Habit reversal versus supportive psychotherapy in Tourette's disorder: a randomized controlled trial and predictors of treatment response

Tourette syndrome (TS) is characterized by chronic motor and vocal tics. Habit reversal therapy (HR) is a behavioral treatment for tics which has received recent empirical support. The present study compared the efficacy of HRT in reducing tics, improving life-satisfaction and psychosocial functioning in comparison with supportive psychotherapy (SP) in outpatients with TS. In addition, we investigated whether impairments in response inhibition in patients with TS predict response to HR treatment which specifically aims to inhibit tics. Thirty adult outpatients with DSM-IV TS were randomized to 14 individual sessions of HR (n = 15); or SP (n = 15). HR but not SP reduced tic severity over the course of the treatment. Both groups improved in life-satisfaction and psychosocial functioning during active treatment. Reductions in tic severity (HR) and improvements in life-satisfaction and psychosocial functioning (HR and SP) remained stable at the 6-month follow-up. The extent of pre-treatment response inhibition impairment in the HR group predicted reductions in tic-severity from pre- to post-treatment. Our results suggest that HR has specific tic-reducing effects although SP is effective in improving life-satisfaction and psychosocial functioning. Assessments of response inhibition may be of value for predicting treatment response to HR.     

Intact emotion-induced recognition bias in neuropsychological patients with executive control deficits

In recognition memory tasks, emotionally negative words are judged more often as "old" relative to emotionally neutral words, suggesting a shift in response bias. We wondered whether this bias shift was due to the flexible regulation of executive control during memory retrieval. To address this question, we investigated individuals with high variability in executive control functions. As expected, we observed that emotional word meaning did indeed have a strong influence on the bias toward responding "old," independent of recognition accuracy and overall response bias. However, these effects were uncorrelated with executive control, as measured by the Trail Making Test, and were fully intact, even in a sample of hospitalized neurological patients with severe executive dysfunctions, some of whom had marked damage in fronto-thalamo-striatal networks. Having concluded that the emotion-induced bias must develop on different grounds, we went on to discuss alternative explanations.     

Job characteristics and off-job activities as predictors of need for recovery, well-being, and fatigue

Two empirical studies examined need for recovery (i.e., a person's desire to be temporarily relieved from demands in order to restore his or her resources) as a mediator in the relationship between poor job characteristics (high job demands, low job control) and high off-job demands, on the one hand, and fatigue and poor individual well-being, on the other hand. Multilevel data from a daily survey study in the health service sector (Study 1) showed that high job demands, low job control, and unfavorable off-job activities predicted a high need for recovery. Need for recovery in turn was negatively related to individual well-being. A large-scale survey with a representative sample of the Dutch working population (Study 2) confirmed these findings for fatigue. In both studies, need for recovery mediated the effects of job characteristics and off-job activities on fatigue and poor well-being, respectively.     

Overlapping mental representations of self, ingroup, and outgroup: unraveling self-stereotyping and self-anchoring

Smith and collaborators presented strong response time evidence for overlapping mental representations of the self and relevant ingroups, and they interpreted their findings as reflecting that people define themselves in terms of their ingroups. Besides on inferences from ingroup to self (self-stereotyping) however, self-ingroup overlap could also be based on inferences from the self to the ingroup (self-anchoring). The present research tackled this interpretational ambiguity and empirically distinguished self-anchoring versus self-stereotyping as processes possibly under-lying self-ingroup overlap. Results from three studies revealed stronger evidence for inferences from self to ingroup (selfanchoring) than the other way round (self-stereotyping).     

Memory consolidation for the discrimination of frequency-modulated tones in mongolian gerbils is sensitive to protein-synthesis inhibitors applied to the auditory cortex

Differential conditioning of Mongolian gerbils to linearly frequency-modulated tones (FM) has recently received experimental attention. In the study of the role of cerebral protein synthesis for FM discrimination memory, gerbils received post-training bilateral injections of anisomycin into the auditory cortex under light halothane anesthesia. Compared with saline-treated controls, anisomycin-treated gerbils showed a discrimination decrement during the subsequent three days of training. They markedly improved their performance within training sessions, but started each session at low levels. When repeatedly trained gerbils received post-session injections of anisomycin, discrimination performance during subsequent sessions was similar to the pre-injection performance, indicating that retention, retrieval, reconsolidation, and expression of the established reaction were not affected. However, the improvement of a partially established discrimination reaction was impaired after this treatment. Intracortical injections of emetine confirmed this finding. Neither drug affected FM discrimination learning when given several days before the initial training. Our results suggest that protein-synthesis inhibitors applied to the auditory cortex of gerbils during the post-acquisition phase interfered with learning and memory-related aspects of FM processing. The resulting deficit was evident for a number of post-injection training days. This effect was probably due to impaired consolidation, i.e., processes required for long-term stabilization or retrieval of the memory trace while leaving short-term memory intact.     

