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991.
Dana-Farber Cancer Institute ethics rounds: life-threatening illness and the desire to adopt 总被引:1,自引:0,他引:1
Little MO Moczynski WV Richardson PG Joffe S 《Kennedy Institute of Ethics journal》2005,15(4):385-393
Originally presented during Ethics Rounds at the Dana-Farber Cancer Institute, this commentary on the case of a patient treated for life-threatening cancer explores the responsibilities of health care providers when addressing the patient's desire to adopt a child. 相似文献
992.
In a first stage of training, participants learned to associate four visual cues (two different colors and two different shapes)
with verbal labels. For Group S, one label was applied to both colors and another to both shapes; for Group D, one label was
applied to one color and one shape, and the other label to the other cues. When subsequently required to learn a task in which
a given motor response was required to one of the colors and one of the shapes, and a different response to the other color
and the other shape, Group D learned more readily than Group S. The task was designed so that the associations formed during
the first stage of training could not generate differential transfer to the second stage. The results are consistent, however,
with the proposal that training in which similar cues are followed by different outcomes will engage a learning process that
boosts the attention paid to features that distinguish these cues. 相似文献
993.
In the Implicit Association Test (IAT; Greenwald, McGhee, & Schwartz, 1998) involving race classification (white vs. black),
an apparent compatibility effect is found between the “pleasant” attribute and the “white” category. This race IAT effect
has been interpreted in terms of “implicit prejudice”—that is, more positive evaluation of whites than of blacks that is not
open to consciousness. We suggested instead that the race IAT effect is better interpreted in terms of the salience asymmetry
account proposed by Rothermund and Wentura (2004), whereby greater familiarity with the white category makes it more salient.
Evidence that has been presented against the familiarity interpretation is considered, and alternative interpretations of
findings related to the race IAT effect are discussed. 相似文献
994.
To continue research assessing the validity of the Balloon Analog Risk Task (BART) as a measure of risk taking, the BART was administered to a nonforensic sample of individuals with varying levels of psychopathic characteristics. Construct validity of the BART was evaluated by measuring risk-taking behavior in relation to self-reported psychopathy, anxiety, psychophysiological data, and demographic variables. Supporting the construct validity of the BART, while controlling for variance accounted for by interrelated variables in the context of hierarchical regression analyses, higher self-reported psychopathy was significantly predictive of increased risk taking on the BART. Findings also revealed interesting gender differences in self-reported psychopathy and a trend for men to engage in riskier behavior. Limitations and research directions are presented. 相似文献
995.
This study evaluated the structural reliability, construct-related validity, and cultural validity generalization of the Hare Psychopathy Checklist: Screening Version (PCL:SV) in a sample of more than 560 male and female Swedish forensic psychiatric treatment patients, forensic evaluation patients, and criminal offenders. Structural reliability was excellent for most indices. PCL:SV scores were higher for males than females for total and Part 1 scores (interpersonal/affective features) but not for Part 2 (behavioral features). With some exceptions, PCL:SV scores were meaningfully related to aggression to others, a measure of risk for violence, substance use problems, personality disorder (positive), and psychosis (negative). Correlations between PCL:SV and aggression were larger for females than males, although the difference was smaller when personality disorder was held constant. The structural reliability and pattern of validity coefficients were comparable in these Swedish samples to other non-North American samples. Implications for the cross-cultural manifestation and correlates of psychopathy are discussed. 相似文献
996.
Enhancement of auditory fear conditioning after housing in a complex environment is attenuated by prior treatment with amphetamine 下载免费PDF全文
Prior exposure to drugs of abuse has been shown to occlude the structural plasticity associated with living in a complex environment. Amphetamine treatment may also occlude some cognitive advantages normally associated with living in a complex environment. To test this hypothesis we examined the influence of prior exposure to amphetamine on fear conditioning in rats housed in either a standard or complex environment. Housing in a complex environment facilitated fear learning to an auditory conditioned stimulus (CS), but not to the training context, relative to animals housed singly or in a social group. Prior treatment with amphetamine eliminated this effect. These results indicate that living in a complex environment facilitates conditional freezing to an auditory CS, and that this effect is abolished by pretreatment with amphetamine. 相似文献
997.
