Single-trial EEG-fMRI reveals the dynamics of cognitive function

Two major non-invasive techniques in cognitive neuroscience, electroencephalography (EEG) and functional magnetic resonance imaging (fMRI), have complementary advantages with regard to their spatial and temporal resolution. Recent hardware and software developments have made it feasible to acquire EEG and fMRI data simultaneously. We emphasize the potential of simultaneous EEG and fMRI recordings to pursue new strategies in cognitive neuroimaging. Specifically, we propose that, by exploiting the combined spatiotemporal resolution of the methods, the integration of EEG and fMRI recordings on a single-trial level enables the rich temporal dynamics of information processing to be characterized within spatially well-defined neural networks.     

Enabling a man with multiple disabilities and limited motor behavior to perform a functional task with help of microswitch technology

This study evaluated the extent to which two microswitches used as interfaces would enable a man with multiple disabilities and limited motor behavior to operate an electric door opener at the entrance of the day center that he attended. Analysis showed the man (a) learned to use the two microswitches, (b) preferred the microswitch placed at his wheelchair's footrest (which also allowed more effective responding) over the microswitch placed at his wheelchair's armrest, and (c) maintained his positive performance at the 1- and 2-mo. postintervention checks. The results were discussed from a technical and practical standpoint and in terms of implications for the quality of life of persons with disabilities.     

Self-regulation and personality: how interventions increase regulatory success, and how depletion moderates the effects of traits on behavior

Self-regulation is a highly adaptive, distinctively human trait that enables people to override and alter their responses, including changing themselves so as to live up to social and other standards. Recent evidence indicates that self-regulation often consumes a limited resource, akin to energy or strength, thereby creating a temporary state of ego depletion. This article summarizes recent evidence indicating that regular exercises in self-regulation can produce broad improvements in self-regulation (like strengthening a muscle), making people less vulnerable to ego depletion. Furthermore, it shows that ego depletion moderates the effects of many traits on behavior, particularly such that wide differences in socially disapproved motivations produce greater differences in behavior when ego depletion weakens the customary inner restraints.     

Influence of postural regulation in male judokas' direction of falls: comment on Paillard, et al. (2005)

The survey of Paillard pinpoints three important areas of reflection: what new knowledge is added, what are the internal perspectives, and what are the external perspectives.     

Smoking involvement during adolescence among African Americans and Puerto Ricans: risks to psychological and physical well-being in young adulthood

The major aim of this study was to examine the longitudinal association between adolescent smoking involvement and self-reported psychological and physical outcomes in young adulthood. Participants included 333 African Americans and 329 Puerto Ricans who were surveyed in 1990 in their New York City schools and interviewed in 1995 and 2000-2001, primarily in their homes. The psychological outcomes included ego integration, symptoms of depression, anxiety, and interpersonal difficulty. The physical health measures included a general health rating, number of illnesses, and symptoms of ill health. Also, three scales measured problems due to alcohol, marijuana, and other illicit drug use. Smoking involvement varied by age, sex, and ethnicity but not by socioeconomic status nor by late adolescent parental status. Analysis showed that the relationships between adolescent smoking involvement and psychological and physical health problems in young adulthood remained significant even with control on demographic factors, earlier levels of the outcome variables, and marijuana use. The relationships between smoking behavior and problems with alcohol, marijuana and other illicit drug use were particularly strong. Thus, adolescent smoking seems to have a wide range of clinical implications for young adulthood.     

The distinction between positive and negative reinforcement: use with care

It is customary in behavior analysis to distinguish between positive and negative reinforcement in terms of whether the reinforcing event involves onset or offset of a stimulus. In a previous article (Baron & Galizio, 2005), we concluded that a distinction of these terms is not only ambiguous but has little if any functional significance. Here, we respond to commentaries by a group of distinguished behavior analysts about the issues we raised. Although several of the commentators argued for preservation of the distinction, we remain unconvinced that its benefits outweigh its weaknesses. Because this distinction is so deeply embedded in the language of behavior analysis, we hardly expect that it will be abandoned. However, we hope that the terms positive and negative reinforcement will be used with circumspection and with full knowledge of the confusion they can engender.     

Anxiolytic-like activity of SB-205384 in the elevated plus-maze test in mice

Recent studies point to a major role for alpha2-containing GABA-A receptors in modulating anxiety. However, the possible implication of GABA-A receptors containing the alpha3 subunit on anxiety is less known. The aim of this study was to examine the effects of SB-205384 (0.5-4 mg/kg, i.p.), an alpha3 subunit positive modulator of GABA-A receptor, on anxiety tested in the elevated plus-maze in male mice, using classical and ethological parameters. Mice treated with SB-205384 showed an increase in the frequency of entries and the time spent in open arms, as well as a reduction in the time spent in closed arms, as compared with the control group. A notable increase of "head-dipping" unprotected and a reduction of "stretched-attend posture" protected was also evident. These findings indicate that SB-205384 exhibits an anxiolytic-like profile in the elevated plus-maze test, suggesting that GABA-A receptors which contain the alpha3 subunit might be involved in regulation of anxiety.