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141.
Huismann DJ Sheldon JP Yashar BM Amburgey K Dowling JJ Petty EM 《Journal of genetic counseling》2012,21(5):713-725
Emerging adulthood is an important period in the development of one's identity and autonomy. The ways in which identity and autonomy are viewed by emerging adults and how they impact quality of life (QoL) in individuals with early-onset neuromuscular conditions is not yet known. This study focused on understanding and exploring relationships between self-perceptions of emerging adulthood, autonomy, and QoL. Five previously validated measures were incorporated into an online survey and distributed to young adults with early-onset neuromuscular conditions and unaffected controls. Topics explored included individuals' views regarding their overall QoL, disease-specific QoL, components of emerging adulthood, and autonomy. We found that a sense of higher disease impact was associated with a lower Overall General QoL. Additionally, perceptions of key autonomy factors "negativity" and "instability" were uniquely associated with Overall General QoL in the case group as compared to controls, whereas "attitudinal autonomy" (attaining the ability to plan and follow through with goals) was important to this age group regardless of health status. The specific factors of emerging adulthood and autonomy that were significantly correlated with Overall General QoL can be used for developing targeted counseling and interventions to improve QoL for individuals and their families. 相似文献
142.
The field of genetic counseling faces a broad challenge: many potential clients may not be aware of the value and benefit
of genetic counseling services, and therefore may not utilize those services. Navigenics is a personal genomic testing company
that provides telephonic genetic counseling services for multifactorial diseases and pharmacogenetics. When first offered
in 2008, utilization of the Navigenics genetic counseling service was less than expected. To explore the basis for under-utilization
and potential mechanisms for increasing uptake, Navigenics initiated a quality improvement study, in which three different
methods of engaging clients in the uptake of genetic counseling services were assessed over the course of 1 year. Outcomes
showed significant differences in uptake rates between methodologies (7.5%, 24.6%, and 60.1%), yielding an 8-fold increase
in service utilization when post-test telephonic outreach to all clients was performed. Further, utilization spanned all risk
levels based on client results, evidence that not only clients with high-risk results were motivated to engage in the genetic
counseling service. This research indicates that implementing strategies to educate clients about genetic counseling can positively
impact client engagement and utilization of available services. 相似文献
143.
Delaney M Leroi I Simpson J Overton PG 《Journal of clinical psychology in medical settings》2012,19(3):338-346
Parkinson's disease (PD) is a progressive neurodegenerative disease primarily characterised by motor symptoms. However, another feature of PD which is receiving increasing attention is the phenomenon of impulse control disorders (ICDs), such as pathological gambling. To date, research into ICDs in PD has centred on a biomedical model of cause, related to the effects of dopamine replacement therapy. However, there are several areas of discrepancy in the current biomedical account of ICDs in PD. In addition, we argue that social and psychological factors also need to be considered to achieve a more complete understanding of the phenomenon. We present a novel conceptual model which combines biomedical and psychosocial factors in the genesis of ICDs in PD and use the model to identify a number of potential treatment intervention points and to highlight important outstanding questions concerning the inter-relationship between psychosocial and biomedical factors in the genesis of ICDs in PD. 相似文献
144.
S Kuntz B Poeck MB Sokolowski R Strauss 《Learning & memory (Cold Spring Harbor, N.Y.)》2012,19(8):337-340
Orientation and navigation in a complex environment requires path planning and recall to exert goal-driven behavior. Walking Drosophila flies possess a visual orientation memory for attractive targets which is localized in the central complex of the adult brain. Here we show that this type of working memory requires the cGMP-dependent protein kinase encoded by the foraging gene in just one type of ellipsoid-body ring neurons. Moreover, genetic and epistatic interaction studies provide evidence that Foraging functions upstream of the Ignorant Ribosomal-S6 Kinase 2, thus revealing a novel neuronal signaling pathway necessary for this type of memory in Drosophila. 相似文献
145.
Heather O'Mahen Gina Fedock Erin Henshaw Joseph A. Himle Jane Forman Heather A. Flynn 《Cognitive and behavioral practice》2012,19(2):359-371
The evidence for the efficacy of CBT for depression during the perinatal period is mixed. This was a qualitative study that aimed to understand the perinatal-specific needs of depressed women in an effort to inform treatment modifications that may increase the relevance and acceptability of CBT during this period. Stratified purposeful sampling resulted in 23 participants selected by pregnancy, socioeconomic, and depression status. Participants completed semistructured interviews exploring their experiences of pregnancy and the postpartum period and its relationship to mood, and perspectives on ideal treatment content. Thematic analysis revealed a number of perinatal-specific themes that were relevant to CBT in three key domains: self, motherhood, and interpersonal. Mothers particularly struggled with: internalization of “motherhood myths,” self-sacrifice, and managing social support during this period. Shifts in women's themes across the perinatal period, and between racial and socioeconomic groups are discussed as are implications for modification of CBT to improve relevance for perinatal depression. 相似文献
146.
Hartley AA Maquestiaux F Brooks RD Festini SB Frazier K 《Cognitive, affective & behavioral neuroscience》2012,12(3):543-556
There is a response selection bottleneck that is responsible for dual-task interference. How the response selection bottleneck operates was addressed in three dual-task experiments. The overlap between two tasks (as indexed by the stimulus onset asynchrony [SOA]) was systematically manipulated, and both reaction time and electrodermal activity were measured. In addition, each experiment also manipulated some aspect of the difficulty of either task. Both increasing task overlap by reducing SOA and increasing the difficulty of either task lengthened reaction times. Electrodermal response was strongly affected by task difficulty but was only weakly affected by SOA, and in a different manner from reaction time. A fourth experiment found that the subjectively perceived difficulty of a dual-task trial was affected both by task difficulty and by SOA, but in different ways than electrodermal activity. Overall, the results were not consistent with a response selection bottleneck that involves processes of voluntary, executive attention. Instead, the results converge with findings from neural network modeling to suggest that the delay of one task while another is being processed reflects the operation of a routing mechanism that can process only one stream of information for action at a time and of a passive, structural store that temporarily holds information for the delayed task. The results suggest that conventional blocked or event-related neuroimaging designs may be inadequate to identify the mechanism of operation of the response selection bottleneck. 相似文献
147.
Many journals in the physical sciences require authors to submit assurances of compliance with human subjects and other research ethics standards. These requirements do not cover all disciplines equally, however. In this paper we report on the findings of a survey of perceptions of ethical and managerial problems from journal editors in political science and related disciplines. Our results show that few journals in political science require assurance statements common to journals for other scientific disciplines. We offer some reasons for this as well as some recommendations for implementing ethical assurance safeguards for political science. 相似文献
148.
149.
We investigated teacher versus student seat selection in the context of group and individual seating arrangements. Disruptive behavior during group seating occurred at twice the rate when students chose their seats than when the teacher chose. During individual seating, disruptive behavior occurred more than three times as often when the students chose their seats. The results are discussed in relation to choice and the matching law. 相似文献
150.
Bicard DF Lott V Mills J Bicard S Baylot-Casey L 《Journal of applied behavior analysis》2012,45(1):205-210
This study examined the effects of text messaging class arrival to an academic counselor on the attendance and punctuality of 4 college student athletes. Each participant had a history of class tardiness and was considered to be at risk for academic failure. Class attendance and punctuality improved for all participants. 相似文献