GSK-3β activity in the hippocampus is required for memory retrieval

Several molecules were recently found to be important for the memory retrieval process in the hippocampus; however, the mechanisms underlying the memory retrieval remain poorly understood. GSK-3β has been implicated in the control of synaptic plasticity and memory formation. Here, we investigated the relationship between hippocampal GSK-3β activity and memory retrieval using behavioral and Western blotting methods. We found that GSK-3β was activated in the hippocampus after a retention session in the passive avoidance task. An intrahippocampal injection of the GSK-3β inhibitor, SB 216763, before the retention session blocked memory retrieval (but not reconsolidation) without affecting locomotor activity. These results suggest that GSK-3β activation would be essential for memory retrieval in the hippocampus.     

A Compulsive Buying Case: A Qualitative Analysis by the Grounded Theory Method

This study analyzed a case of compulsive buying based on the grounded theory method. The client was a 24 year-old female Korean student who showed compulsive buying and excessive credit card use. The family therapy was performed between March 2001 and May 2004 in Korea. This study used the software “Atlas.ti,” producing 121 open codings and seven axis categories which included the following: (1) communication issues with friends or family members, (2) sibling relationships, (3) mother’s parenting, (4) interparental relationships, (5) mother’s communication style, (6) stress, and (7) compulsive buying and credit card use. This study presented the graphical network among these categories in order to show the effectiveness of family therapy.This work was supported by the Soongsil University Fund.     

Marriage and Family Therapy Students’ Change in Multicultural Counseling Competencies after a Diversity Course

Attention to diversity is required in Commission on Accreditation for Marriage and Family Therapy Education-accredited programs, yet not much research exists regarding the effectiveness of graduate training on therapists’ multicultural counseling competencies. In this study, 12 students enrolled in a masters-level diversity class were given pre- and post-tests of their multicultural counseling competencies. Results showed that students significantly increased their multicultural awareness, knowledge, and skills after completing the diversity class. The discussion includes implications for educators who seek to improve students’ multicultural counseling competencies.     

A PROBLEM-SOLVING APPROACH TO SOCIAL SKILLS TRAINING IN EMPLOYMENT SETTINGS WITH MENTALLY RETARDED YOUTH

The present study examined two approaches to teaching social behaviors to 3 developmentally disabled youths in work contexts. In one approach, a problem-solving procedure was learned and transferred to different materials. Conversational probes monitored interactions between disabled employees and their co-workers and customers. A multiple baseline design demonstrated that the training produced generalization and maintenance of the targeted social behaviors to the work settings. A second approach based on a role-playing intervention produced no substantial generalization in the work setting. A social validation questionnaire administered to co-workers supported the efficacy of the problem-solving training procedure. The efficacy of social problem-solving training was discussed in terms of sufficient exemplars, common stimuli, and self-mediations.     

Memory for two types of spatial location: effects of instructions, age, and format

Three experiments, with old persons (59-80 years) and college students (17-30 years) in Experiments 1 and 2 and with college students (17-24 years) in Experiment 3, investigated the differences between two types of spatial location memory: memory for the location of individual items in an array and memory for occupied, as opposed to unoccupied, locations in an array. Young persons performed better than old persons on both measures of location memory. However, an effect of instructions (intentional vs. incidental for spatial location) was consistently obtained for memory for occupied, as opposed to unoccupied, locations, whereas no effect of instructions was obtained for memory for individual item locations. In addition, item location memory was superior for objects as opposed to matched words (Experiment 2), whereas occupied location memory was not affected by presentation format (Experiments 2 and 3). These differences indicate that spatial memory is a complex process whose properties are affected by variations in stimulus characteristics and task demands. It was concluded that the distinction of Hasher and Zacks (1979) between automatic and effortful processes is not adequate for understanding spatial memory. A recognition of the complex nature of spatial processing suggests a resolution of discrepancies in the literature based upon differences in stimulus characteristics, task demands, and the effectiveness of task-appropriate mnemonic strategies.     

Perceptual organization of acoustic stimuli by budgerigars (Melopsittacus undulatus): I. Pure tones

A new combination of operant conditioning and psychophysical scaling procedures was used to study auditory perception in a small bird. In a same-different discrimination task, budgerigars learned to discriminate among pure tones that varied along one or more acoustic dimensions. Response latencies were used to generate a matrix of interstimulus similarities. Multidimensional scaling procedures were used to arrange these acoustic stimuli in a multidimensional space that supposedly reflects the bird's perceptual organization. For tones that varied in intensity, duration, and frequency simultaneously, budgerigars were much more sensitive to frequency changes. From a set of tones that varied only in intensity, it was possible to calculate the growth of loudness with intensity for the budgerigar. For tones that varied only in frequency, budgerigars showed evidence of an "acoustic fovea" for frequency change in the spectral region of 2-4 kHz. Budgerigars and humans also differed in their perceptual grouping of tone sequences that rise, fall, or remain constant in pitch. Surprisingly, budgerigars were much less responsive to pitch contour than were humans.