Representational momentum and the brain: An investigation into the functional necessity of V5/MT

The mental representation of objects can imply motion and momentum. This can be explored by investigating a distortion in recognition memory for pictures that depict objects “frozen” in mid-air, implying motion. This distortion is called representational momentum (RM). Recent functional neuroimaging studies have suggested that the V5/MT system (the area of the brain thought to be responsible for perceptual processing of motion) is involved in the mediation of RM. The results of these studies are reviewed here. However the presence of functional activity revealed in brain imaging studies does not mean that this part of the brain is necessary for a particular cognitive task. A greater degree of functional necessity can be inferred by disrupting function in that part of the brain. One way in which this can be done is with Transcranial Magnetic Stimulation (TMS, a method of temporarily suspending cortical activity). We extended the findings of the previous fMRI experiments by using TMS in conjunction with an RM paradigm. Repetitive magnetic stimulation to V5/MT during the so-called freeze-frame RM task resulted in an absence of the stereotypical distortion in recognition memory (compared to stimulation at the vertex) for approximately 60% of     

Developmental and sex-related differences in preschoolers' affective decision making

This study investigated developmental and sex-related differences in affective decision making, using a two-deck version of Children's Gambling Task administered to 3- and 4-year-old children. The main findings were that 4-year-old children displayed better decision-making performance than 3-year-olds. This effect was independent of developmental changes in inductive reasoning, language, and working memory. There were also sex differences in decision-making performance, which were apparent only in 3-year-old children and favored girls. Moreover, age predicted awareness of task and the correlation between the latter and decision-making performance was significant, but only in 4-year-old children. This study thus indicates that there is a remarkable developmental leap in affective decision making, whose effects are apparent around the age of 4, which according to our results, also marks the age when the correlation of declarative knowledge and decision-making performance becomes significant.     

Coarse threat images reveal theta oscillations in the amygdala: A magnetoencephalography study

Neurocognitive models propose a specialized neural system for processing threat-related information, in which the amygdala plays a key role in the analysis of threat cues. fMRI research indicates that the amygdala is sensitive to coarse visual threat relevant information—for example, low spatial frequency (LSF) fearful faces. However, fMRI cannot determine the temporal or spectral characteristics of neural responses. Consequently, we used magnetoencephalography to explore spatiotemporal patterns of activity in the amygdala and cortical regions with blurry (LSF) and normal angry, fearful, and neutral faces. Results demonstrated differences in amygdala activity between LSF threat-related and LSF neutral faces (50–250 msec after face onset). These differences were evident in the theta range (4–8 Hz) and were accompanied by power changes within visual and frontal regions. Our results support the view that the amygdala is involved in the early processing of coarse threat related information and that theta is important in integrating activity within emotion-processing networks.     

The association of paternal mood and infant temperament: A pilot study

Maternal depression is associated with adverse child development, but little is known about the effects of paternal depression. This pilot study estimated the prevalence of paternal depression and mood state, and assessed the relationship between paternal mood and infant temperament. The participants in the study were 98 fathers of newborn babies. Fathers were initially screened for depressed mood (Hospital anxiety and depression scale, and Edinburgh postnatal depression scale), and at 6 months parental mood, infant temperament, couple relationship quality, alcohol use, adverse life events, parenting, and demographics were recorded. Infant fussiness was analysed in relation to paternal mood and other contextual factors using multiple regression. Of the 98 fathers, 48 (49%) completed depression-screening measures. Of these 48 fathers, 4 (8%) reported depressive symptoms above the cut-off for case definition. A total of 48% (N=19) completed measures at follow-up. In the adjusted model, higher paternal depression scores, more traditional attitudes towards fathering, and increased recent life events were related to higher infant fussiness scores; and better couple relationship quality was related to lower fussiness scores. This study showed that 1 in 12 fathers had depressed mood, and lower mood was associated with negative infant temperament. Since the findings of this feasibility study were based on a small sample size the association of paternal mood and child development merits further study using a larger sample of fathers.     

Kasuistik einer adoleszenten Frau mit NMDA-Rezeptor-antikörperpositiven Enzephalitis

Paraneoplastic encephalitis, an immune-mediated disease, has been known for a long time. In the last decade, several specific antibodies against cell membrane-located antigens causing limbic or diffuse encephalitis have been identified. Most of these cases are in fact non-paraneoplastic. These antibodies are likely primarily involved in the pathogenesis, in contrast to antineuronal antibodies against cytoplasmatic antigens (e.g., anti-Hu, anti-Yo, and anti-Ma2), which are more likely an epiphenomenon. The case reported here is an adolescent woman presenting with NMDAR (N-methyl D-aspartate receptor) antibody encephalitis, finally diagnosed during a relapse. The diagnostic and therapeutic approach to NMDAR antibody and limbic encephalitis is discussed.     

The Bender-Gestalt test in differential diagnosis of adolescents with learning difficulties

This study assessed the efficiency of the Haine and Koppitz scoring systems used with the Bender-Gestalt Test (B-G) in terms of their ability to differentiate between adolescents with and without central nervous system (CNS) impairment who were achieving below age-expectations. Utilizing a population of 84 adolescents enrolled in a residential treatment center, both the Haine and Koppitz systems with the Bender-Gestalt differentiated 25 Ss with CNS impairment from 59 Ss wihout such impairment. The results indicated, however, that neither scoring system was useful in individual classification when the B-G was used alone or in combination with intelligence test results.     

Individual Quality of Life Among at Risk Indigenous Youth in Australia

This paper reports the findings from a pilot study in which the Schedule for Individual Quality of Life (SEIQoL-DW) was used to determine how 15 at-risk Indigenous Australian male youths aged between 14 and 19 conceptualised their quality of life. The youths, who were referred with problems associated with drug and alcohol misuse and criminal activity, were attending a diversionary program run by an Indigenous organisation in the Northern Territory, Australia. Quality of life was measured before and at the end of the nine-day programme in order to evaluate outcomes. Program staff found the SEIQoL-DW to be particularly useful in identifying culturally specific quality of life domains, allowing interventions to focus on improving the life areas that were of particular value to individuals as well as recognizing any deficits in their understanding the options available to them. While a control group was not used, mean SEIQoL-DW scores increased significantly over the course of the program.