Obstructive Sleep Apnea Syndrome in Prader-Willi Syndrome: An Unrecognized and Untreated Cause of Cognitive and Behavioral Deficits?

Prader-Willi Syndrome (PWS) is a rare genetic disorder characterized by a range of physical, psychological, and physiological abnormalities. It is also distinguished by the high prevalence of obstructive sleep apnea syndrome (OSAS), i.e., repetitive upper airway collapse during sleep resulting in hypoxia and sleep fragmentation. In non-PWS populations, OSAS is associated with a range of neurocognitive and psychosocial deficits. Importantly, these deficits are at least partly reversible following treatment. Given the findings in non-PWS populations, it is possible that OSAS may contribute to neurocognitive and psychosocial deficits in PWS. The present review examines this possibility. While acknowledging a primary contribution from the primary genetic abnormality to central neural dysfunction in PWS, we conclude that OSAS may be an important secondary contributing factor to reduced neurocognitive and psychosocial performance. Treatment of OSAS may have potential benefits in improving neurocognitive performance and behavior in PWS, but this awaits confirmatory investigation.     

Spreading activation or spooky action at a distance?

How do preexisting connections among a word's associates facilitate its cued recall and recognition? A spreading-activation model assumes activation spreads to, among, and from a studied word's associates, and that its return is what strengthens its representation. An activation-at-a-distance model assumes strengthening is produced by the synchronous activation of the word's associates. The spread model predicts that connections among the studied word's associates will have a greater effect on memory when more of its associates return activation. The distance model predicts that total connections are important, not their direction. The results of cued recall experiments supported the distance model in showing that that connections among the associates facilitated recall regardless of the number of returning connections.     

Are implicitly activated associates selectively activated?

What constitutes a word’s associative past? Words differ in how many associates they activate in memory and, following a brief encounter, those with fewer associates are more likely to be recalled in the presence of related cues. The issue addressed in the present article is whether associative set size effects are produced through the selective activation of strong associates or through the activation of both strong and weak associates. The set size of the strongest associates was varied factorially with the set size of the associates of these associates. We assume that associate set size indexes a word’s weaker associates. Experiments 1 and 2 showed that recall varied inversely with both target and associate set sizes. Such results held over variations in study time and participant age. Experiment 3 showed that weak associates of the target had a greater effect on recall when there were more connections among the strongest associates in the set. The findings suggest that activation is not strength selective but includes both weak and strong associates.     

Husserl's phenomenological discovery of the natural attitude

In this paper I will give a systematic account of Husserl's notion of the natural attitude in the development from its first presentation in Ideas I (1913) until Husserl's last years. The problem of the natural attitude has to be dealt with on two levels. On the thematic level, it is constituted by the correlation of attitude and horizon, both stemming from Husserl's theory of intentionality. On the methodic level, the natural attitude is constituted by three factors: naturalness, naivety and normality. I shall conclude by sketching out a possible motivation for leaving the natural attitude and thus for entering the sphere of phenomenology.     

Immediate and delayed effects of victim suffering on the attacker's aggression

On the first day of a two-day experiment, male undergraduates were either angered or not, and they were given either high, low, or no metered pain feedback after each shock they supposedly delivered to their previous evaluator for his errors on a learning task. After the learning task the subjects made a number of ratings, including how much they had enjoyed this first session. On the second day, all subjects were simply required to administer shocks to a different person for his mistakes on the same learning task. The angered subjects were more punitive on both days toward both learners than the nonangered men. On the first day the angered men also increased the intensity of the shocks they delivered over trial blocks. Most interestingly, the angered men showed more enjoyment of the first session of the experiment as their victim's pain increased, and this enjoyment rating was related to the angered subjects' level of aggression on the second day of the experiment when they punished an “innocent” victim. The results were interpreted as consistent with the hypothesized reinforcement process which essentially states that signs and/or knowledge of the victim's suffering can reinforce impulsive or angry aggressive behavior.     

Issues in common law pleading and ancient rhetoric

The concepts of issue and status are more different than is currently assumed. Apart from differences between the classifications of statements they are related to, there are differences between their definitions. The respective functions of pleadings and of inventio account for most of these differences.     

Retrieval processes in perceptual recognition and cued recall: The influence of category size

The purpose of these experiments was to determine whether nonsemantic category size and other variables would influence perceptual recognition as they influence cued recall. Procedures developed by Jacoby and his associates were replicated with words belonging to either small or large nonsemantic categories and with recognition tested under bright-target/patterned-mask conditions. The results indicated that words belonging to larger nonsemantic sets were more difficult to identify. This finding and the results of other manipulations are discussed in relation to the interactive activation model and to the proposal that perceptual recognition performance is dependent on a retrieval process similar to that involved in recall prompted by nonsemantic cues.