论梁漱溟乡村建设中的政治伦理思想

梁漱溟的乡村建设运动是其道德理想的直接践履,更是其复兴中国、推贤治国政治伦理思想的现实表达,梁漱溟认为中国政治的失败根本上源于传统文化遭到巨大破坏,以及中国没有形成真正的政治文化,要实现中国政治的复兴与强大,必须建立政教合一的政治体制,并充分发挥知识分子的作用,实现知识分子与农民的结合。     

Should We Treat Depression with drugs or psychological interventions? A Reply to Ioannidis

We reply to the Ioannidis's paper "Effectiveness of antidepressants; an evidence based myth constructed from a thousand controlled trials." We disagree that antidepressants have no greater efficacy than placebo. We present the efficacy from hundreds of trials in terms of the percentage of patients with a substantial clinical response (a 50% improvement or more symptomatic reduction). This meta-analysis finds that 42-70% of depressed patients improve with drug and 21%-39% improve with placebo. The response benefit of antidepressant treatment is 33%-11% greater than placebo. Ioannidis argues that it would be vanishingly smaller because systematic biasing in these clinical trials would reduce the drug-placebo difference to zero. Ioannidis' argument that antidepressants have no benefit is eroded by his failures of logic because he does not present any evidence that there are a large number of studies where placebo is substantially more effective than drug. (To reduce to zero, one would also have to show that some of the unpublished studies find placebo better than drug and have substantial systematic or methodological bias). We also present the empirical evidence showing that these methodological concerns generally have the opposite effect of what Ioannidis argues, supporting our contention that the measured efficacy of antidepressants likely underestimates true efficacy. Our most important criticism is Ioannidis’ basic underlying argument about antidepressants that if the existing evidence is imperfect and methods can be criticized, then this proves that antidepressant are not efficacious. He presents no credible evidence that antidepressants have zero effect size. Valid arguments can point out difficulties with the data but do not prove that a given drug had no efficacy. Indeed better evidence might prove it was more efficacious that originally found. We find no empirical or ethical reason why psychiatrists should not try to help depressed patients with drugs and/or with psychotherapeutic/behavioral treatments given evidence of efficacy even though our treatment knowledge has limitations. The immense suffering of patients with major depression leads to ethical, moral, professional and legal obligations to treat patients with the best available tools at our disposal, while diligently and actively monitoring for adverse effects and actively revising treatment components as necessary.     

现代性弊端及其超越:毛泽东的“革命”方案

毛泽东的"革命",既是一场驱动着古老中国由传统走向现代的卓绝的努力,同时又强烈地体现出对于"现代性"弊端进行反拨的价值维度:针对现代性过程极易产生的官僚主义政治体制的弊端,他试图通过一场全方位的文化大革命实现权力重组,以巩固其人民民主的政治体制;针对现代性过程中所带来的片面的发展主义的经济模式,他试图通过"抓革命、促生产"来寻找一个"发展"和"公正"的结合点;针对现代性过程中出现的文化精英主义倾向,他试图通过对知识分子再教育来破解精英与大众的对立这一历史性难题。在带领中国走向现代化的过程中致力于超越西方现代性的弊端,进而创造出一种新的社会现代化方案,成为毛泽东"革命"的一个重要主题。     

防御性医疗行为的分类探讨

医患矛盾加剧的今天,医疗纠纷逐年增加,为了避免医疗纠纷,医生采取防御性医疗行为也不断随之增多.防御性医疗行为的存在是否具有合理性,成为探讨的焦点和难点.本文通过对防御性医疗行为的分类标准和分类类型进行探讨,希望对其合理与否的论证提供重要参考,且希望通过对它的分类更好的为其行使原则及后果的责任研究作下一步铺垫.     

溶栓后PCI,从不行到可行

再灌注治疗STEMI的方法有直接PCI和溶栓。我国各地医疗条件差别较大,只有12%的STEMI患者能够及时接受直接PCI,超过半数的患者仍行溶栓治疗,故溶栓在我国再灌注策略中占有重要地位。虽然溶栓后即刻PCI即易化PCI被证实不如直接PCI,但溶栓并非STEMI治疗的终点。目前国外循证证据显示溶栓后早期转运PCI优于溶栓失败后再转运行补救PCI,值得我国借鉴学习。     

闪光滞后效应并非知觉延迟差异所致

闪光滞后效应(flash-lag effect)是指在与运动物体一致的位置上呈现闪光(flash),知觉上闪光落后于运动物体的视错觉。延迟差异理论认为,产生该现象的原因是视觉系统加工闪光的速度比加工运动物体慢。根据该理论,作者预测:如采用知觉加工速度更快(或更慢)的客体替代闪光,应能相应地产生更小(或更大)的闪光滞后效应。为了检验该预测,作者以"客体突现"(onset)和"客体消失"(offset)替代闪光滞后实验中的闪光,结果发现,"突现"的知觉滞后大于"消失",但时序判断任务表明"突现"的知觉延迟比"消失"短。该结果并不支持延迟差异理论。     

创造力的脑结构与脑功能基础

从脑结构和脑功能两方面对创造力的脑神经基础进行了评述。就创造力的脑结构而言,尸体脑解剖研究表明创造力可能与顶叶与角回有关;活体脑结构成像研究则显示,创造力主要与额叶、扣带回以及皮下白质或灰质浓度有关。就创造力的脑功能而言,任务取向研究表明创造力任务主要激活了额叶和顶叶及少数其他皮层区域;而个体差异取向研究则表明创造力被试激活了右侧额叶、大脑皮层以及小脑的某些区域。未来研究需在加强脑结构影像研究基础上,注重从被试抽样和筛选等方面细化任务模式和个体差异模式的创造力研究,以获得更一致的结果。     

言语和非言语信号加工的早期分离——来自ERP研究的证据

利用128导事件相关电位技术,对19名正常被试在言语、峰鸣声和音乐刺激上产生的脑电早期外源性成分N1进行了考察。实验结果发现,在音素条件和蜂鸣声条件下,左侧额叶N1波幅显著高于右侧。偶极子溯源分析发现音素条件和蜂鸣声条件下的偶极子都位于左脑额叶,而音乐条件下的两个偶极子位于右脑额叶。证明范畴属性对信号加工大脑半球优势的影响在加工的早期就开始发挥作用。     

“Outside thinking” and “Horizontal logic”

Metaphysics is a repeated act by way of “representation”; the instantaneous judgment is solidified, the inevitable conclusion is made, and at the same time other possibilities are excluded. “Outside thinking” is a blow to the spiritual tradition of metaphysics, which holds that “representation” will lead to a differential activity concerning the relationship between stranger things. Such relationship follows a kind of “horizontal logic,” the latter discards the presupposition on the “origin” of things, that is, it no longer presumes that this point or that point has greater privilege than “other points.” Things do not develop from a central point. Rather, things are the result of innumerable “points” in cooperative relationships between strangers. These cooperative relationships are arbitrary. In “horizontal logic,” many “starting points” or “spiritual T-points” are used as substitutes for a unique “origin.”     

基督教“道德金律”与康德的道德律令

康德为道德寻求客观依据而确立的"道德律令"继承了基督教传统"道德金律"的普世性、律法及上帝观念,同时又从实践理性角度赋予了这种基督教传统文化思想以新的时代意义。这种新的解释具有现代科学理性及人文性特征,从而对后之学者在道德问题上的探寻有着深远的影响。