When the social self is threatened: shame, physiology, and health

Our program of research focuses on shame as a key emotional response to "social self" threats (i.e., social evaluation or rejection). We propose that shame may orchestrate specific patterns of psychobiological changes under these conditions. A series of studies demonstrates that acute threats to the social self increase proinflammatory cytokine activity and cortisol and that these changes occur in concert with shame. Chronic social self threats and persistent experience of shame-related cognitive and affective states predict disease-relevant immunological and health outcomes in HIV. Across our laboratory and longitudinal studies, general or composite affective states (e.g., distress) are unrelated to these physiological and health outcomes. These findings support a stressor- and emotional response-specificity model for psychobiological and health research.     

Restraint stress and corticotropin releasing hormone modulation of murine cutaneous POMC mRNA

The skin is a unique immunological defense barrier that protects the organism from occupational and environmental exposures and provides a model system in which to evaluate the interaction of the central nervous system with the peripheral immune response. In the studies presented here, we tested mild, acute restraint stress activation of the cutaneous corticotropin releasing hormone-pro-opiomelanocortin (CRH-POMC) axis. We verified that 2 h restraint stress increased the serum concentration of corticosterone and alpha-melanocyte stimulating hormone. We report for the first time that CRH upregulates POMC mRNA expression in mouse skin in vitro. We also demonstrated, by RT-PCR, that 2,4 di-nitrofluorobenzene (DNFB) upregulates cutaneous POMC mRNA expression, the production of which is suppressed by restraint stress. These data confirm the presence and functionality of two hormones of the hypothalamo-pituitary axis in the skin and suggest that activation of the central hypothalamo-pituitary-adrenal axis may over ride activation of the cutaneous CRH-POMC mechanism in the development of DNFB-stimulated allergic contact dermatitis.     

Orientation discrimination across the visual field: size estimates near contrast threshold

Performance in detection and discrimination tasks can often be made equal across the visual field through appropriate stimulus scaling. The parameter E2 is used to characterize the rate at which stimulus dimensions (e.g., size or contrast) must increase in order to achieve foveal levels of performance. We calculated both size and contrast E2 values for orientation discrimination using a spatial scaling procedure that involves measuring combination size and contrast thresholds for stimuli with constant size-to-contrast ratios. E2 values for size scaling were 5.77 degrees and 5.92 degrees. These values are three to four times larger than those recovered previously using similar stimuli at contrasts well above detection threshold (Sally & Gurnsey, 2003). E2 values for contrast scaling were 324.2 degrees and 44.3 degrees, indicating that for large stimuli little contrast scaling (.3% to 2.3% increase) was required in order to equate performance in the fovea and the largest eccentricity (10 degrees). A similar pattern of results was found using a spatial scaling method that involves measuring contrast thresholds for target identification as a function of size across eccentricities. We conclude that the size scaling for orientation discrimination at near-threshold stimulus contrasts is much larger than that required at suprathreshold contrasts. This may arise, at least in part, from contrast-dependent changes in mechanisms that subserve task performance.     

Family expressiveness and parental emotion coaching: their role in children's emotion regulation and aggression

In this study, we explored the relations between positive and negative family expressiveness, parental emotion coaching, child emotion regulation, and child aggression. The sample included 120 fourth-grade children and their mothers. Mothers completed the Emotion Regulation Checklist, the Family Expressiveness Questionnaire, and a portion of the meta-emotion interview to assess their awareness and acceptance of, and instruction in managing their child's anger and sadness (3 dimensions of parental emotion coaching). Teachers rated each child's aggression and completed the Emotion Regulation Checklist for each child. The 3 dimensions of parental emotion coaching and positive and negative family expressiveness were not directly related to child aggression. However, both negative family expressiveness and the mother's acceptance of the child's negative emotions were indirectly related to child aggression through the child's emotion regulation.     