Acetylcholine release in the hippocampus and striatum during place and response training 总被引:3,自引:0,他引:3 下载免费PDF全文
Pych JC Chang Q Colon-Rivera C Haag R Gold PE 《Learning & memory (Cold Spring Harbor, N.Y.)》2005,12(6):564-572
These experiments examined the release of acetylcholine in the hippocampus and striatum when rats were trained, within single sessions, on place or response versions of food-rewarded mazes. Microdialysis samples of extra-cellular fluid were collected from the hippocampus and striatum at 5-min increments before, during, and after training. These samples were later analyzed for ACh content using HPLC methods. In Experiment 1, ACh release in both the hippocampus and striatum increased during training on both the place and response tasks. The magnitude of increase of training-related ACh release in the striatum was greater in rats trained on the response task than in rats trained on the place task, while the magnitude of ACh release in the hippocampus was comparable in the two tasks. Experiment 2 tested the possibility that the hippocampus was engaged and participated in learning the response task, as well as the place task, because of the availability of extra-maze cues. Rats were trained on a response version of a maze under either cue-rich or cue-poor conditions. The findings indicate that ACh release in the hippocampus increased similarly under both cue conditions, but declined during training on the cue-poor condition, when spatial processing by the hippocampus would not be suitable for solving the maze. In addition, high baseline levels of ACh release in the hippocampus predicted rapid learning in the cue-rich condition and slow learning in the cue-poor condition. These findings suggest that ACh release in the hippocampus augments response learning when extra-maze cues can be used to solve the maze but impairs response learning when extra-maze cues are not available for use in solving the maze. 相似文献
998.
Transient hippocampal down-regulation of Kv1.1 subunit mRNA during associative learning in rats 下载免费PDF全文
Kourrich S Manrique C Salin P Mourre C 《Learning & memory (Cold Spring Harbor, N.Y.)》2005,12(5):511-519
Voltage-gated potassium channels (Kv) are critically involved in learning and memory processes. It is not known, however, whether the expression of the Kv1.1 subunit, constituting Kv1 channels, can be specifically regulated in brain areas important for learning and memory processing. Radioactive in situ hybridization was used to evaluate the content of Kv1.1 α-subunit mRNA in the olfactory bulb, ventral, and dorsal hippocampus at different stages of an odor-discrimination associative task in rats. Naive, conditioned, and pseudoconditioned animals were sacrificed at different times either prior to a two-odor significance learning or after odor discrimination was established. Important decreases of Kv1.1 mRNA levels were transiently observed in the ventral hippocampus before successful learning when compared with the pseudoconditioned group. Moreover, temporal group analysis showed significant labeling alterations in the hippocampus of conditioned and pseudoconditioned groups throughout the training. Finally, Kv1.1 mRNA levels in the hippocampus were positively correlated with odor-reward association learning in rats that were beginning to discriminate between odors. These findings indicate that the Kv1.1 subunit is transiently down-regulated in the early stages of learning and suggest that Kv1 channel expression regulation is critical for the modification of neuronal substrates underlying new information acquisition. 相似文献
999.
The study reported here examined whether size perception based on monocular distance cues is computed automatically. Participants
were presented with a picture containing distance cues, which was superimposed with a pair of digits differing in numerical
value. One digit was presented so as to be perceived as closer than the other. The digits were of similar physical size but
differed in their perceptual size. The participants’ task was to decide which digit was numerically larger. It was found that
the decision took longer and resulted in more errors when the perceptual size of the numerically larger digit was smaller
than the perceptual size of the numerically smaller digit. These results show that perceived size affects performance in a
task that does not require size or distance computation. Hence, for the first time, there is empirical support for the working
assumption of the visual perception approach that size perception based on monocular distance cues is computed automatically. 相似文献
1000.
In visual perception, part segmentation of an object is considered to be guided by image-based properties, such as occurrences
of deep concavities in the outer contour. However, object-based properties can also provide information regarding segmentation.
In this study, outer contours and interpretations of object configurations were manipulated to examine differences between
image-based and object-based segmentation in a visual search task. We found that locating a two-dimensional object configuration
with deep concavities in the outer contour depends on the type of outer contour of the surrounding distractors. In addition,
locating a three-dimensional object configuration was harder when it was surrounded by object-based-disconnected distractors,
as compared with object-based-connected distractors, regardless of image-based connections in these distractors. We conclude
that segmentation based on the outer contours of a target facilitates its localization. However, when three-dimensional information
is available, segmentation strongly depends on object-based properties, rather than on image-based properties. 相似文献