Clinical trial of contemnol tablets (lithium retard Spofa)

A report on the clinical testing of the lithium-retard medicament Contemnol (Spofa). It details the way lithium-retard treatment is objectively and subjectively superior to the earlier and still current general lithium treatment.     

Status of perfusion scintigraphy in the diagnostic strategy in cerebrovascular disorders and space-occupying lesions

The results of an evaluation of the perfusion scintigraphy findings of 350 hospitalised neurological patients and 55 more strictly selected neurosurgical patients with cerebrovascular complaints, revealed an accuraty of 83%, a sensitivity of 89%, and a specificity of 83%. The selection of the patients had no influence on the results as a whole. Compared with contrast-medium angiography, incorrect diagnosis must be expected in 17% of the cases. This includes erroneous negative findings in 10% of the cases. Grounds for misinterpretations are suggested, and the biological and methodological limitations of the method are set forth.     

Neurochemical knowledge in electroconvulsive therapy (ECT)

The paper is concerned with an attempt to generalize and categorize current hypotheses on the biochemical basis of ECT. The hypotheses are critically evaluated with respect to the relevance of their experimental fundamentals. Thus, certain hypotheses are valid only in a qualified sense. Particular interest is focussed on those conceptions which try to correlate ECT-induced changes in synaptic receptor sensitivities (up-/down-regulation) with super- resp. subsensitivity hypotheses of psychoses. In this connection, noradrenergic and opioid systems on the one hand, and the axis hypothalamus-hypophysis on the other hand seem to play a dominant role.     

Principles of computer-assisted classification in psychiatry

The use of computer based diagnostic decision and artificial intelligence are discussed in relation to the problems of validity and reliability of psychiatric diagnoses. The authors suggest a definition of a computer aided classificator as an existent decision system for an automatically analysis of findings.     

The two-woman phenomenon

A distinct type of phenomenon that has not been previously noted as such is named and described. Men who present a two-woman phenomenon retain a commitment to wife and marriage while loving another woman. Conflict arises only when one of the women has to be relinquished. It is postulated that many men with this pattern of loving have experienced a traumatic childhood and an oedipal conflict which defensively involved two maternal objects in fantasy or reality. One mother was hated, the other loved. This dynamic is one possible determinant leading to the two-woman phenomenon.     

Psychometric detection of depressive mood conditions

An investigation into the diagnostic value of psychometric methods for the diagnosis of depressive states involved five psychometric questionnaires, one concentration test procedure, and one problem-solving approach to register cognitive processes. The data obtained for 80 depressive patients of varied aetiology were compared with those of sample of 80 neurotics without depressive aberration. Even univariate comparisons revealed statistically significant differences between the two samples. Multivariate methods (factor analysis, discriminative analysis) yielded more differentiated information. The "Scale for depression depth measurements" was found to be of particular diagnostic relevance; it was standardized for the time being.     

Personality and social resources in immediate and continued stress resistance among women

In this study we investigated the immediate and continued impact on women of a major stressful event, the outcome of pregnancy, and the mitigating effect of self-esteem and intimacy with their spouse on their reactions. Few other studies have investigated initial reactions to crisis events. Ninety-nine Israeli women who experienced either normal delivery or pregnancy complications were interviewed at the time of the event and 3 months later. High self-esteem was found to limit feelings of depression at both times. Intimacy with spouse limited depression at the event, but not at follow-up. High self-esteem was seen as always being exploitable by women who possessed it, whereas the benefit of intimacy with spouse was seen as being dependent on situational demands and environmental constraints. Cross-cultural implications were presented.     

Recipient's mood, relationship type, and helping

We conducted two studies to examine how a potential helper is affected by having a communal orientation toward a relationship with a potential recipient and by the potential recipient's sadness. We hypothesized that (a) having a communal orientation would increase helping and that (b) people high in communal orientation, but not others, would respond to a potential recipient's sadness by increasing helping. These hypotheses were tested in two studies. In Study 1, individual differences in communal orientation toward relationships were measured by using a new communal orientation scale reported for the first time in this article. In Study 2, manipulations were used to lead subjects to desire either a communal or an exchange relationship with another person. In both studies, subjects were exposed to a sad person or to a person in a neutral mood whom they were given a chance to help. As hypothesized, in both studies communally oriented subjects helped the other significantly more than did others. Also as hypothesized, in both studies communally oriented subjects but not others, increased helping in response to the other person's sadness although this effect reached statistical significance only in the second study.