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111.
Masand PS Culpepper L Henderson D Lee S Littrell K Newcomer JW Rasgon N 《CNS spectrums》2005,10(10):suppl14 1-suppl1415
Patients with psychiatric disorders have an increased rate of cardiovascular morbidity and mortality compared with the general population. Metabolic issues such as weight gain, dyslipidemia, diabetes mellitus, diabetic ketoacidosis,and pancreatitis have been reported with the use of antipsychotic agents. Although atypical antipsychotics have not been linked directly to the development of metabolic syndrome, these medications have been shown to increase risk factors that can lead to metabolic and endocrine disturbances. Therefore, clinicians should provide ongoing monitoring for patients who are being treated for psychiatric disorders with these agents. According to the 2004 Consensus Report on Antipsychotics, screening measures should include baseline and follow-up monitoring of personal/family histories, weight (body mass index), waist circumference, blood pressure, fasting plasma glucose, and fasting lipid profile. 相似文献
112.
Wigal SB McGough JJ McCracken JT Biederman J Spencer TJ Posner KL Wigal TL Kollins SH Clark TM Mays DA Zhang Y Tulloch SJ 《Journal of attention disorders》2005,9(1):275-289
Mixed amphetamine salts extended release (MAS XR; Adderall XR) and atomoxetine (Strattera) were compared in children 6 to 12 years old with attention deficit/hyperactivity disorder (ADHD) combined or hyperactive/impulsive type in a randomized, double-blind, multicenter, parallel-group, forced-dose-escalation laboratory school study. Primary efficacy measure was the SKAMP (Swanson, Kotkin, Agler, M-Flynn, and Pelham) behavioral rating scale. Changes in mean SKAMP deportment scores from baseline were significantly greater for MAS XR (n = 102) than for atomoxetine (n = 101) overall (-0.56 and -0.13, respectively; p < .0001) and at each week (p < .001). Adverse events were similar for both treatment groups. The extended time course of action and greater therapeutic efficacy of MAS XR suggests that it is more effective than atomoxetine in children with ADHD. 相似文献
113.
Coleman SL Brown VR Levine DS Mellgren RL 《Cognitive, affective & behavioral neuroscience》2005,5(4):434-451
This article develops the cognitive—emotional forager (CEF) model, a novel application of a neural network to dynamical processes in foraging behavior. The CEF is based on a neural
network known as the gated dipole, introduced by Grossberg, which is capable of representing short-term affective reactions in a manner similar to Solomon
and Corbit’s (1974) opponent process theory. The model incorporates a trade-off between approach toward food and avoidance
of predation under varying levels of motivation induced by hunger. The results of simulations in a simple patch selection
paradigm, using a lifetime fitness criterion for comparison, indicate that the CEF model is capable of nearly optimal foraging
and outperforms a run-of-luck rule-of-thumb model. Models such as the one presented here can illuminate the underlying cognitive
and motivational components of animal decision making. 相似文献
114.
Robert JS 《The American journal of bioethics : AJOB》2005,5(3):27-9; discussion W4-9
115.
Two studies examined whether a criminal defendant's race influences Whites' sensitivity to legally relevant information. In Study 1, prosecution case strength ratings and guilt likelihood ratings were more sensitive to the strength of the defendant's alibi when he was Black than when he was White, if the experimental task was designed to elicit low processing motivation. Under high motivation, participants were equally sensitive to alibi strength, regardless of defendant race. In Study 2, the alibi strength manipulation was replaced with a manipulation of the effectiveness of the district attorney's cross-examination. As predicted, defense case strength ratings were more sensitive to the strength of the prosecutor's cross-examination with a Black defendant than with a White defendant-under low motivation. Under high motivation, sensitivity did not depend on defendant race. These results suggest that a Black defendant can elicit greater sensitivity to legally relevant information than will a White defendant. 相似文献
116.
Johnson SP 《Psychological science》2004,15(11):769-775
Perceptual completion consists of bridging the gaps imposed by occlusion, such as perceiving the unity of center-occluded objects. It is unknown at present what developmental mechanisms underlie the emergence of functional perceptual completion in infancy. One current debate centers on the role of visible surface motion. According to a core-principles account, perceptual completion emerges simultaneously with the onset of motion discrimination, the sole determinant of unity percepts in infants. According to a contrasting constructivist account, motion discrimination is but one of several independent inputs to perceptual completion. In the present study, 2-month-old infants were tested for both unity perception and motion discrimination in partial-occlusion displays. Motion discrimination obtained under all conditions, even under circumstances in which infants were unable to perceive completion. Four-month-olds showed marked improvements in perceptual completion, most likely because of improvements in information integration. Taken together, these findings support a constructivist view of early perceptual and cognitive development. 相似文献
117.
Using micro-video cameras attached to the heads of 2 dogs, we examined their optical behavior while catching Frisbees. Our findings reveal that dogs use the same viewer-based navigational heuristics previously found with baseball players (i.e., maintaining the target along a linear optical trajectory, LOT, with optical speed constancy). On trials in which the Frisbee dramatically changed direction, the dog maintained an LOT with speed constancy until it apparently could no longer do so and then simply established a new LOT and optical speed until interception. This work demonstrates the use of simple control mechanisms that utilize invariant geometric properties to accomplish interceptive tasks. It confirms a common interception strategy that extends both across species and to complex target trajectories. 相似文献
118.
119.
Maxwell SE 《心理学方法》2004,9(2):147-163
Underpowered studies persist in the psychological literature. This article examines reasons for their persistence and the effects on efforts to create a cumulative science. The "curse of multiplicities" plays a central role in the presentation. Most psychologists realize that testing multiple hypotheses in a single study affects the Type I error rate, but corresponding implications for power have largely been ignored. The presence of multiple hypothesis tests leads to 3 different conceptualizations of power. Implications of these 3 conceptualizations are discussed from the perspective of the individual researcher and from the perspective of developing a coherent literature. Supplementing significance tests with effect size measures and confidence intervals is shown to address some but not necessarily all problems associated with multiple testing. 相似文献
120.
Mio JS 《Cultural diversity & ethnic minority psychology》2004,10(1):90-94
The discussion of racial and ethnic minority issues has traditionally been a Black-White discussion. As such, American Indians, Latinos, and Asians have been left out of this discussion. Such exclusion does not make scientific sense, as it makes conclusions about race relations less generalizable. It also comes with a cost, as the excluded groups are often asked to give up their respective ethnicities to join the discussion. The present article, discusses some of these scientific and social losses and suggests that prominent African American and White leaders serve as allies for the inclusion of all groups in the discussion of race relations, focusing particularly on the Asian experience. Such allies must come not only from academicians but also from community activists and those in power positions in the media. 相似文献