Knockdown of Nurr1 in the rat hippocampus: implications to spatial discrimination learning and memory

Nurr1 expression is up-regulated in the brain following associative learning experiences, but its relevance to cognitive processes remains unclear. In these studies, rats initially received bilateral hippocampal infusions of control or antisense oligodeoxynucleotides (ODNs) 1 h prior to training in a holeboard spatial discrimination task. Such pre-training infusions of nurr1 antisense ODNs caused a moderate effect in learning the task and also impaired LTM tested 7 d later. In a second experiment, ODN infusions were given immediately after the animals had received two sessions of training, during which all animals showed normal learning. Although antisense treated rats were significantly impaired during the post-infusion stages of acquisition of the task, no group differences were observed during the LTM test given 7 d later. These animals were subjected 3 d later to reversal training in the same maze in the absence of any additional treatments. Remarkably, rats previously treated with antisense ODNs displayed perseveration: The animals were fixated with the previously learned pattern of baited holes, causing them to be significantly impaired in the extinction of acquired spatial preferences and future learning. We postulate that Nurr1 function in the hippocampus is important for normal cognitive processes.     

A matter of time: novel nouns mark object categories when delays are imposed

In previous work, preschool-aged children have revealed a specific expectation that novel count nouns (but not adjectives) will refer to object categories (but not to object properties or to thematic relations). However, in these tasks, children have been permitted to extend a novel word immediately after it has been introduced. The current experiments test the hypothesis that the noun-category bias is sufficiently robust to hold up even when a delay is imposed between a naming episode and the child’s opportunity for extension. To capture this phenomenon experimentally, we imposed delays of 30 s (Experiment 1) and 1 h (Experiment 2). Across both delay conditions, children in a ‘novel noun’ condition revealed a strong inclination to consistently choose other members of the same object category as the (previously named) target. Children in either a ‘novel adjective’ or ‘no word’ condition revealed no taxonomic inclination. These results establish the power of the noun-category bias in situations that more closely approximate some of the very real challenges that children face in mapping and extending novel words.     

Sex role egalitarianism and marital violence

This study explores the link between sex role egalitarianism and marital violence using a sample of men enrolled in either substance abuse treatment programs (N=71) or in anger management programs (N=44). It was found that men in both treatment programs had very similar levels of egalitarianism and violence in their relationships. Using the combined sample, it was found that having attitudes approving of marital violence and using “severe” violence accounted for a significant portion of the variance in sex role egalitarianism, whereas use of “minor” violence did not account for significant variance in egalitarianism. These results suggest that sex role egalitarianism may be a meaningful indicator for spouse abuse.     

The counseling psychologist in business and industry: Ethical concerns

Ethical concerns of counseling psychologists practicing in business and industry are explored in the context of values conflicts, operational issues, and strategies for resolution. An emphasis is placed on strategies evolving from preparation and self-knowledge.     

Inferences of mental illness from noninvolvement

These studies continue the exploration of variables related to a person's use of the mental illness categorization. The central concern in the present studies was the effect of perceived variation in a target person's level of involvement in a social situation. While a low level of involvement, as portrayed in videotaped scenarios, prompts attribution of mental illness, other features of implicit personality theories also relate to greater or lesser attribution of mental illness. Those participants who gave evidence of having attributed lower levels of involvement, regardless of filmed information, also attributed higher levels of mental illness. Social workers, compared to general population participants, attributed higher levels of mental illness at all levels of target involvement. We discuss the implications of these findings for dissemination and assignment of the mentally ill role.     

Sex differences: A study of the ear of the beholder

Male and female adult Ss, while performing an unrelated task, heard a single infant awakening. The infant was labeled a girl or a boy. The dependent variable was how quickly Ss responded to the crying infant. Females responded more quickly to the girl than to the boy. Males responded equally slowly to boy and girl. A questionnaire on sex differences in fragility showed that females and males tend to disagree with the proposition that girls are more fragile than boys. Thus, the females' faster response to a crying girl cannot be accounted for by a belief in sex-differential fragility. Correlations between fragility beliefs and response times to an infant indicate that sex-differential belief-behavior relationships are not the same for males and females.     

Optional shift behavior as a function of age and dimensional dominance

An optional reversal-nonreversal shift task for which the relevant color or form cues were either dominant or nondominant was presented to 320 Ss, 6 through 20 years of age. Dominance, as defined in terms of relative cue similarity, was related to initial learning and shift behavior for kindergarten and third-grade Ss; but not for sixth-grade and college Ss. The speed of initial learning and percentage of reversal shifts was related to age when the nondominant dimension was relevant. There were no developmental differences when the dominant dimension was relevant.