Executive functions,impulsivity, and inhibitory control in adolescents: A structural equation model

Background. Adolescence represents a critical period for brain development, addressed by neurodevelopmental models to frontal, subcortical-limbic, and striatal activation, a pattern associated with rise of impulsivity and deficits in inhibitory control. The present study aimed at studying the association between self-report measures of impulsivity and inhibitory control with executive function in adolescents, employing structural equation modeling. Method. Tests were administered to 434 high school students. Acting without thinking was measured through the Barratt Impulsiveness Scale and the Dickman Impulsivity Inventory, reward sensitivity through the Behavioral Activation System, and sensation seeking through the Zuckerman–Kuhlman–Aluja Personali- ty Questionnaire. Inhibitory control was assessed through the Behavioral Inhibition System. The performance at the Wisconsin Card Sorting Task indicated executive function. Three models were specified using Sample Covariance Matrix, and the estimated parameters using Maximum Likelihood. Results. In the final model, impulsivity and inhibitory control predicted executive function, but sensation seeking did not. The fit of the model to data was excellent. Conclusions. The hypothesis that inhibitory control and impulsivity are predictors of executive function was supported. Our results appear informative of the validity of self-report measures to examine the relation between impulsivity traits rather than others to regulatory function of cognition and behavior.     

The Interplay Between Trust Among Peers and Interpersonal Characteristics in Homophobic Bullying Among Italian Adolescents

This study is based on exploring the trust between peers and the individual characteristics related to homophobic bullying in adolescence. Participants were 334 adolescents (141 boys and 193 girls) aged from 15 to 20 years. Participants completed the homophobic bullying scale, to investigate bullying actions towards sexual minorities, the personal attributes questionnaire, for personal characteristics, and the inventory of parent and peer attachment, to the trust between peers. The results demonstrated how female participants manifested a higher level of interpersonal traits and trust among peers than boys. Results showed how a lack of trust between peers predicts homophobic bullying. Nevertheless, we found that the lack of interpersonal characteristics represents a variable that likely mediates the relationship between lack of trust in peers and homophobic bullying. Theoretical and practical implications are discussed.     

Science and Political Imperatives: Orders of Precedence

An ideal view is sketched of the relationship between the facts established in science and the values of ethics and politics, and of the distinction between them. Some necessary qualifications are drawn, which do not essentially undermine the ideal. Then two cases of scientific work are considered in which considerations of value may in different ways be playing a more intimate role in the science than the ideal would suggest. These are Darwin’s theory of evolution and the current consensus on climate change. Are any general lessons to be drawn from these cases?     

Print Me an Organ? Ethical and Regulatory Issues Emerging from 3D Bioprinting in Medicine

Recent developments of three-dimensional printing of biomaterials (3D bioprinting) in medicine have been portrayed as demonstrating the potential to transform some medical treatments, including providing new responses to organ damage or organ failure. However, beyond the hype and before 3D bioprinted organs are ready to be transplanted into humans, several important ethical concerns and regulatory questions need to be addressed. This article starts by raising general ethical concerns associated with the use of bioprinting in medicine, then it focuses on more particular ethical issues related to experimental testing on humans, and the lack of current international regulatory directives to guide these experiments. Accordingly, this article (1) considers whether there is a limit as to what should be bioprinted in medicine; (2) examines key risks of significant harm associated with testing 3D bioprinting for humans; (3) investigates the clinical trial paradigm used to test 3D bioprinting; (4) analyses ethical questions of irreversibility, loss of treatment opportunity and replicability; (5) explores the current lack of a specific framework for the regulation and testing of 3D bioprinting treatments.     

Examining Psychosocial Pathways Underlying Gratitude Interventions: A Randomized Controlled Trial

Despite their unprecedented popularity, the psychological mechanisms through which gratitude journals operate are poorly understood. Also the use of gratitude journaling to enhance social relationships has been neglected in past research, despite the importance of healthy relationships for people’s happiness. This randomized controlled study examined the effect of (a) a traditional gratitude journal (fostering gratitude for daily life), and (b) an interpersonal gratitude journal (fostering gratitude for one’s existing social relationships), versus (c) an active control journal, on life satisfaction. Ninety-one participants were randomized to one of three conditions with 2-week and 1-month follow-ups. The traditional gratitude intervention (vs. control) showed improvements in friendship at immediate post-test and 1-month follow-up, and these effects were accounted for by changes in gratitude over time. Additionally, the traditional gratitude intervention (vs. control) predicted enhanced life satisfaction at follow-up, and this was serially mediated by 6 week changes in gratitude and perceived friendship quality. No such differences over time were observed between the interpersonal gratitude intervention and either the control intervention or the traditional gratitude intervention. Actively appreciating things in daily life appears to be effective in enhancing the quality of people’s social relationships, and producing sustained improvements in subjective wellbeing.     

