Out-patient treatment of psychoses using depot-fluphenazin]

43 courses of treatment in various psychoses are reported. Peculiarities of dosage and application, and the position of Depot-Fluphenazin as compared to other Depot-neuroliptics are considered in detail.     

Frequency pattern of alpha waves in the early stages of cerebrovascular circulation disorders]

In this study 201 EEG curves are interpreted belonging to patients suffering from incipient disturbances of the cerebral circulation. The patients were divided into 3 groups according to age (group I, 30-40 years; group II, 40-50 years; group III, 50 years and over). In group I there prevailed a rate of 11-12 alpha waves per sec., and a slower rate was hardly ever found; in group III the frequency pattern was quite different. This decreased frequency of the waves could be confirmed by statistics. We believe a direct link can be assumed to exist between a decrease in frequency and the beginning of disturbed cerebral circulation.     

Stabilized images: Functional relationships among populations of orientation-specific mechanisms in the human visual system

Two experiments are presented in which fading rates of stabilized line stimuli were measured following prolonged adaptation to nonstabilized grating patterns in various orientations. Results indicated that some orientation-specific effects are sensitive to small variations of orientation around an optimal orientation, as well as to stimuli rotated 90 deg from the optimal orientation. These data were interpreted in terms of interactions among populations of orientation-specific mechanisms in the human visual system.     

Stabilized images: The search for pattern elements

In a series of four experiments, the fragmentation of stabilized lines and angles viewed in different orientations was studied. With high inter-O agreement, it was possible to demonstrate reliable differences among patterns, with resistance to fading being a function of both pattern and orientation. The results were discussed in terms of possible supraretinal stages of pattern analysis.     

Event-related potential studies of cerebral specialization during reading : II. Studies of congenitally deaf adults

A number of methodological features were incorporated in a paradigm designed to maximize the likelihood of finding reliable event-related potential (ERP) signs of functional specializations between and within the cerebral hemispheres. Every subject was more accurate in identifying words presented to the right than to the left visual field. The morphology of the ERPs elicited by these words varied considerably as a function of electrode position both within and between the hemispheres. Amplitude asymmetries of ERP components recorded from occipital regions of the two hemispheres varied systematically with the position of the word in the visual field. On the other hand, ERPs from more anterior (temporal and frontal) regions displayed large asymmetries which were in the same direction regardless of the visual field of word presentation. The most prominent such asymmetry was in the negativity in the region 300–500 msec (N410) which was larger in the left than the right hemisphere in every subject. These results demonstrate that in this paradigm which demands specialized language processing ERPs are sensitive to aspects of cerebral organization both within and between the two hemispheres.     

Observations of the course of patients with hyperkinesis

This article reports observations made on thirty-six patients suffering from oral dyskinesia (tardive dyskinesia). In thirty cases, dyskinesia was observed to occur in the course of neuroleptic therapy. Occurrence of dyskinesia was dependent upon the use of a higher dosage rather than upon the duration of medication. Persons showing dyskinesia were not always subjects with previous cerebral lesions or patients of advanced age. Of patients with schizoform diseases, those were usually affected with oral hyperkinesia who had either partly or completely lost the process symptomatology, but who were unable to live a life satisfying them in every respect.     

Hemispheric differences in tactile and visual recognition of braille-like stimulus patterns with static and dynamic modes of inspection

Summary Braille-like patterns were presented unilaterally to both tactual and visual modalities. The subject's task was to identify the location of three dots in a 2 × 3 six-dot pattern. Specifically, tactual versus visual presentation, dynamic versus static presentation of tactual stimuli, learning, and gender were examined in relation to cerebral hemisheric differences. Data were analyzed in terms of both the number of individual stimulus dots and the number of complete three-dot patterns correctly identified with regard to their spatial location. Although no reliable laterality differences were obtained with the tactual-static condition, owing to a significant interaction between learning and side of stimulus presentation, dot positions were reported reliably more accurately when presented in a dynamic fashion, i. e., scanned by the subject, to the right hand. For the visual modality, both correct reports of individual dot positions as well as correct reports of the entire patterns were reliably more accurate for stimulus presentations to the right visual field. Increased familiarity with the task, i. e., learning accross trials, generally increased report accuracy, particularly for static presentations to the left hand. The effect of gender was negligible. The results are dicussed in terms of their theoretical implications for differential cerebral hemispheric specializations in terms of differential processing strategies.The research reported here was supported by a Grant (A8621) from the Natural Sciences and Engineering Research Council of Canada to the second author. Offprint requests should be sent to Eugene C. Lechelt, Department of Psychology, University of Alberta, Edmonton, Alberta, Canada T6G 2E9