Pediatric Whole Exome Sequencing: an Assessment of Parents’ Perceived and Actual Understanding.

Whole exome sequencing (WES) is an integral tool in the diagnosis of genetic conditions in pediatric patients, but concerns have been expressed about the complexity of the information and the possibility for secondary findings that need to be conveyed to those deciding about WES. Currently, there is no validated tool to assess parental understanding of WES. We developed and implemented a survey to assess perceived and actual understanding of WES in parents who consented to clinical WES for their child between July 2013 and May 2015. Fifty-three eligible surveys were returned (57% response rate). Areas with both low perceived and actual understanding about WES included how genes are analyzed and lack of protection against life insurance discrimination. Parents also had low actual understanding for two questions related to secondary findings – reporting of secondary findings in a parent (if tested) and whether secondary findings can be related to traits such as height and hair color. Further work to develop a validated tool to assess understanding of WES would be beneficial as WES is integrated more frequently into clinical care.     

The effects of feedback self-consistency, therapist status, and attitude toward therapy on reaction to personality feedback

Individuals' reactions to interpersonal feedback may depend on characteristics of the feedback and the feedback source. The present authors examined the effects of experimentally manipulated personality feedback that they--in the guise of therapists--e-mailed to participants on the degree of their acceptance of the feedback. Consistent with Self-Verification Theory (W. B. Swann Jr., 1987), participants accepted feedback that was consistent with their self-views more readily than they did feedback that was inconsistent with their self-views. Furthermore, the authors found main effects for therapist's status and participant's attitude toward therapy. Significant interactions showed effects in which high-status therapists and positive client attitudes increased acceptance of self-inconsistent feedback, effects that were only partially mediated by clients' perceptions of therapist competence. The present results indicate the possibility that participants may be susceptible to self-concept change or to self-fulfilling prophecy effects in therapy when they have a positive attitude toward therapy or are working with a high-status therapist.     

What Predicts the Use of Genetic Counseling Services After the Birth of a Child with Down Syndrome?

In the state of Victoria, Australia, a government funded genetic counseling service exists to meet the needs of families. An audit showed that many families do not use this service after the birth of a child with a genetic problem. To investigate this we surveyed families of children born with Down syndrome over 2 years in Victoria. Questionnaires were completed by 74 mothers, of whom only 18 had received genetic counseling between the birth and the time of the study (mean 3.5 years). Of those not receiving genetic counseling, 71% said they were not offered or had not heard of it. Mothers who had genetic counseling were younger than those who had not, and were more likely to have attended University. Those who had genetic counseling indicated less satisfaction with care at the diagnosis and were more likely to perceive their child as unwell at birth than those who were aware of genetic counseling but did not have it. Of those who did not have genetic counseling, over half were unclear about what it is, although 74% agreed with the statement genetic counseling is most useful when planning to have another child. Of those who had heard of genetic counseling, 73% said they were not sure how it could help. Many families with children with Down syndrome are not aware of the existence or functions of genetic counseling. With greater awareness, some may still choose not to have genetic counseling, but others enunciated needs that could be met by this service if it were offered to them.     

Motivations for caregiving in adult intimate relationships: influences on caregiving behavior and relationship functioning

This study identified and examined the correlates of specific motivations for caregiving in romantic couples (N = 194 couples). At Time 1, couple members completed measures assessing motivations for caregiving, the quality of caregiving that occurs in the relationship, and personal and relationship characteristics that might influence caregiving motivations. Relationship functioning was then assessed 2 to 3 months later. Results revealed that (a) there are a number of distinct motivations for providing and for not providing care to one's partner, (b) the motivations are associated with various personal features of the caregiver and the recipient, (c) the caregiver's perceptions of the relationship influence his or her caregiving motives, (d) different motivations for caregiving predict different patterns of caregiving behavior, and (e) responsive caregiving predicts the recipient's perceptions of healthy relationship functioning both immediately and over time. Implications of identifying the motivations that promote or inhibit the provision of responsive support in intimate relationships are discussed.     

The embodiment of reconciliation: order and change in the work of Frederic Bartlett

Frederic Bartlett (1886-1969) was one of the most prominent figures in British academic psychology during the 20th century. His psychological work has had a mixed reception, but there is no doubt that it continues to be much cited. Bartlett and his work have also attracted considerable historical attention both within history of ideas accounts and in attempts to understand the establishment of British academic psychology. The present article argues that new light can be shed on Bartlett's writings by seeing them as repeatedly grappling with 2 interrelated themes: the preservation of order and the adjustment to changing conditions. The article illustrates the ways in which these themes ran through his major works and informed some of his key theoretical concepts before going on to examine some of the potential sources for these themes.     

Summation in causal learning: elemental processing or configural generalization?

Results from human causal learning tasks that employ multiple cues are often interpreted in terms of the elemental theory of Rescorla and Wagner (1972). However, most results can also be successfully interpreted by the configural model proposed by Pearce (1987, 1994). One method of discriminating between these alternatives is through an investigation of summation and overexpectation. Indeed, demonstrations of these phenomena are fundamental to an elemental approach but are generally incompatible with an account that involves configural processing. Using a procedure in which the magnitude of the outcome varied, evidence for both summation and overexpectation was obtained in two experiments.     

The Effects Of Recruitment Message Specificity On Applicant Attraction To Organizations

We used the elaboration likelihood model (ELM) from marketing research to explain and examine how recruitment message specificity influences job seeker attraction to organizations. Using an experimental design and data from 171 college-level job seekers, the results showed that detailed recruitment messages led to enhanced perceptions of organization attributes and person–organization (P–O) fit. Perceptions of fit were found to mediate the relationship between message specificity and intention to apply to the organization. In addition, perceptions of organization attributes and P–O fit were found to influence intentions to apply under circumstances of explicit recruitment information while attractiveness and fit perceptions were shown to influence application intentions under conditions of implicit recruitment information. The theoretical and practical implications of these findings are discussed.     

Race and ethnicity in the genome era: the complexity of the constructs

The vast amount of biological information that is now available through the completion of the Human Genome Project presents opportunities and challenges. The genomic era has the potential to advance an understanding of human genetic variation and its role in human health and disease. A challenge for genomics research is to understand the relationships between genomics, race, and ethnicity and the implications of uncovering these relationships. Robust and scholarly discourse on the concept of race and ethnicity in genomic research should be expanded to include social and behavioral scientists. Interdisciplinary research teams are needed in which psychologists, as well as other social and behavioral scientists, work collaboratively with geneticists and other natural scientists.     

Contemporary research on parenting. The case for nature and nurture

Current findings on parental influences provide more sophisticated and less deterministic explanations than did earlier theory and research on parenting. Contemporary research approaches include (a) behavior-genetic designs, augmented with direct measures of potential environmental influences; (b) studies distinguishing among children with different genetically influenced predispositions in terms of their responses to different environmental conditions; (c) experimental and quasi-experimental studies of change in children's behavior as a result of their exposure to parents' behavior, after controlling for children's initial characteristics; and (d) research on interactions between parenting and nonfamilial environmental influences and contexts, illustrating contemporary concern with influences beyond the parent-child dyad. These approaches indicate that parental influences on child development are neither as unambiguous as earlier researchers suggested nor as insubstantial as current critics claim.