A placebo-controlled randomized trial of D-cycloserine augmentation of cue exposure therapy for smoking cessation

Recent studies underscore the importance of studying d-cycloserine (DCS) augmentation under conditions of adequate cue exposure treatment (CET) and protection from reconditioning experiences. In this randomized trial, we evaluated the efficacy of DCS for augmenting CET for smoking cessation under these conditions.

Sixty-two smokers attained at least 18 hours abstinence following 4 weeks of smoking cessation treatment and were randomly assigned to receive a single dose of DCS (n=30) or placebo (n=32) prior to each of two sessions of CET. Mechanistic outcomes were self-reported cravings and physiologic reactivity to smoking cues. The primary clinical outcome was 6-week, biochemically-verified, continuous tobacco abstinence.

DCS, relative to placebo, augmentation of CET resulted in lower self-reported craving to smoking pictorial and in vivo cues (d = 0.8 to 1.21) in a relevant subsample of participants who were reactive to cues and free from smoking-related reconditioning experiences. Select craving outcomes were correlated with smoking abstinence, and DCS augmentation was associated with a trend toward a higher continuous abstinence rate (33% vs. 13% for placebo augmentation).

DCS augmentation of CET can significantly reduce cue-induced craving, supporting the therapeutic potential of DCS augmentation when applied under appropriate conditions for adequate extinction learning.     

It’s All About Timing: An Imagery Intervention Examining Multiple Image Speed Combinations

The current quasi-experiment examined changes in youth baseball players’ (N = 9) swing performance following an imagery intervention. Athletes participated in one of three conditions, each of which employed a different combination of slow-motion (SM), real-time (RT), or fast-motion (FM) image speeds: SM?+?RT, RT?+?FM, or SM?+?RT?+?FM. A single-subject multiple-baseline design was employed. The intervention approximated the real-world environment in which baseball players practice, thus, increasing representative design. Results generally indicated positive changes across all three conditions, however, the SM?+?RT?+?FM condition exhibited the most improvement. The employment of a multiple-speed imagery intervention appears to be a viable option for young athletes.

Lay Summary: Can using a combination of slow-motion, real-time, and fast-motion imagery improve baseball batting performance? Our results suggest so! Learn more in “It’s all about timing: An imagery intervention examining multiple image speed combinations’ by @jennyo_csueb @Frank_O_Ely & @samagalas #JASP     

Juggalos - Whoop! Whoop! A Family or A Gang? A Participant-Observation Study on an FBI Defined ‘Hybrid’ Gang

ABSTRACT

This study examines the Juggalos and their controversial gang designation as defined by the Federal Bureau of Investigation. The Juggalos are devoted fans of the music group Insane Clown Posse, but law enforcement officials have identified Juggalos as a “hybrid” gang. A participant observation study was conducted in the fall of 2017 during the Juggalo March in Washington D.C. This protest rally was a response to challenge the gang classification and demonstrate to others that Juggalos are “a family and not a gang.” The authors observed Juggalo behaviors that were not consistent with a gang; but rather consistent with the characteristics of identifying a gang, as well as behaviors that were deviant.