Rat data which suggest alcoholic beverages should be swallowed during chemical aversion therapy,not just tasted

There were four pretraining procedures: A, in which rats drank sugar water prior to lithium sickness: P. in which sugar water was passed over the tongue prior to lithium sickness: Li, in which no taste experience preceded lithium sickness: NPT. in which the rats were exposed neither to the sugar water nor to lithium sickness. Lithium was then used to produce aversions to some other solution by dividing each of the pretraining groups into four subgroups. The solutions were novel NaCl, novel vinegar, novel alcohol, or familiar alcohol. Regardless of which solution was made aversive. the A pretraining procedure produced the strongest aversions and the Li procedure produced the weakest aversions. In the final phase, the preference for sugar water was tested. The A procedure produced far stronger aversions than the P procedure.     

The effects of clozapine on delayed spatial alternation deficits in rats with hippocampal damage

Clozapine is an atypical antipsychotic drug that has been shown to improve spatial memory in some animal models; however its efficacy in reversing spatial memory impairment in rats with hippocampal lesions is unknown. To address this issue, we tested the effects of clozapine on delayed spatial alternation deficits in rats with hippocampal damage in three separate experiments. In each experiment, adult male rats received sham surgery or direct stereotaxic infusions of the excitotoxin, NMDA, into the hippocampus. In the first study, seven days after surgery, the sham control animals received daily saline injections while the lesioned animals were split into two groups that received daily saline or clozapine (2.0 mg/kg, sc) injections. During the fifth week of injections, all animals were tested in a food-motivated delayed spatial alternation task. Saline-treated rats with excitotoxic hippocampal damage displayed significant deficits in delayed spatial alternation. Daily clozapine injections completely reversed this deficit. In a second experiment, it was found that clozapine treatment limited to the testing days only did not improve alternation performance in lesioned rats. Finally, in a third experiment, chronic clozapine treatment did not improve alternation performance in lesioned rats that were pre-trained in the alternation task prior to surgery. These results suggest that chronic, but not acute, clozapine treatment enables rats with hippocampal damage to develop new spatial learning, but can not rescue old spatial learning established prior to damage. These results may have implications for the treatment of cognitive deficits caused by hippocampal dysfunction in disorders such as schizophrenia, Alzheimer's disease, and others.     

Investigating the relationship between product involvement and consumer decision‐making styles

• Recently, a number of studies have investigated consumer decision‐making styles (CDMS) and their importance to consumer behaviour research. However, research designs suggested to date are mainly replications of a study by Sproles and Kendall ( 1986 ) proposing eight mental characteristics, the so‐called Consumer Styles Inventory (CSI). The CSI has been applied across cultures, but without critically examining its validity and reliability. A major concern is the postulated product independence of CSI. The aim of this study is to further develop this approach, to apply it to different product categories and to investigate the relationship between product involvement and CDMS. In doing so, we conducted a survey in Great Britain and Germany, and analysed the data using exploratory and confirmatory factor analysis. Not only did we demonstrate that there is a relationship between products and CDMS, but also that CDMS are governed by consumers' perceived product involvement. Important implications for marketing practice can be derived.

Copyright © 2006 John Wiley & Sons, Ltd.     

Identical elements model of arithmetic memory: Extension to addition and subtraction

The identical elements (IE) model of arithmetic fact representation (Rickard, 2005; Rickard & Bourne, 1996) was developed and tested with multiplication and division. In Experiment 1, we demonstrated that the model also applies to addition and subtraction by examining transfer of response time (RT) savings between prime and probe problems tested in the same block of trials. As is predicted by the IE model, there were equivalent probe RT savings for addition with identical repetition (prime 6 + 9 --> probe 6 + 9) or an order change (9 + 6 --> 6 + 9), but much greater savings for subtraction with identical repetition (15 - 6 --> 15 - 6) than with an order change (15 - 9 --> 15 - 6), and no savings with an operation change (15 - 9 --> 6 + 9 or 6 + 9 --> 4 15 - 6). In Experiment 2, we examined transfer in simple multiplication and division and demonstrated symmetrical transfer between operations. Cross-operation RT savings were eliminated, however, when the RT analysis included only trials on which both the prime and the probe problems were reportedly solved by direct retrieval. An IE model extended to accommodate savings associated with procedural strategies provides a coherent account of facilitative transfer effects in simple arithmetic.     

Expect the unexpected: ability, attitude, and responsiveness to hypnosis

Participants' expectancies and hypnotic performance throughout the course of a standardized, individually administered hypnotic protocol were analyzed with a structural equation model that integrated underlying ability, expectancy, and hypnotic response. The model examined expectancies and ability as simultaneous predictors of hypnotic responses as well as hypnotic responses as an influence on subsequent expectancies. Results of the proposed model, which fit very well, supported each of the 4 major hypothesized effects: Expectancies showed significant stability across the course of the hypnosis protocol; expectancies influenced subsequent hypnotic responses, controlling for latent ability; hypnotic responses, in turn, affected subsequent expectancies; and a latent trait underlay hypnotic responses, controlling for expectancies. Although expectancies had a significant effect on hypnotic responsiveness, there was an abundance of variance in hypnotic performance unexplained by the direct or indirect influence of expectation and compatible with the presence of an underlying cognitive ability.     

Parietal lobe contributions to episodic memory retrieval

Although the parietal lobe is not traditionally thought to support declarative memory, recent event-related fMRI studies of episodic retrieval have consistently revealed a range of memory-related influences on activation in lateral posterior parietal cortex (PPC) and precuneus extending into posterior cingulate and retrosplenial cortex. This article surveys the fMRI literature on PPC activation during remembering, a literature that complements earlier electroencephalography data. We consider these recent memory-related fMRI responses within the context of classical ideas about parietal function that emphasize space-based attention and motor intention. We conclude by proposing three hypotheses concerning how parietal cortex might contribute to memory.