Pre-training to find a hidden platform in the Morris water maze can compensate for a deficit to find a cued platform in a rat model of Parkinson's disease

The bilateral intranigral infusion of 1 micromol 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in adult male Wistar rats caused a specific and partial loss of substantia nigra pars compacta (SNc) dopamine neurons, a partial depletion of striatal dopamine, and a deficit to learn the intra-maze cued version of the Morris water maze. Pre-training the SNc rats in the spatial version of the water maze or simply maintaining the animals on the water maze platform reversed this deficit. This improvement was even observed when the order of the extra-maze cues presented to the rats during pre-training of the spatial version was changed during training of the intra-maze cued version. However, this deficit was not reversed either by maintaining the animals on the platform if the spatial cues were surrounded and covered with a curtain or by swimming sessions in the maze without the escape platform and the curtain. These findings suggest that none of the following elements alone, learned during the spatial task pre-training, could help SNc rats learn the intra-maze cued task: improvement of swimming skills or knowledge of the existence of the escape platform; distance between the platform and the border of the pool; location of a particular extra-maze cue; relations among extra-maze cues. However, the simultaneous presence of the escape platform and extra-maze cues (irrespective of their relational configuration) during the pre-training sessions proved to be necessary for this improving effect to occur.     

Secondary school pupils’ views of their school peer counselling for bullying service

Pupils (n=99) from two secondary schools in the UK were interviewed to investigate their views and experiences of the peer counselling for bullying service set up in their school. They were asked about various things concerning (1) the characteristics of the service and service providers that they valued and (2) their reasons for not using the service. Overall, a majority of participants reported a willingness to use this type of service and they identified numerous characteristics that they valued, including peer counsellors with good listening skills who were trustworthy and maintained confidentiality. A noteworthy proportion of participants also wanted the service to provide advice on solving bullying‐related problems. Some barriers to using the service were also identified, including fear of being stigmatised. Responses offered by girls and boys, and by users and non‐users of the service, were compared and several significant differences emerged. The results are discussed in terms of the implications for adults who run this type of service and the peer counsellors who deliver it.     

Are three-sample tasks less sensitive than two-sample tasks? Memory effects in the testing of taste discrimination

In order to provide insights into why discrimination protocols with three stimuli sometimes tend to be less sensitive than protocols with two stimuli, two experiments were conducted. In these experiments, the relative effects of memory decay and memory interference were investigated. Both experiments involved purified water and/or solutions of low NaCl concentration. In Experiment 1, three protocols were compared: the traditional same-different test (Protocol 1), the same protocol with a rinse between the two samples (Protocol 2), and Protocol 2 with an added time delay between the first sample and the intermediate rinse (Protocol 3.) The decrease in measured d' values as time delay increased indicated that memory decay might be a factor for tests with three stimuli, such as the triangle method, rendering it less sensitive than tests with two stimuli, such as the same-different method. In Experiment 2, four protocols were compared: the traditional same-different test, the two-rinse same-different test, the triangle test, and what will be called duo same-different test. The experimental design allowed the individual consideration of memory decay and interference effects. From this last experiment, the substantial effect of memory interference was uncovered. Further experimentation will be necessary to estimate the exact relative effects of memory interference and memory decay.     

Measuring the ability of transitive reasoning,using product and strategy information

Cognitive theories disagree about the processes and the number of abilities involved in transitive reasoning. This led to controversies about the influence of task characteristics on individuals' performance and the development of transitive reasoning. In this study, a computer test was constructed containing 16 transitive reasoning tasks having different characteristics with respect to presentation form, task format, and task content. Both product and strategy information were analyzed to measure the performance of 6- to 13-year-old children. Three methods (MSP, DETECT, and Improved DIMTEST) were used to determine the number of abilities involved and to test the assumptions imposed on the data by item response models. Nonparametric IRT models were used to construct a scale for transitive reasoning. Multiple regression was used to determine the influence of task characteristics on the difficulty level of the tasks. It was concluded that: (1) the qualitatively distinct abilities predicted by Piaget's theory could not be distinguished by means of different dimensions in the data structure; (2) transitive reasoning could be described by one ability, and some task characteristics influenced the difficulty of a task; and (3) strategy information provided a stronger scale than product information.     

