Subtypes of psychopathology in children referred for neuropsychological assessment.

The validity of a Personality Inventory for Children-Revised edition (PIC-R) typology was examined in a sample of 323 children aged 6-16 years. These children had been referred to a children's mental health centre for neuropsychological assessment. In study 1, K-means cluster analysis (k = 12) was applied to the PIC clinical scales in an attempt to replicate the 12 clusters identified by Gdowski, Lachar, and Kline (1985). Partial cluster replication was achieved. Examination of the obtained clusters revealed significant overlap, suggesting that fewer clusters would represent an optimal solution. In study 2, a two-stage cluster analysis yielded a seven-cluster solution consistent with several key forms of psychopathology previously reported in the literature using specific neuropsychological populations. Identified subtypes included profiles characterized as: normal, cognitive deficit, cognitive deficit with internalized psychopathology, cognitive deficit with social impairment, cognitive deficit with hyperactivity, cognitive deficit with both internalized and externalized psychopathology, and combined internalized and externalized psychopathology without a cognitive deficit component.     

The Ecology of Adolescent Substance Abuse Service Utilization

This paper presents an ecological-community model toward the explanation of variation in patterns of substance abuse (SA) service utilization among adolescents who are enrolled in Tennessee's Medicaid program (TennCare). Guided by a theoretical framework that draws from the social ecology work of Bronfenbrenner and health services utilization models promoted by Aday and Andersen, we apply a social indicators approach toward explaining the impact of community ecology on identification of SA and treatment engagement. Both county-level rates and individual-level treatment utilization are examined and hierarchical linear modeling is incorporated to examine the individual-in-community phenomenon. This study is an expansion of previous service utilization research and suggests that explanations of youth's service utilization must necessarily include not only individual, familial, and service system characteristics, but community factors, as well.     

医院公共空间环境对病人心理的影响分析

医院公共空间设置应契合使用者对医院总体空间的使用需求,分析其心理、生理和行为特点,满足病人生理、心理和行为的需求。充分考虑病人对空间环境的响应度,对不同空间类型应提供多样支持,关注空间环境对病人的生理、心理和行为的影响,顺应医疗流程,防止和控制交叉感染。     

Nursing students’ reflections on an interprofessional placement in ambulatory care

Reflection has been identified as key to interprofessional education as it facilitates a focus on interprofessional communication, collaborative practice and professional roles, while contributing to debunking ingrained understandings of roles and behaviours. The aim of this study is to explore the written reflections of nursing students following an interprofessional placement in ambulatory care. A deductive analysis of nursing student reflective journal entries mapped against the university interprofessional framework was conducted. A purposeful sample of 19 graduate entry Master of Nursing Science students participating in a two-week interprofessional educational placement completed a reflective journal relating to an interprofessional placement in ambulatory care. The analysis of the journals found that all students were able to reflect on their interprofessional clinical experience, but the ability to reflect varied between students. Despite the challenges that some nursing students experienced in achieving deep levels of reflection, the study demonstrated the usefulness of incorporating reflective journals into nursing curriculums and as part of interprofessional practicums.     

瓜蒌皮与前列地尔预处理对心肌缺血再灌注的影响

探讨瓜蒌皮和前列地尔预处理对心肌缺血再灌注的作用机制.通过建立SD大鼠心肌缺血再灌注的模型,采用Tunel法检测组织样本细胞凋亡和免疫组化法检测bax,bcl-2,caspase-3的蛋白表达情况进行研究.结果显示,瓜蒌皮和前列地尔半剂量联合组的凋亡细胞数、Bax和caspase-3的蛋白表达量较其他各实验组均明显降低,Bcl-2的表达量升高,且有统计学意义(P＜0.05);瓜蒌皮单用药组也表现为凋亡细胞数、Bax和caspase-3的表达量降低,Bcl-2的表达量升高,但程度不如两组联合用药组.实验可以证明细胞凋亡发生在心肌缺血/再灌注损伤中,瓜蒌皮可对心肌缺血/再灌注起保护作用,并且与前列地尔联合后更有利于对心肌细胞的保护作用.     

TEACHING INDIVIDUALS TO SIGNAL FOR ASSISTANCE IN A TIMELY MANNER

The study describes the adaptive‐switch performances of eight adults with severe multiple impairments. Each was given a series of progressively more difficult discrimination tasks that, if solved, would require the participant to close the switch to activate a device that was not operating or to stay away from the switch if the device was operating. Then in a 2‐choice format, a preference test was conducted by providing two devices simultaneously that could be activated or deactivated by closure or release of the switch. Finally, a preferred device was activated and then surreptitiously deactivated. Switch closures in this contingency activated a speech‐generating device that played the message, ‘Help me’. All eight participants learned to control the devices by using their adaptive switch, but only four participants learned to make a request for help. Reasons for the different performances across learners and nonlearners are discussed. Copyright © 2012 John Wiley & Sons, Ltd.     

False external feedback modulates posterror slowing and the f-P300: implications for theories of posterror adjustment

People tend to slow down after mistakes. This posterror slowing (PES) has commonly been explained by a change to a more conservative response threshold to avoid future errors. Alternatively, the attention-orienting account posits that all infrequent, surprising events (including errors) elicit an orienting response followed by a time-consuming process of task reorientation, explaining PES without increased response caution. In the present study, we employed both behavioral and electrophysiological measures to compare the predictions of these accounts using a flanker paradigm in which accurate or false external response feedback was provided. Participants demonstrated typical posterror adjustments, responding more slowly and accurately in posterror than in postcorrect trials. This finding provides initial evidence suggesting that posterror adjustments are motivated by the avoidance of subsequent mistakes. Most importantly, PES and an event-related potential relating to the attentional processing of feedback, the feedback-related P300 (f-P300), were modulated by feedback type. More specifically, the f-P300 was larger after false than after accurate feedback, suggesting that participants oriented their attention toward (i.e., were surprised by) inaccurate feedback signals. Interestingly, false feedback differentially modulated reaction times: Participants were slower after correct responses when feedback falsely informed of an error rather than confirmed the correct response. In contrast, faster responses were made after errors when feedback falsely indicated correct rather than incorrect performance. When these patterns of results are regarded together, they are best explained by theories of cognitive control in which posterror adjustments in choice reaction time tasks are assumed to reflect control processes leading to more conservative performance after error signals.     

Trust and mistrust in organizations: An exploration using an organizational justice framework

This article commences with an overview of trust and mistrust, focusing on the debate about whether these are two ends of a continuum or distinct but interrelated concepts. Building on this review, the relationship between employees' perceptions of organizational justice and their self-categorized feelings of trust and mistrust is considered. It is suggested that organizational justice offers a useful means through which to explain and understand employees' feelings of trust and mistrust. Using case study data drawn from a UK public sector organization, the relationship between employees' feelings of trust and mistrust is explored within a change context. The data suggest that, whereas some employees perceive trust and mistrust as two ends of a continuum, others see them as distinct concepts. These findings are conceptualized as a trust?-?mistrust?-?absence triangle. Drawing on organizational justice as an explanatory theory, reasons for these findings are offered. The article concludes with a discussion regarding the coexistence of trust and mistrust and the explanatory value of organizational justice theory in understanding this.