Effectiveness and safety of epilepsy surgery: what is the evidence?

Evidence from a recent randomized controlled trial of surgical versus medical therapy of temporal lobe epilepsy proves that antero-mesial resection is safe and more effective than medical therapy. The number of patients needed to treat for one patient to become free of disabling seizures is two, which is superior to most interventions in neurology. A meta-analysis of non-randomized trials gives almost identical results; about two-thirds of patients become seizure-free, compared with only 8% with medical therapy. The results are remarkably similar among studies from different parts of the world. Quality of life improves early after epilepsy surgery, the improvements are both statistically and clinically significant, and they are sustained. Surgical morbidity with clinically important permanent sequelae is 2%. Epilepsy surgery remains underutilized in developed countries and it does not exist in all but a few developing countries. Current randomized trials are underway to explore the effect of early surgery versus optimum medical therapy on the prevention of disability in patients with mesial temporal lobe epilepsy, and to examine the effectiveness of novel interventions, such as minimally invasive surgery and brain stimulation.     

Sex, sexual orientation, and identification of positive and negative facial affect

Sex and sexual orientation related differences in processing of happy and sad facial emotions were examined using an experimental facial emotion recognition paradigm with a large sample (N = 240). Analysis of covariance (controlling for age and IQ) revealed that women (irrespective of sexual orientation) had faster reaction times than men for accurate identification of facial emotion and were more accurate in identifying male faces than female ones, whereas men performed the same regardless of the sex of the face. However, there were no overall sex differences in accuracy. These findings suggest a limited role for sex in the perception of facial affect.     

Maternal regulation of infant reactivity from 2 to 6 months

Previous research has investigated the effect of maternal soothing behaviors on reducing infant reactivity but not the differential effects of specific maternal behaviors on infant stress responses. The present study investigated maternal regulation of 2- and 6-month-olds' responses to an inoculation and found a significant decline with age in both the intensity and duration of infants' crying. Maternal affection and touching decreased from 2 to 6 months, whereas maternal vocalizing and distraction behaviors increased. At both ages, the combination of maternal holding/rocking and vocalizing was associated with decreases in all levels of infant reactivity. Neither strategy alone, however, was found to be effective. Feeding/ pacifying behaviors were effective only when initial distress was at a low or moderate level, which suggests that the effectiveness of maternal regulatory behaviors may depend on the intensity of infants' crying.     

Shyness: relationship to social phobia and other psychiatric disorders

The relationship between shyness, social phobia and other psychiatric disorders was examined. The prevalence of social phobia was significantly higher among shy persons (18%) compared with non-shy persons (3%). However, the majority of shy individuals (82%) were not socially phobic. A significant and positive correlation was found between the severity of shyness and the presence of social phobia, but the data suggest that social phobia is not merely severe shyness. Social phobia was also positively and moderately correlated with introversion and neuroticism. Thus, shy persons with social phobia were shyer, more introverted, and more neurotic than other shy people, but none of these factors was sufficient to distinguish shy persons with social phobia from those without social phobia. The proportion of the shy group with psychiatric diagnoses other than social phobia was significantly higher than among the non-shy group, indicating that various diagnostic categories are prominent among the shy. The results are discussed in terms of the overlap in shyness and social phobia and the relationship of shyness to other psychiatric diagnoses and personality dimensions.     

The construct validity of depressive personality disorder

This study examined the construct validity of depressive personality disorder (DPD: American Psychiatric Association, 1994). Adult psychiatric outpatients (N = 900) underwent comprehensive Axis I and II evaluations and provided data on 4,768 of their 1st-degree relatives. Despite modest overlap, DPD was not redundant with any Axis I or II disorder. Participants with DPD exhibited more Axis I and Axis II comorbidity, and greater psychosocial dysfunction, than participants without DPD. Relatives of participants with DPD had higher rates of mood disorders, alcohol abuse, and antisocial personality. Results are consistent with findings of several other similar investigations. The authors argue that DPD is a valid construct and should be conceptualized as a personality disorder as opposed to a mood disorder.     

Limits of the retrieval-inhibition construct: list segregation in directed forgetting

The authors hypothesized that retrieval inhibition in list method directed forgetting could be improved by presenting a task that maximized the segregation step of the retrieval-inhibition process. In Experiment 1, they presented lists of semantically related words in a list method directed-forgetting task to maximize retrieval inhibition. Contrary to predictions, this manipulation eliminated the directed-forgetting effect. The authors further investigated the results of Experiment 1 in Experiments 2 and 3 by manipulating recall instructions and by presenting lists that contained both a categorized and an unrelated list-half. They found directed-forgetting effects for semantically related word lists when participants were asked to recall only the TBR (to-be-remembered) items but not when participants were asked to recall both the TBF (to-be-forgotten) and TBR items. They also found that directed-forgetting effects were not produced when categorized items were presented in the 1st list.     

A dog's got personality: a cross-species comparative approach to personality judgments in dogs and humans

This research offers a blueprint for how a cross-species comparative approach can be realized empirically. In a single design, parallel procedures and instruments were used in 2 species, dogs (Canis familiaris) and humans (Homo sapiens), to test whether personality differences exist and can be judged in dogs as accurately as in humans. Personality judgments of humans and dogs were compared on 3 accuracy criteria: internal consistency, consensus, and correspondence. Results showed that, on all 3 criteria, judgments of dogs were as accurate as judgments of humans. These findings are consistent with the evolutionary continuity hypothesis and suggest an important conclusion not widely considered by either personality or animal researchers: Personality differences do exist and can be measured in animals other than humans.     

Social dominance and ethical ideology: the end justifies the means?

Although many social psychological researchers have tried to identify the antecedents of unethical or immoral behavior, investigators have little considered the content of ethical beliefs that associate with important personality variables such as authoritarianism (B. Altemeyer, 1981, 1996) and social dominance orientation (SDO; J. Sidanius, 1993). Previous studies suggest that authoritarianism is associated with the rejection of relativistic standards for moral actions and--to a lesser extent--the idealistic belief that moral actions should not harm others (J. W. McHoskey, 1996). In the present study, 160 New Zealand University students completed measures of SDO (J. Sidanius), Right Wing Authoritarianism (RWA, B. Altemeyer, 1981), and two subscales of ethical ideology: Relativism and Idealism (D. R. Forsyth, 1980). As expected, SDO showed a negative relationship with Idealism, a belief that actions should not harm others. But, contrary to expectations, SDO showed no consistent association with relativism, a belief that the moralities of actions are not comparable. On the basis of those findings, people with high SDO might be described as "ruthless" in their pursuit of desirable goals and are indifferent about whether the morality of different actions can be compared or even matter.     

Location, location, location: the misprediction of satisfaction in housing lotteries

People tend to overestimate the emotional consequences of future life events, exhibiting an impact bias. The authors replicated the impact bias in a real-life context in which undergraduates were randomly assigned to dormitories (or "houses"). Participants appeared to focus on the wrong factors when imagining their future happiness in the houses. They placed far greater weight on highly variable physical features than on less variable social features in predicting their future happiness in each house, despite accurately recognizing that social features were more important than physical features when asked explicitly about the determinants of happiness. In Experiment 2, we found that this discrepancy emerged in part because participants exhibited an isolation effect, focusing too much on factors that distinguished between houses and not enough on factors that varied only slightly, such as social features.