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Two experiments are reported which investigated how subject gender and time-of-day influenced the estimation of duration and the perception of task-related mental workload. In the first experiment, 24 subjects performed a filled time-estimation task in a constant blacked-out, noise-reduced environment at 0800h, 1200h, 1600h, and 2000h, respectively. In the second experiment, 12 different subjects performed an unfilled time estimation task in similar conditions at 0900h, 1400h, and 1900h. At the termination of all experimental sessions, participants completed the NASA Task Load Index workload assessment questionnaire as a measure of perceived mental workload. Results indicated that physiological response, reflected in body temperature change, followed an expected pattern of sequential increase with time-of-day. However, estimates of duration and the perception of mental workload showed no significant effects for time-of-day. In each of the experiments there were significant differences in time estimation and mental workload response contingent on the gender of the participant. These results are interpreted in light of the previous positive findings for circadian fluctuation in performance efficiency and the equivocal findings of a gender difference in time estimation. A unifying account of these collective results is given based on gender by time-of-day interactional effects. An earlier version of this paper was presented at the 32nd Annual Meeting of the Human Factors Society, Anaheim, CA, October, 1988.  相似文献   
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[The author identifies] five problems familiar to clinical ethicists. (1) Physicians often do not recognize important ethical issues. (2) Debate exists over whether such consultations should give specific management recommendations. (3) Principles of medical ethics cannot, by themselves, resolve real ethical issues. (4) The patient's interests sometimes conflict with the interests of the family, the health professionals, and the hospital. (5) Clinical ethics consultations take a toll on the consultant....[He] discuss[es] the implications of each problem for clinical ethics consultations and offer[s] a solution to it.  相似文献   
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The shortening of the QT interval of the electrocardiogram coincident with acceleration of heart rate and vice versa has been accepted for many years as evidence that the action potential duration and hence QT are necessarily dependent on heart rate. Exceptions to this rule have been attributed to the intervention of counteracting autonomic effects. In order to test this assumption, 26 conscious dogs divided into three groups were tested during baroreceptor stimulation by a bolus injection of phenylephrine. Seventeen dogs had been used in earlier studies in which they had undergone an experimental anterior myocardial infarction with apparent full recovery. A group of those dogs underwent beta-adrenergic blockade by intravenous atenolol 30 min prior to the baroreceptor activation. To test the intactness of the baroreceptor responses in the previously infarcted dogs, a third group of nine dogs that had had no prior myocardial infarction was included. All dogs were adapted to the laboratory environment and were not sedated during experiments. Simultaneous recordings of RR, QT interval, and phasic arterial pressure were made in all dogs before and during baroreceptor stimulation. In the normal group, and the previously infarcted group that received no atenolol, baroreceptor stimulation elicited a small (8/msec), but significant prolongation of the QT associated with a nearly 50% reduction in heart rate. The QT interval of the atenolol-treated dogs, although significantly more prolonged before stimulation, remained unchanged during the reflex. The data indicate that withdrawal of ventricular sympathetic tone may prolong the QT interval, thereby confirming the role of sympathetic innervation in the control of QT.(ABSTRACT TRUNCATED AT 250 WORDS)  相似文献   
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