Pramipexole: augmentation in the treatment of depressive symptoms

We describe a retrospective case series of three patients, two with bipolar depression and one with unipolar depression. Pramipexole is a Food and Drug Administration-approved antiparkinsonian agent, which, when used to augment antidepressants, would be considered an off-label use and should be discussed with the patient. These patients had robust responses to pramipexole augmentation of their treatment regimen. All three patients had been taking an atypical antipsychotic. The depressive symptoms were evaluated using the Hamilton Rating Scale for Depression.     

Optimism in close relationships: How seeing things in a positive light makes them so

Does expecting positive outcomes--especially in important life domains such as relationships--make these positive outcomes more likely? In a longitudinal study of dating couples, the authors tested whether optimists (who have a cognitive disposition to expect positive outcomes) and their romantic partners are more satisfied in their relationships, and if so, whether this is due to optimists perceiving greater support from their partners. In cross-sectional analyses, both optimists and their partners indicated greater relationship satisfaction, an effect that was mediated by optimists' greater perceived support. When the couples engaged in a conflict conversation, optimists and their partners saw each other as engaging more constructively during the conflict, which in turn led both partners to feel that the conflict was better resolved 1 week later. In a 1-year follow-up, men's optimism predicted relationship status. Effects of optimism were mediated by the optimists' perceived support, which appears to promote a variety of beneficial processes in romantic relationships.     

Development of personality in early and middle adulthood: set like plaster or persistent change?

Different theories make different predictions about how mean levels of personality traits change in adulthood. The biological view of the Five-factor theory proposes the plaster hypothesis: All personality traits stop changing by age 30. In contrast, contextualist perspectives propose that changes should be more varied and should persist throughout adulthood. This study compared these perspectives in a large (N = 132,515) sample of adults aged 21-60 who completed a Big Five personality measure on the Internet. Conscientiousness and Agreeableness increased throughout early and middle adulthood at varying rates; Neuroticism declined among women but did not change among men. The variety in patterns of change suggests that the Big Five traits are complex phenomena subject to a variety of developmental influences.     

A Monte Carlo investigation of conjoint analysis index-of-fit: Goodness of fit,significance and power

Researchers in the field of conjoint analysis know the index-of-fit values worsen as the judgmental error of evaluation increases. This simulation study provides guidelines on the goodness of fit based on distribution of index-of-fit for different conjoint analysis designs. The study design included the following factors: number of profiles, number of attributes, algorithm used and judgmental model used. Critical values are provided for deciding the statistical significance of conjoint analysis results. Using these cumulative distributions, the power of the test used to reject the null hypothesis of random ranking is calculated. The test is found to be quite powerful except for the case of very small residual degrees of freedom.The authors thank the editor, the three reviewers and Ellen Foxman for helpful comments on the paper. Sanjay Mishra was a doctoral student at Washington State University at the time this research was completed. He is currently in the Department of Marketing at the University of Kansas.     

Building to discover: a common coding model

I present a case study of scientific discovery, where building two functional and behavioral approximations of neurons, one physical and the other computational, led to conceptual and implementation breakthroughs in a neural engineering laboratory. Such building of external systems that mimic target phenomena, and the use of these external systems to generate novel concepts and control structures, is a standard strategy in the new engineering sciences. I develop a model of the cognitive mechanism that connects such built external systems with internal models, and I examine how new discoveries, and consensus on discoveries, could arise from this external-internal coupling and the building process. The model is based on the emerging framework of common coding, which proposes a shared representation in the brain between the execution, perception, and imagination of movement.     

The Heart and the Head: On Choosing Experiences Intuitively and Possessions Deliberatively

An enduring question in the field of judgment and decision making is when people are likely to choose on the basis of intuition and when they are likely to pursue a more deliberative decision strategy. Here, we attempt to shed light on that question by examining whether people tend to weight intuition more heavily when making experiential purchases, and to weight deliberation more heavily when making material purchases. Results from seven studies indicate that they do. In Study 1 (and a replication), participants expressed an explicit preference for choosing experiential purchases intuitively and material purchases analytically. In Study 2 (and a replication), participants anticipated experiencing more regret after going against reason for material purchases and going against intuition for experiential purchases. Participants in Study 3 who were asked to think about an experiential purchase wanted to see the relevant information presented by alternative, which facilitates intuitive/holistic processing, more than did those who were asked to consider a material purchase. In two additional studies, participants who were induced to think intuitively chose experiential purchases more often (Study 4) and reported a higher willingness to pay for them (Study 5) compared with participants induced to think analytically. Copyright © 2016 John Wiley & Sons, Ltd.     

Pressure-induced structural transition in UGa2

High-pressure X-ray diffraction has been performed on UGa₂ up to 20?GPa using a diamond anvil cell. UGa₂ exhibits the AlB₂-type structure with space group P6/mmm at room temperature and atmospheric pressure. At about 16?GPa a reversible structural transformation to a tetragonal phase was observed. The bulk modulus of the AlB₂-type phase has been determined to be ～100?GPa, which is comparable to rare earth digallides like TmGa₂ and HoGa₂.     

Gandhi’s Synthesis of Liberal and Communitarian Values: Its Basis and Insights

Journal of Indian Council of Philosophical Research - It is well known that notions of individual sovereignty, universal rights, and the duty to follow one’s own conscience are central to the...     

Comparison, Grouping, and Preference

How does the attractiveness of a particular option depend on comparisons drawn between it and other alternatives? We observe that in many cases, comparisons hurt: When the options being compared have both meaningful advantages and meaningful disadvantages, comparison between options makes each option less attractive. The effects of comparison are crucial in choice problems involving grouped options, because the way in which options are grouped influences which comparisons are likely to be made. In particular, we propose that grouping focuses comparison, making within-group comparisons more likely than between-group comparisons. Consistent with this prediction, experimental results showed that grouping hurts: An option is more likely to be chosen when alone than when part of a group.