Caregiver- and Clinician-Reported Adaptive Functioning in Rett Syndrome: a Systematic Review and Evaluation of Measurement Strategies

Neuropsychology Review - Rett syndrome is the second most common cause of intellectual disability in females worldwide. The severity of many individuals’ impairment limits the effectiveness...     

Prior probability modulates anticipatory activity in category-specific areas

Bayesian models are currently a dominant framework for describing human information processing. However, it is not clear yet how major tenets of this framework can be translated to brain processes. In this study, we addressed the neural underpinning of prior probability and its effect on anticipatory activity in category-specific areas. Before fMRI scanning, participants were trained in two behavioral sessions to learn the prior probability and correct order of visual events within a sequence. The events of each sequence included two different presentations of a geometric shape and one picture of either a house or a face, which appeared with either a high or a low likelihood. Each sequence was preceded by a cue that gave participants probabilistic information about which items to expect next. This allowed examining cue-related anticipatory modulation of activity as a function of prior probability in category-specific areas (fusiform face area and parahippocampal place area). Our findings show that activity in the fusiform face area was higher when faces had a higher prior probability. The finding of a difference between levels of expectations is consistent with graded, probabilistically modulated activity, but the data do not rule out the alternative explanation of a categorical neural response. Importantly, these differences were only visible during anticipation, and vanished at the time of stimulus presentation, calling for a functional distinction when considering the effects of prior probability. Finally, there were no anticipatory effects for houses in the parahippocampal place area, suggesting sensitivity to stimulus material when looking at effects of prediction.     

Impact of Genomic Counseling on Informed Decision-Making among ostensibly Healthy Individuals Seeking Personal Genome Sequencing: the HealthSeq Project

Personal genome sequencing is increasingly utilized by healthy individuals for predispositional screening and other applications. However, little is known about the impact of ‘genomic counseling’ on informed decision-making in this context. Our primary aim was to compare measures of participants’ informed decision-making before and after genomic counseling in the HealthSeq project, a longitudinal cohort study of individuals receiving personal results from whole genome sequencing (WGS). Our secondary aims were to assess the impact of the counseling on WGS knowledge and concerns, and to explore participants’ satisfaction with the counseling. Questionnaires were administered to participants (n = 35) before and after their pre-test genomic counseling appointment. Informed decision-making was measured using the Decisional Conflict Scale (DCS) and the Satisfaction with Decision Scale (SDS). DCS scores decreased after genomic counseling (mean: 11.34 before vs. 5.94 after; z = ?4.34, p < 0.001, r = 0.52), and SDS scores increased (mean: 27.91 vs. 29.06 respectively; z = 2.91, p = 0.004, r = 0.35). Satisfaction with counseling was high (mean (SD) = 26.91 (2.68), on a scale where 6 = low and 30 = high satisfaction). HealthSeq participants felt that their decision regarding receiving personal results from WGS was more informed after genomic counseling. Further research comparing the impact of different genomic counseling models is needed.     

Predictors of children's entertainment television viewing: Why are they tuning in?

Three hundred and twenty six 3- and 5-year-olds (N = 160 3-year-olds) participated in a longitudinal study of the sociological and ecological predictors of children's general audience and child entertainment viewing. Viewing was assessed through five weekly diaries for each child, completed by families over a two-year period. Concurrent analyses of program availability, family demographics/attributes, and child characteristics indicated that children who were frequent viewers of entertainment programs had parents who had limited education, access to cable, and incorporated television into their activities. Although parental regulation and encouragement played a role in children's viewing experiences, particularly at 5 and 7 years of age, the strongest long-term predictors on children's entertainment viewing were parents' education, family size, and the age and sex of the child. Parents need to become more aware of their role in shaping their children's viewing habits. Responsibility for improving children's television viewing experiences, however, should not rely solely with parents but must be shared by educators, broadcasters, and legislators.     

Life Tasks and Daily Life Experience

ABSTRACT This article explores the assumption that the goals on which an individual works structure the experience of daily life. One set of important goals are those consensual tasks that reflect the age-graded expectations of a living environment (e.g., the task of being on one's own at college). Whereas most members of a common age group share these consensual life tasks, individuals in a group differ in the relative importance they place on different tasks and in their appraisals of them. In the present study of 54 women living in a college sorority, the importance of a life task was associated with increased relevance of the task to daily life events, as revealed in experience sampling. The women were more emotionally involved in events that they saw as highly relevant to their life tasks than in less relevant events and, for each person, positive affect and emotional involvement in task-relevant events were related to her initial life task appraisals.     

A pawn by any other name? Social information processing as a function of psychopathic traits

Past research has linked psychopathic traits with the ability to manipulate others, either through deception or violence. Recent observations in corporate settings suggest that enhanced interpersonal assessments might underlie this process, giving psychopathic individuals the ability to detect useful and/or vulnerable victims. To test this hypothesis, a non-forensic sample of males participated in a social memory experiment involving the recognition of faces and recalling the biographical details of artificially created characters differing in their relative career success and emotional vulnerability. High-psychopathy participants had near-perfect recognition for sad, unsuccessful female characters, but impaired memory for other characters. The findings suggest that psychopathic personality is associated with “predatory memory” even in the absence of overt criminality.     

Further Evidence for Reliability and Validity of the Triarchic Psychopathy Measure in a Forensic Sample and a Community Sample

Psychopathy is often described as a constellation of personality characteristics encompassing features such as impulsivity and antisociality, and a lack of empathy and guilt. Although the use of self-reports to assess psychopathy is still debated, there are distinct advantages to such measures and recent research suggests that they may not be as problematic as previously thought. This study further examined the reliability and validity of the Triarchic Psychopathy Measure (TriPM) in a community sample (N = 496) and forensic psychiatric patient sample (N = 217). Results indicated excellent internal consistencies. Additionally, the TriPM total and subscale scores related as expected to different subscales of the Psychopathic Personality Inventory –Revised (PPI-R) and to the Reactive and Proactive Aggression Questionnaire, reflecting good construct validity. Most importantly, ROC curve analyses showed that the TriPM evidenced better discrimination between the community sample and forensic psychiatric patients than the PPI-R. The current study extends the existent evidence demonstrating that the TriPM can be used as an efficient self-report instrument.     

Element repetition rates encode functionally distinct information in pied babbler ‘clucks’ and ‘purrs’

Human language is a recombinant system that achieves its productivity through the combination of a limited set of sounds. Research investigating the evolutionary origin of this generative capacity has generally focused on the capacity of non-human animals to combine different types of discrete sounds to encode new meaning, with less emphasis on meaning-differentiating mechanisms achieved through potentially simpler temporal modifications within a sequence of repeated sounds. Here we show that pied babblers (Turdoides bicolor) generate two functionally distinct vocalisations composed of the same sound type, which can only be distinguished by the number of repeated elements. Specifically, babblers produce extended ‘purrs’ composed of, on average, around 17 element repetitions when drawing young offspring to a food source and truncated ‘clucks’ composed of a fixed number of 2–3 elements when collectively mediating imminent changes in foraging site. We propose that meaning-differentiating temporal structuring might be a much more widespread combinatorial mechanism than currently recognised and is likely of particular value for species with limited vocal repertoires in order to increase their communicative output.