The perception of tempo in music

Tempo is one factor that is frequently associated with the expressive nature of a piece of music. Composers often indicate the tempo of a piece of music through the use of numerical markings (beats min(-1)) and subjective terms (adagio, allegro). Three studies were conducted to assess whether listeners were able to make consistent judgments about tempo that varied from piece to piece. Listeners heard short extracts of Scottish music played at a range of tempi and were asked to make a two-alternative forced choice of "too fast" or "too slow" for each extract. The responses for each study were plotted as proportion of too fast responses as a function of tempo for each piece, and cumulative normal curves were fitted to each data set. The point where these curves cross 0.5 is the tempo at which the music sounds right to the listeners, referred to as the optimal tempo. The results from each study show that listeners are capable of making consistent tempo judgments and that the optimal tempo varies across extracts. The results also revealed that rhythm plays a role, but not the only role in making temporal judgments.     

The liebowitz social anxiety scale as a self-report instrument: a preliminary psychometric analysis

The Liebowitz social anxiety scale (LSAS) is a commonly used clinician-administered instrument. The present study reports on the properties of a self-report version of the LSAS (LSAS-SR). About 175 participants diagnosed with social phobia participated in the study. The LSAS-SR showed overall good psychometric properties as indicated by the results of test-retest reliability, internal consistency, and convergent and discriminant validity. Furthermore, the scale was sensitive to treatment change. The construct validity of the LSAS-SR, however, remains to be further explored. These findings support the utility of the LSAS-SR, which has the advantage of saving valuable clinician time compared to the clinician-administered version.     

Word learning is 'smart': evidence that conceptual information affects preschoolers' extension of novel words

We examined electrophysiological correlates of conscious change detection versus change blindness for equivalent displays. Observers had to detect any changes, across a visual interruption, between a pair of successive displays. Each display comprised grey circles on a background of alternate black and white stripes. Foreground changes arose when light-grey circles turned dark-grey and vice-versa. Physically stronger background changes arose when all black stripes turned white and vice-versa. Despite their physical strength, background changes were undetected unless attention was directed to them, whereas foreground changes were invariably seen. Event-related potentials revealed that the P300 component was suppressed for unseen background changes, as compared with the same changes when seen. This effect arose first over frontal sites, and then spread to parietal sites. These results extend recent fMRI findings that fronto-parietal activation is associated with conscious visual change detection, to reveal the timing of these neural correlates.     

Behavioral activation and the prevention of suicidal behaviors in patients with borderline personality disorder

Clinical approaches in treating and preventing suicidal behaviors in patients with borderline personality disorder (BPD) have received limited attention. To stimulate further work in this area, we present a behavioral activation treatment for depression (BATD; Lejuez, Hopko, & Hopko, 2002) that has shown promising results in treating clinically depressed patients and a theoretical conceptualization for why BATD may prove particularly useful in reducing the frequency of suicide-related behaviors and other symptoms characteristic of patients with BPD. We also present theoretical consistencies between BATD and the well-established intervention of dialectical behavior therapy (DBT; Linehan, 1993), which may allow for their practical integration, and conclude with a case study that illustrates the assimilation of these strategies in the treatment of a patient with BPD.     

Hippocampal gene expression profiling in spatial discrimination learning

Learning and long-term memory are thought to involve temporally defined changes in gene expression that lead to the strengthening of synaptic connections in selected brain regions. We used cDNA microarrays to study hippocampal gene expression in animals trained in a spatial discrimination-learning paradigm. Our analysis identified 19 genes that showed statistically significant changes in expression when comparing Nai;ve versus Trained animals. We confirmed the changes in expression for the genes encoding the nuclear protein prothymosin(alpha) and the delta-1 opioid receptor (DOR1) by Northern blotting or in situ hybridization. In additional studies, laser-capture microdissection (LCM) allowed us to obtain enriched neuronal populations from the dentate gyrus, CA1, and CA3 subregions of the hippocampus from Nai;ve, Pseudotrained, and spatially Trained animals. Real-time PCR examined the spatial learning specificity of hippocampal modulation of the genes encoding protein kinase B (PKB, also known as Akt), protein kinase C(delta) (PKC(delta)), cell adhesion kinase(beta) (CAK(beta), also known as Pyk2), and receptor protein tyrosine phosphatase(zeta/beta) (RPTP(zeta/beta)). These studies showed subregion specificity of spatial learning-induced changes in gene expression within the hippocampus, a feature that was particular to each gene studied. We suggest that statistically valid gene expression profiles generated with cDNA microarrays may provide important insights as to the cellular and molecular events subserving learning and memory processes in the brain.     

Judging the animacy of words: The influence of typicality and age of acquisition in a semantic decision task

The age at which members of a semantic category are learned (age of acquisition), the typicality they demonstrate within their corresponding category, and the semantic domain to which they belong (living, non-living) are known to influence the speed and accuracy of lexical/semantic processing. So far, only a few studies have looked at the origin of age of acquisition and its interdependence with typicality and semantic domain within the same experimental design. Twenty adult participants performed an animacy decision task in which nouns were classified according to their semantic domain as being living or non-living. Response times were influenced by the independent main effects of each parameter: typicality, age of acquisition, semantic domain, and frequency. However, there were no interactions. The results are discussed with respect to recent models concerning the origin of age of acquisition effects.