An analysis of some sensitizing agents in the pathogenesis of stress-induced gastric erosive disease

Prior surgical implantation of a venous catheter sensitized rats to coldimmobilization stress. Three of six catheterized females succumbed during the stress. The remaining rats fell into two groups in terms of their core temperature at the end of the stress period: Male uncatheterized rats had higher temperatures than rats in the other three groups. No relation was found between catheter patency and magnitude of hypothermia. Degree of gastric disease paralleled the core temperature findings in that the male uncatheterized rats had significantly fewer gastric erosions than the rats in the other three groups. Additionally, a robust effect of gender was found with uncatheterized females showing more hypothermia and more gastric disease than uncatheterized males. A subsequent experiment was conducted to evaluate whether anesthesia or wearing the protective spring was responsible in part for the sensitization seen. Here, the gender difference was less although females consistently averaged lower core temperatures after stress than did males. Despite similar core temperatures after stress, females that were prepared with the protective spring apparatus developed more gastric disease than female controls or similarly treated males. Thus, the additional sensitization exhibited by females in the first experiment may relate to the fact that both catheterization and the taping procedure were sensitizers while only catheterization was a sensitizer for males.     

Postnatal development of respiratory and vocal responses during aversive classical conditioning in cats

Respiratory rate, respiration amplitude, and vocal responses were recorded in cats of different ages during classic conditioning. Vocal responses to the conditional stimulus (CS) appeared first in 8-week-old kittens, and became prominent at older ages. An increase in respiration rate occurred after the onset of the CS in cats of all ages. Similarly, the decrease of respiration amplitude was observed at all ages, but only in 8-week-old and older subjects did this response resemble an adult pattern. In 4-week-old kittens the response was characterized by an early and brief peak, suggesting an alpha conditional response (CR). Clear and significant discrimination between a warning and a safety signal was present in both respiratory and vocal responses after the age of 8 weeks.     

Tonal frequency shifts and gaps in acoustic stimulation as reflex-modifying events

When a relatively weak signal, such as a mild tone, precedes an intense reflex-eliciting stimulus by an appropriate interval (about 100 msec), the amplitude of the elicited reaction is often reduced. It was found that in student volunteers a brief gap in a steady pure tone that occurred 150 msec prior to a mild tap to the glabella (the flat region between the eyebrows) could inhibit the eyeblink elicited by the tap. It was also found that a shift in tonal frequency across a gap in a tone was more inhibitory than a gap with no frequency shift, but it was no more inhibitory than the onset of the short second tone alone. The final study determined the minimum amount of frequency shift required to produce an additional inhibitory effect above that of a gap alone. The findings are discussed in terms of various aspects of sensory processing.     

On the analyst's neutrality

It is by the application of the principle of neutrality, born of his respect for the essential otherness of the patient, that the analyst focuses the dyadic analytic work in the service of the patient's growing self-analytic capacity. Thus, the general principle of neutrality is distinguished from the technical tactic of abstinence, the latter being a specific function utilized to facilitate and foster analytic regression. Neutrality can be defined as it applies to the major subfunctions of the analyst's work ego. Perception of the patient's intrapsychic processes (both empathically and cognitively) requires a neutrality of appearance on the analyst's part in order to minimize the distortion of the unfolding transference neurosis. Integration and understanding of the patient's communications require mastery and neutralization of the analyst's own internal processes in order to minimize countertransferential distortions. Appropriate interpretive intervention requires neutrality of action, i.e., mastery of impulses related to power, neutralizing them into the service of the analytic work; tact is defined as a specific psychoanalytic function in this regard. Collaborative ignorance is examined as a specific instance of false neutrality. In this an analytic guise serves to mask a countertransferential conflict. Neutrality serves as an overriding technical principle, not an imperative for perfectionism . Factors intrinsic to the analytic process also influence the application of this principle.     

The Wundt Myths

Three myths about Wundt have been perpetuated in English language accounts of his work. First, he is said to have founded a Psychologisches Institut (a formally recognized psychological research laboratory) in 1879. Second, he is said to be the first psychologist, as distinct from the first contributor to psychology. Third, he is said to have formulated an elementarist psychology of mental content or experience. The first and second are trivial myths which in isolation would be scarcely worth a comment. The third is a gross misrepresentation which ignores the purposivist-voluntarist underlay of his experimental cognitive psychology and the humanistic, cultural concern of his Völkerpsychofogie.     

Another look at the effects of the system of multicultural pluralistic assessment

The purpose of this study was (a) to determine if a declassification occurs when estimated learning potential (ELP) is used in reevaluation of special education students and (b) to assess the effects of the use of ELP by multidisciplinary teams. Subjects included 107 black and 13 white students (83 males and 37 females) referred for reevaluation from classes for the mentally retarded. Data analysis consisted of determining the percentage of students who would be classified as mentally retarded according to the main criterion of (a) Wechsler Intelligence Scale for Children-Revised (WISC-R) scores, or (b) ELP scores, or (c) multidisciplinary teams' placement. A chi-square test of independence indicated a significant difference between WISC-R and ELP scores; and between multidisciplinary teams' placement and ELP scores (p<.05). Students already in special education classes for the mentally retarded were not determined to be ineligible for services by multidisciplinary teams, even though 15% of the students would be ineligible for services according to ELP scores.     

A temporal limit on the effect of future food on current performance in an analogue of foraging and welfare

Rats obtained access to food twice each 24-hour period. The first session was a work session in which food was available on a progressive-ratio schedule. During the second session, which occurred between 1 and 23 hours after the work session, food was freely available up to a fixed total intake each 24 hours. The situation resembled elements of several real world circumstances, including the choice between continuing to forage in a rapidly depleting patch and waiting for a better patch, and between working now and receiving a guaranteed income later. The purpose of the experiment was to explore the time period over which future access to reward could affect current responding. Contrary to what might be expected from recent theorizing, anticipation of future food delayed by an hour or more after the start of the work session had no effect on current performance. Food intake was high and constant during work sessions except for a prefeeding effect that occurred when the free session closely preceded the next day's work session. Also, an increase in the difficulty of the work schedule increased the amount of work and the maximum price paid for food as if the work session were the only time food was available. The results indicate the importance of considering temporal limits in theories that require animals to integrate input over time to determine the allocation of resources among alternatives.