The Assessment of Preterm Infants' Behavior (APIB): furthering the understanding and measurement of neurodevelopmental competence in preterm and full-term infants

The Assessment of Preterm Infants' Behavior (APIB) is a newborn neurobehavioral assessment appropriate for preterm, at risk, and full-term newborns, from birth to 1 month after expected due date. The APIB is based in ethological-evolutionary thought and focuses on the assessment of mutually interacting behavioral subsystems in simultaneous interaction with the environment. The subsystems of functioning assessed include the autonomic (respiration, digestion, color), motor (tone, movement, postures), state organization (range, robustness, transition patterns), attention (robustness, transitions), and self-regulation (effort, success) systems as well as the degree of facilitation required to support reorganization and subsystem balance. The environment is represented by a sequence of distal, proximal, tactile, and vestibular challenges, derived from the BNBAS. The APIB conceptualizes infant competence as the degree of differentiation of subsystem function and degree of modulation of subsystem balance at any stage in infant development. Infants are understood as actively seeking their next differentiation, while counting on good enough environments to assure progressing developmental competence. In the case of interference such as premature birth, the mismatch of expectation and actual experience causes misalignment, which may become developmentally costly. The assessment is a finely tuned dialogue between examiner and infant, which requires training, skill and self-knowledge. The APIB has well established inter-rater-reliability, concurrent and construct validity, and is clinically relevant for behavioral intervention and individually appropriate and supportive care.     

Spatial and object working memory impairments in schizophrenia patients: a Bayesian item-response theory analysis

This study reports evidence that schizophrenia patients are significantly impaired in both spatial and object (shape) working memory. A 3-s delay between exposure and recall of targets was used and Bayesian item-response theory was applied to compensate for the tasks' differential difficulty while simultaneously taking account of missing data from participant attrition. Weaker evidence was found that in schizophrenia both domains are equally impaired on average, that spatial and object working memory appear to be more highly correlated with each other in the schizophrenia population than in the normal population, and that schizophrenia patients show greater variability in spatial than object working memory performance.     

Mindfulness and negative affectivity in real time: a within-person process model

ABSTRACT

To extend our understanding of the proximal etiology of personality pathology, this study examined the dynamic, in-the-moment relations between mindfulness and negative affectivity (NA; emotional lability, anxiousness, separation insecurity) as defined by the alternative model for personality disorders. We tested predictions based upon the Monitor and Acceptance Theory that when people monitored their attention judgmentally, their state NA would be higher than usual; by contrast, when they monitored their attention nonjudgmentally, their state NA would be lower than usual. Sixty-five undergraduates participated in an experience sampling study wherein they completed five reports per day for eight days about their states of mindfulness and NA. Multi-level models revealed an interaction wherein participants exhibited more state NA when they monitored their attention judgmentally than when they monitored their attention nonjudgmentally. Analyses of simple slopes revealed that participants exhibited more state NA than usual when they monitored their attention judgmentally. These findings emerged for only one of two attention monitoring processes, however: monitoring relations between thoughts, emotions, and behaviours, but not monitoring sensory stimuli. Analyses including non-reactivity instead of nonjudgment replicated these findings. Implications for theory, research, and treatment are discussed.     

Televised Sexual Content and Parental Mediation: Influences on Adolescent Sexuality

Little research has been conducted to examine the influence of exposure to televised sexual content on adolescent sexuality or how parental intervention may reduce negative effects of viewing such content. This study uses self-report data from 1,012 adolescents to investigate the relations among exposure to sexually suggestive programming, parental mediation strategies, and three types of adolescent sexuality outcomes: participation in oral sex and sexual intercourse, future intentions to engage in these behaviors, and sex expectancies. As predicted, exposure to sexual content was associated with an increased likelihood of engaging in sexual behaviors, increased intentions to do so in the future, and more positive sex expectancies. Often, parental mediation strategies were a significant factor in moderating these potential media influences.     

Latent Class Modeling of Phases in the Development of Transitive Reasoning

Fuzzy trace theory posits that during development the use of verbatim information for solving transitive relationships shifts to the use of gist information. In cognitive developmental research that uses a cross-sectional design, the binomial mixture model is often used to identify such shifts. Because the binomial mixture model assumes equal task difficulty and uses the number of correctly solved tasks for data analysis, it may be too restrictive and the more flexible latent class model is adopted as an alternative. This model allows varying task difficulty and uses the pattern of task scores as input for data analysis. The binomial mixture model and the latent class model are compared theoretically, and applied to transitive reasoning test data obtained from a cross-sectional sample of 615 children. The latent class model is found to be more appropriate for identifying multiple phases. Three phases are distinguished which can be interpreted well by means of fuzzy trace theory. These phases do not encompass fixed age periods.     

Occurrence of imagery and its link with early memories in agoraphobia

Recent cognitive models suggest that mental imagery can help us understand the maintenance of anxiety disorders (e.g., de Silva, 1986; Hackmann, Surawy, & Clark, 1998). However, imagery is relatively unexplored within agoraphobia. Such images are also thought to be useful in uncovering memories that occurred around the onset of a disorder (Hackmann, Clark, & McManus, 2000). A total of 20 patients with agoraphobia and 20 matched controls took part in this investigation. Participants described any recurrent images they experienced in agoraphobic situations, and also any associated memories. All patients with agoraphobia (but no control participants) reported having distinct recurrent images in “agoraphobic situations”. Most images involved several sensory modalities and in the majority of cases appeared to be linked with unpleasant memories of events experienced many years previously. While these exploratory findings require replication, potential treatment implications are discussed.