A method of determining unbiased distribution in the latin square

The paper describes a method of constructing Latin-square designs in which treatment sequences are unbiased with regard to serial order as well as position of treatment. The procedure is useful for those Latin squares in which the number of cells in each column (or row) is an even number, which, when written in ascending and descending series, contain corresponding ordered numbers prime to each other. Such numbers are 2, 4, 6, 10, 12, 16, 18, 22, 28, 30, 36, etc.     

Schedules using noxious stimuli. II: low intensity electric shock as a discriminative stimulus

The presence or absence of pulses of low intensity electric shock was used as a discriminative stimulus to control responding under fixed ratio reinforcement in the squirrel monkey. Initially brief periods of nonreinforcement were lengthened only when discriminative control was evident. Discriminative control was studied by (1) varying the duration of nonreinforcement periods; (2) reversing the stimulus conditions correlated with reinforcement and nonreinforcement periods; and (3) determining the minimum shock intensity necessary to maintain discriminative control. Stimulus control was not reliably affected by d-amphetamine, chlorpromazine, or morphine. The discriminative control by pulses of low intensity electric shock was similar to that by other discriminative stimuli, except that the control developed slowly and was better when the pulsing shock was correlated with reinforcement than when correlated with nonreinforcement.