Effectiveness of a responsible conduct of research course: a preliminary study

Training in the responsible conduct of research (RCR) is required for many research trainees nationwide, but little is known about its effectiveness. For a preliminary assessment of the effectiveness of a short-term course in RCR, medical students participating in an NIH-funded summer research program at the University of California, San Diego (UCSD) were surveyed using an instrument developed through focus group discussions. In the summer of 2003, surveys were administered before and after a short-term RCR course, as well as to alumni of the courses given in the summers of 2002 and 2001. Survey responses were analyzed in the areas of knowledge, ethical decision-making skills, attitudes about responsible conduct of research, and frequency of discussions about RCR outside of class. The only statistically significant improvement associated with the course was an increase in knowledge, while there was a non-significant tendency toward improvements in ethical decision-making skills and attitudes about the importance of RCR training. The nominal impact of a short-term training course should not be surprising, but it does raise the possibility that other options for delivering information only, such as an Internet-based tutorial, might be considered as comparable alternatives when longer courses are not possible.     

Heterophenomenology: Heavy-handed sleight-of-hand

We argue that heterophenomenology both over- and under-populates the intentional realm. For example, when one is involved in coping, one’s mind does not contain beliefs. Since the heterophenomenologist interprets all intentional commitment as belief, he necessarily overgenerates the belief contents of the mind. Since beliefs cannot capture the normative aspect of coping and perceiving, any method, such as heterophenomenology, that allows for only beliefs is guaranteed not only to overgenerate beliefs but also to undergenerate other kinds of intentional phenomena.     

An in-situ examination of the timing of information pick-up for interception by cricket batsmen of different skill levels

ObjectivesCricket batting is performed under demanding constraints, which requires rapid and accurate decision making for successful achievement of the skill goal. To understand how batsmen negotiate these constraints, the capability of highly skilled and low skilled cricket batsmen to utilise visual information prior to and during sections of ball flight to strike balls delivered by fast bowlers was examined.MethodSix highly skilled and six low skilled batsmen faced different types of balls delivered by three fast bowlers. Batsmen wore vision occlusion spectacles and were required to strike delivered balls, while their vision of the bowler's delivery action and ball flight was selectively occluded. Three vision conditions were randomly designed that included temporal occlusion at: (i) a point prior to ball release (providing only advance information), (ii) a point prior to ball bounce (providing advance and ball flight information) and (iii) no occlusion (where all advance, ball flight and bounce information were visible). Foot movements made forward or backward were assessed as a measure of ball length judgement, while the quality of bat–ball contact was assessed as a measure of interception.ResultsResults demonstrated the superior capability of highly skilled batsmen to utilise information prior to ball release to judge short ball length. Expert batsmen were better able to utilise ball flight information prior to and post-bounce to attain a superior number of bat–ball contacts.ConclusionsFindings demonstrate that the mechanism of experts to deal with task constraints when attempting to intercept a delivered ball is their capability to pick-up visual information to judge ball landing position.     

Prolonging life and delaying death: The role of physicians in the context of limited intensive care resources

In the past decade donor commitments to health have increased by 200 percent. Correspondingly, there has been a swell of new players in the global health landscape. The unprecedented, global response to a single disease, HIV/AIDS, has been responsible for a substantial portion of this boon. Numerous health success have followed this windfall of funding and attention, yet the food, fuel, and economic crises of 2008 have shown the vulnerabilities of health and development initiatives focused on short term wins and reliant on a constant flow of foreign funding. For too long, the international community has responded to global health and development challenges with emergency solutions that often reflect the donor's priorities, values, and political leanings, rather than funding durable health systems that can withstand crises. Progress towards achieving the Millennium Development Goals has stalled in many countries. Disease specific initiatives have weakened health systems and limited efforts to improve maternal and child health. As we enter this era of scarce resources, there is a need to return to the foundations of the Alma Ata Declaration signed thirty years ago with the goal of providing universal access to primary healthcare. The global health community must now objectively evaluate how we can most effectively respond to the crises of 2008 and take advantage of this moment of extraordinary attention for global health and translate it into long term, sustainable health improvements for all.     

Prolonging life and delaying death: The role of physicians in the context of limited intensive care resources

Critical care is in an emerging crisis of conflict between what individuals expect and the economic burden society and government are prepared to provide. The goal of critical care support is to prevent suffering and premature death by intensive therapy of reversible illnesses within a reasonable timeframe. Recently, it has become apparent that early support in an intensive care environment can improve patient outcomes. However, life support technology has advanced, allowing physicians to prolong life (and postpone death) in circumstances that were not possible in the recent past. This has been recognized by not only the medical community, but also by society at large. One corollary may be that expectations for recovery from critical illness have also become extremely high. In addition, greater numbers of patients are dying in intensive care units after having receiving prolonged durations of life-sustaining therapy. Herein lies the emerging crisis – critical care therapy must be available in a timely fashion for those who require it urgently, yet its provision is largely dependent on a finite availability of both capital and human resources. Physicians are often placed in a troubling conflict of interest by pressures to use health resources prudently while also promoting the equitable and timely access to critical care therapy. In this commentary, these issues are broadly discussed from the perspective of the individual clinician as well as that of society as a whole. The intent is to generate dialogue on the dynamic between individual clinicians navigating the complexities of how and when to use critical care support in the context of end-of-life issues, the increasing demands placed on finite critical care capacity, and the reasonable expectations of society.     

Circadian modulation of conditioned place avoidance in hamsters does not require the suprachiasmatic nucleus

Animals possess the ability to remember both the time of day as well as the location that noxious and potentially dangerous conditions occur. A behavioral expression of this learning is demonstrated in conditioned place avoidance (CPA). CPA is strongest when the time of testing matches the time of day that the prior training had occurred, suggesting the involvement of a circadian oscillator that modulates either memory retrieval or reactivity to the conditioned environment. In these experiments we show that time of day learning persists in the absence of the central circadian clock in the suprachiasmatic nucleus (SCN), demonstrating that memory for time of day is implicit in context conditioning and may involve a circadian oscillator that is distinct from the SCN.     

Perceptual Demonstrative Thought: A Property-Dependent Theory

Topoi - The paper presents a new theory of perceptual demonstrative thought, the property-dependent theory. It argues that the theory is superior to both the object-dependent theory (Evans,...