis was used to comprehensively summarize the relationship between dispositional variables and both directions of work–family conflict. The largest effects detected were those associated with negative affect, neuroticism, and self-efficacy; all were in expected directions. In general, negative trait-based variables (e.g., negative affect and neuroticism) appear to make individuals more vulnerable to work–family conflict, while positive trait-based variables (e.g., positive affect and self-efficacy) appear to protect individuals from work–family conflict. In addition, the different dimensions of work–family conflict (time, strain, and behavior) exhibited different patterns of relationships with several of the dispositional variables. No moderating effects were found for sex, parental status, or marital status. Results support the notion that dispositions are important predictors of work–family conflict.     

Power,defensive denigration,and the assuaging effect of gratitude expression

This article examines the interactive effects of power, competency threats, and gratitude expression on the tendency to denigrate others. The results of two experiments indicate that (1) power holders whose competence has been threatened are more likely than others to denigrate interaction partners, and (2) receiving gratitude expression has self-affirming effects for insecure power holders. Experiment 1 demonstrated that high-power, but not low-power, individuals who received threatening feedback about their competence denigrated the competence of their partners. Importantly, this tendency was ameliorated when subordinates expressed gratitude for previous help provided from the power holder. Experiment 2 demonstrated that the ameliorating effect of gratitude expression on threatened power holders' tendency to denigrate subordinates is mediated by increased perceptions of social worth. Implications for research on power, gratitude expression, and the self are discussed.     

Views of Genetics Health Professionals on the Return of Genomic Results

As exome and whole genome sequencing become clinically available, the potential to receive a large number of clinically relevant but incidental results is a significant challenge in the provision of genomic counseling. We conducted three focus groups of a total of 35 individuals who were members of ASHG and/or NSGC, assessing views towards the return of genomic results. Participants stressed that patient autonomy was primary. There was consensus that a mechanism to return results to the healthcare provider, rather than patient, and to streamline integration into the electronic health record would ensure these results had the maximal impact on patient management. All three focus groups agreed that pharmacogenomic results were reasonable to return and that they were not felt to be stigmatizing. With regard to the return of medically relevant results, there was much debate. Participants had difficulty in consistently assigning specific diseases to ‘bins’ that were considered obligatory versus optional for disclosure. Consensus was reached regarding the importance of informed consent and pretest counseling visits to clarify what the return of results process would entail. Evidence based professional guidelines should continue to be developed and regularly revised to assist in consistently and appropriately providing genomic results to patients.     

Congruency sequence effect without feature integration and contingency learning

The magnitude of congruency effects, such as the flanker-compatibility effects, has been found to vary as a function of the congruency of the previous trial. Some studies have suggested that this congruency sequence effect is attributable to stimulus and/or response priming, and/or contingency learning, whereas other studies have suggested that the control process triggered by conflict modulates the congruency effect. The present study examined whether sequential modulation can occur without stimulus and response repetitions and contingency learning. Participants were asked to perform two color flanker-compatibility tasks alternately in a trial-by-trial manner, with four fingers of one hand in Experiment 1 and with the index and middle fingers of two hands in Experiment 2, to avoid stimulus and response repetitions and contingency learning. A significant congruency sequence effect was obtained between the congruencies of the two tasks in Experiment 1 but not in Experiment 2. These results provide evidence for the idea that the sequential modulation is, at least in part, an outcome of the top-down control process triggered by conflict, which is specific to response mode.     

Acting Superior But Actually Inferior?: Correlates and Consequences of Workplace Arrogance

Accounts of arrogant employees abound, yet there is little systematic research on arrogance within organizations. In response to this oversight, this article presents the findings from four studies. In Studies 1 and 2, the authors developed the Workplace Arrogance Scale and found support for its convergent and discriminant validity. In Study 3, the Workplace Arrogance Scale was included as part of a 360-degree performance feedback survey. Results revealed that there was satisfactory agreement between self- and other-ratings of arrogance. The authors also found that arrogance was negatively related to self- and other-rated task performance. Findings from Study 4 suggested that arrogance is negatively related to cognitive ability and self-esteem. The authors conclude by discussing the theoretical and practical implications of these findings.     

Accelerating heterogeneous nucleation to increase hardness and electrical conductivity by deformation prior to ageing for Cu-4 at.% Ti alloy

ABSTRACT

Deformation bands, especially shear bands were intentionally formed in supersaturated Cu-4 at.% Ti alloy by groove-rolling with 75% area reduction. Cold deformation prior to the ageing process changed the precipitation behaviour of the alloy. The deformed structure with shear bands was maintained, without showing recovery and recrystallisation, even after prolonged ageing at 450°C for more than one day. The thermally stable shear bands act as nucleation initiation sites and prevent the expansion of discontinuous cellular precipitates. The hardness reached a value of 305?Hv and an electrical conductivity of 15% IACS (IACS?=?International Annealed Copper Standard. 100% IACS is defined as the conductivity corresponding to a volume resistivity at 20°C of 17.241?nΩ), compared to 283?Hv and 13% IACS for conventional solid-solutioned and peak-hardened alloy. In addition, the ageing time to reach the highest hardness was shortened from 720 to 180?min at 450°C.     

Cultural differences in the development of processing speed

The aim of the present work was to examine cultural differences in the development of speed of information processing. Four samples of US children (N = 509) and four samples of East Asian children (N = 661) completed psychometric measures of processing speed on two occasions. Analyses of the longitudinal data indicated that, although processing speed was comparable among US and East Asian children at the youngest age (~4.5 years), it developed more rapidly in some but not all of the East Asian samples. Results are discussed in terms of factors that may promote more rapid development of processing speed in some East Asian cultures.     

ELSI Priorities for Brain Imaging

As one of the most compelling technologies for imaging the brain, functional MRI (fMRI) produces measurements and persuasive pictures of research subjects making cognitive judgments and even reasoning through difficult moral decisions. Even after centuries of studying the link between brain and behavior, this capability presents a number of novel significant questions. For example, what are the implications of biologizing human experience? How might neuroimaging disrupt the mysteries of human nature, spirituality, and personal identity? Rather than waiting for an ethical agenda to emerge from some unpredictable combination of the concerns of ethicists and researchers, the attention of journalists, or after controversy is sparked by research that cannot be retracted, we queried key figures in bioethics and the humanities, neuroscience, media, industry, and patient advocacy in focus groups and interviews. We identified specific ethical, legal and social issues (ELSI) that highlight researcher obligations and the nonclinical impact of the technology at this new frontier.     

Pilot study of hormone replacement therapy and menopausal symptoms, depression, and quality of life in Korean climacteric women

This cross-sectional survey compared scores on the Menopausal Symptoms Index, Depression, and the Quality of Life for 65 Korean climacteric women receiving regular hormone replacement therapy (M age=52.8 yr., SD=6.3) and 70 Korean climacteric patients not receiving such therapy (M age =51.6 yr., SD=7.1). Depression scores were positively correlated with the Menopausal Symptoms Index in both groups (r = .58 in the Therapy group and r = .50 in the Control group) and negatively correlated with scores for Quality of Life (r = -.48 in the Therapy group and r = -.68 in the Control group). Scores on the Menopausal Symptoms Index were negatively correlated with ratings of Quality of Life in both groups (r = -.53 in the Therapy group and r = -.45 in the Control group). These results suggest that hormone replacement therapy is associated with reduced Depression scores and higher Quality of Life scores in this sample of Korean climacteric women.