The impact of domestic violence on mothers' prenatal representations of their infants

This study examined the relationship between domestic violence during pregnancy and mothers' prenatal representations of their infants and themselves as mothers. Two hundred and six women were recruited from the community and interviewed during their last trimester of pregnancy. Forty‐four percent of women reported experiencing domestic violence during the current pregnancy, while 56% reported no domestic violence during the pregnancy. Maternal representations were assessed using the Working Model of the Child Interview (WMCI; Zeanah, Benoit, Hirshberg, Barton, & Regan, 1994). Multiple analysis of variance (MANCOVA) and χ² analyses revealed that women who experienced domestic violence had significantly more negative representations of their infants and themselves as mothers and were significantly more likely to be classified as insecurely attached (either Disengaged or Distorted) than women who had not experienced domestic violence. These results, along with several excerpts from battered women's interviews, highlight the importance of domestic violence as a risk factor for maternal and infant well being. These findings and their clinical implications are discussed in light of attachment theory. ©2004 Michigan Association for Infant Mental Health.     

Common neural systems associated with the recognition of famous faces and names: An event-related fMRI study

Person recognition can be accomplished through several modalities (face, name, voice). Lesion, neurophysiology and neuroimaging studies have been conducted in an attempt to determine the similarities and differences in the neural networks associated with person identity via different modality inputs. The current study used event-related functional-MRI in 17 healthy participants to directly compare activation in response to randomly presented famous and non-famous names and faces (25 stimuli in each of the four categories). Findings indicated distinct areas of activation that differed for faces and names in regions typically associated with pre-semantic perceptual processes. In contrast, overlapping brain regions were activated in areas associated with the retrieval of biographical knowledge and associated social affective features. Specifically, activation for famous faces was primarily right lateralized and famous names were left-lateralized. However, for both stimuli, similar areas of bilateral activity were observed in the early phases of perceptual processing. Activation for fame, irrespective of stimulus modality, activated an extensive left hemisphere network, with bilateral activity observed in the hippocampi, posterior cingulate, and middle temporal gyri. Findings are discussed within the framework of recent proposals concerning the neural network of person identification.     

Environmental Influences on Fighting Versus Nonviolent Behavior in Peer Situations: A Qualitative Study with Urban African American Adolescents

This qualitative study explored environmental factors that influence adolescents’ responses to problem situations involving peers. Interviews were conducted with 106 middle school students (97% African American) from an urban school system. Participants were asked to describe factors that would make it easier and those that would make it more difficult for adolescents to make specific responses to problem situations. Two types of responses were presented: nonviolent responses identified as effective in a previous study, and fighting responses. Qualitative analysis identified 24 themes representing family, peer, school, and neighborhood and broader social factors that were related to both nonviolent behavior and fighting. The identification of environmental influences on fighting and nonviolent responses has important implications for efforts to reduce aggression and promote effective nonviolent responses to problem situations encountered by adolescents.     

An Examination of Two Techniques for Promoting Response Generalization of Early Literacy Skills

This study examined the application of two generalization procedures designed to promote generalized responding across two early literacy skills. Letter sound fluency was targeted using direct intervention for three subjects within a multiple baseline design. After instruction was complete, two generalization procedures (cueing and providing sufficient response exemplars) were tested in an increasingly intense application of the procedures to determine whether sufficient levels of response generalization to letter sound blending could be programmed. Results indicated that although some subjects demonstrated minor levels of unprogrammed or spontaneous generalization, more complete levels of generalization were accomplished only once generalization techniques were employed.     

The influence of T-shirt graphics on perceptions and behavioral intentions

Do graphics on clothing drive perceptions? We used a between group design to test if athletic, academic, or suggestive graphics on clothing differentially influence perceptions and behavioral intentions. In study 1, participants (N = 199) rated five female t-shirt models, and in study 2 and 3, participants rated five male t-shirt models (N = 120) or university students (N = 50). Analyses of variance controlling for sex (ANCOVA) showed participants were least likely to want to interact with models/students wearing sexually suggestive graphics: Study 1, F(3,165) = 30.263, p < .001, η_p ²  = .30, power = 1.00; Study 2, F (3,119) = 11.630, p < .000, η_p ² = .234, and Study 3, F(1, 42) = 12.578, p < .000. Participants did not rate models in the academic and athletic graphic shirts differently from models with plain white shirts. Results support the concept that people form different perceptions based upon the clothing a person wears, changing behavioral intentions. Neither sex role ideation (Study 1) or sexism (Study 2) were significant covariates of perceptions and intentions.