Interspecies transmission of emotional information via chemosignals: from humans to dogs (<Emphasis Type="Italic">Canis lupus familiaris</Emphasis>)

We report a study examining interspecies emotion transfer via body odors (chemosignals). Do human body odors (chemosignals) produced under emotional conditions of happiness and fear provide information that is detectable by pet dogs (Labrador and Golden retrievers)? The odor samples were collected from the axilla of male donors not involved in the main experiment. The experimental setup involved the co-presence of the dog’s owner, a stranger and the odor dispenser in a space where the dogs could move freely. There were three odor conditions [fear, happiness, and control (no sweat)] to which the dogs were assigned randomly. The dependent variables were the relevant behaviors of the dogs (e.g., approaching, interacting and gazing) directed to the three targets (owner, stranger, sweat dispenser) aside from the dogs’ stress and heart rate indicators. The results indicated with high accuracy that the dogs manifested the predicted behaviors in the three conditions. There were fewer and shorter owner directed behaviors and more stranger directed behaviors when they were in the “happy odor condition” compared to the fear odor and control conditions. In the fear odor condition, they displayed more stressful behaviors. The heart rate data in the control and happy conditions were significantly lower than in the fear condition. Our findings suggest that interspecies emotional communication is facilitated by chemosignals.     

The Good Immigrant Worker: 2013 US Senate Bill 744, Color-Blind Nativism and the Struggle for Comprehensive Immigration Reform

We explore immigration politics in the contemporary USA through analysis of the political framing of 2013 US Senate Bill 744, especially among its supporters. SB 744 is a bipartisan comprehensive immigration reform proposal that called for the largest overhaul of the immigration system in more than 25 years; it was passed in June 2013 by the US Senate but blocked in the House. Through analysis of the 2012–2013 textual content of the official websites and blogs of six US immigration lobby organizations from across the political spectrum, we offer a typology of political framings of comprehensive immigration reform. Drawing on popular anti-immigrant rhetoric, organizations with an agenda of immigration restriction and deterrence battled against the bill. On the other side, supporters of the bill ranged from business coalitions to immigrant rights groups, an assortment of interests that was reflected in the variety of arguments advanced in favor of the bill. Despite the far more fragmented character of pro-SB 744 discourse in comparison to that advanced by the opposition, our investigation suggests the ongoing and contested formation of a strategic pro-SB 744 framing that centered on the “good immigrant worker,” a “race-blind” trope that melds US nationalist narratives of immigration with an ethos of neoliberalism that upholds individual merit and market value to create a notion of “deservingness” that affirms the worth of immigrants as diligent workers.     

Enhancing theory of mind in behavioural variant frontotemporal dementia with transcranial direct current stimulation

Behavioural variant frontotemporal dementia (bvFTD) is a form of frontotemporal degeneration characterized by early changes in personality, emotional blunting, and/or loss of empathy. Recent research has highlighted that these features may be at least partially explained by impairments in the theory of mind (ToM; i.e., the ability to understand and predict other people’s behaviour by attributing independent mental states to them). The aim of this randomized, double-blind, placebo-controlled study was to test the hypothesis that transcranial direct current stimulation (tDCS) over the medial frontal cortex (MFC) selectively enhances communicative intention processing, a specific ToM ability. Using a single-session online design, we administered a ToM task that measures the ability to represent other people’s private and communicative intentions during active or sham tDCS to 16 bvFTD patients. To assess the impact of dementia on performance on the ToM task, we included 16 age-matched healthy volunteers who were asked to perform the entire experimental ToM task. BvFTD is characterized by an impairment in the comprehension of both communicative and private intentions relative to a healthy control group and by a disproportional impairment in communicative intention compared with private intention processing. Significant and selective accuracy improvement in the comprehension of communicative intentions after active stimulation was observed in patients with bvFTD. This is the first study that analyses ToM ability in patients with bvFTD using tDCS stimulation. Our findings could potentially contribute to the development of an effective, noninvasive brain stimulation treatment of ToM impairments in patients with bvFTD.