Interpretive biases for ambiguous information in body dysmorphic disorder

Anxiety-disordered patients and individuals with high trait anxiety tend to interpret ambiguous information as threatening. The purpose of this study was to investigate whether interpretive biases would also occur in body dysmorphic disorder (BDD), which is characterized by a preoccupation with imagined defects in one's appearance. We tested whether BDD participants, compared with obsessive-compulsive disorder participants and healthy controls, would choose threatening interpretations for ambiguous body-related, ambiguous social, and general scenarios. As we hypothesized, BDD participants exhibited a negative interpretive bias for body-related scenarios and for social scenarios, whereas the other groups did not. Moreover, both clinical groups exhibited a negative interpretive bias for general scenarios.     

Dissociating prelexical and postlexical processing of affective information in the two hemispheres: effects of the stimulus presentation format

Using a lexical decision task, the authors investigated whether brain asymmetries in the detection of emotionally negative semantic associations arise only at a perceptually discriminative stage at which lexical analysis is accurate or can already be found at crude and incomplete levels of perceptual representation at which word-nonword discrimination is based solely on guessing. Emotionally negative and neutral items were presented near perceptual threshold in the left and right visual hemifields. Word-nonword discrimination performance as well as the bias to classify a stimulus as a "word" (whether or not it actually is a word) were assessed for a normal, horizontal stimulus presentation format (Experiment 1) and for an unusual, vertical presentation format (Experiment 2). Results show that while the two hemispheres are equally able to detect affective semantic associations at a prelexical processing stage (both experiments), the right hemisphere is superior at a postlexical, perceptually discriminative stage (Experiment 2). Moreover, the findings suggest that only an unusual, nonoverlearned stimulus presentation format allows adequate assessment of the right hemisphere's lexical-semantic skills.     

Psycholinguistics: a half century of monologism

The contention of this article is that, since its inception in the mid-twentieth century, mainstream psycholinguistics has been monologistic, that is, has concentrated on monologue as its source of empirical material and has, largely implicitly, involved a monologistic epistemology. The article is not a comprehensive history of psycholinguistics but does attempt to establish a historical perspective. Monologism has been the historical bias of Cartesianism, positivism, behaviorism, and cognitivism. Monologism is concerned only with the person in whom cognition takes place and from whom communication proceeds. It is essentially asocial. By contrast, the merits of dialogism include an openness to the sociocultural, interactive nature of all cognition and communication and an empirical engagement of contextualized discourse situations. Dialogism is presented here not as a supplement to mainstream psycholinguistics but as a radical innovation that construes mainstream psycholinguistics as "strongly misleading if presented as a full theory of communication through spoken interaction" (Linell, 1998, p. 23). Some approaches to dialogism and research on dialogue are critically reviewed.     

Pre-service teachers’ implicit and explicit attitudes toward obesity influence their judgments of students

Obese children experience disadvantages in school and discrimination from their teachers. Teachers’ implicit and explicit attitudes have been identified as contributing to these disadvantages. Drawing on dual process models, we investigated the nature of pre-service teachers’ implicit and explicit attitudes, their motivation to respond without prejudice, and how attitudes influence their judgments of an obese student. Results showed that implicit anti-obesity bias might stem from an implicit positivity toward thinness rather than from an implicit negativity toward obesity. Explicit attitudes were mixed: positive attitudes toward achievement, a dislike of obese persons, and neutral attitudes concerning blame and health responsibility emerged. Implicit and explicit attitudes affected judgments of language proficiency and intelligence: pre-service teachers with more positive attitudes judged the obese student more favorably. The results of multiple regression analyses suggest that attitudes might exert a greater influence when pre-service teachers must draw inferences to derive the judgment.