Differential indication of trimipramine - results of a controlled multiclinical study]

The antidepressants trimipramine and imipramine were compared within the framework of a multiclinical study performed under the conditions of a controlled clinical experiment. There has been found a time-different remission of affective und psychomotoric symptoms. The panthymoleptic action of trimipramine and other antidepressants is discussed with reference to these results. Trimipramine influences psychotic states, especially if in depression anxiety is combined with agitation, also in hypochondriac forms of depression.     

Age-of-acquisition effects in lexical and episodic memory tasks

This paper reports four experiments on the effects of word age of acquisition in verbal tasks. In all cases, multiple-regression analysis was used to assess the relative effects of age as opposed to other potentially relevant word attributes. Experiments 1 and 2 concerned lexical memory tasks. In Experiment 1, picture naming speeds were found to be mainly determined by picture codability and name age of acquisition. In Experiment 2, it was found that when subjects produced words in response to bigram cues, early acquired target words were more likely to be produced than later acquired words, even when frequency and other word attributes were taken into account. The remaining two experiments dealt with the episodic memory tasks of free recall and recognition. No age effects were found in these tasks. It was concluded that early age of acquisition facilitates retrieval from lexical memory but has no significant effect in episodic memory tasks.     

What is right with “deep” dyslexic patients?

Two aphasic adults with a specific acquired dyslexia were given tests requiring the processing of written words and sentences. Despite the general severity of the patients' deficits, some aspects of such processing appear to be relatively well preserved. The patients have particular difficulty reading aloud function words and abstract words; yet in word/nonword discrimination tests, both patients showed normal recognition of function words and one showed normal performance with abstract words. The patients do have a deficit in comprehension of visually presented words and sentences; yet their performance on comprehension tests was considerable and, moreover, showed meaningful relationships with their ability to read aloud.     

Fact and fantasy: the roles of accuracy and variability in confusing imaginations with perceptual experiences

In Experiment 1, pictures were presented to subjects two, five, or eight times, and subjects were asked to imagine each pciture two, five, or eight times. Subsequently, subjects estimated the number of times each picture had been presented. Their estimates of the frequency of these external events were influenced by imagination trials; this effect was greater for good imagers than for poor imagers. Experiment 2 involved a similar design in which subjects were asked either to imagine the same referent for a word or to imagine a different referent for a word on successive imagination trials. Consistency (same referent) did not increase the influence of imaginations on immediate judgments of external frequency. Thus, the results of Experiment 1 were attributed to the greater accuracy (as opposed to greater consistency) of good imagers' internal generations of the stimuli. Furthermore, variation (imagining different referents), like greater accuracy, increased the effects of imagination trials on immediate but not on delayed judgments of frequency. Possible mechanisms underlying these effects are discussed. In general, the two studies show that qualitative characteristics of completely covert generations influence their impact on estimates of the frequency of external events.     

Time errors and differential sensation weighting

Sixteen pairs of successive tones, with different amplitude combinations, were presented with 16 combinations of tone duration and interstimulus interval. A separate group of 12 subjects was assigned to each presentation condition and made comparative loudness judgments for each of the pairs. Perceived within-pair loudness differences were scaled by a Thurstonian method using the subjective width of the "equal" category as the unit. The scale differences were well described by weighted linear combinations of the sensation magnitudes of the tones in the pairs. The time error can be regarded as an effect of this differential weighting. For the longer interstimulus intervals, the weight of the second tone was the greater, causing the usual inverse relation between time error and stimulus intensity level. For the shorter interstimulus intervals, these effects were reversed. An analysis of the pattern of weights led to the development of two models, one of which is a generalization of Michels and Helson's time error model. The weights could be interpreted as reflecting the differential efficiency of the loudness information from the two compared stimuli.