RSCORE-J: Pooled rating-method data: A computer program for analyzing pooled ROC curves

RSCORE-J, a computer program for a signal-detection analysis of pooled rating-method data, is listed and described. RSCORE-J computes jackknife estimates of ROC parameters and their standard errors from rating-method data pooled over a group of observers.     

Monocular-contingent and binocular-contingent aftereffects

Alternate monocular and binocular exposure to complementary stimulation can yield opposite but coexisting aftereffects that are contingent on whether the test display is viewed with one eye or two eyes. The motion aftereffect was studied by adapting each eye separately to a contracting spiral and both eyes together to an expanding spiral. The stationary test spiral subsequently appeared to be expanding when viewed monocularly, but to be contracting when it was seen with both eyes open. With respect to the McCollough effect, after monocular exposure to red-vertical and green-horizontal gratings and binocular exposure to red-horizontal and green-vertical gratings, the appearance of the color of the test gratings when viewed with one eye was different from that when viewed with both eyes. Opposite, coexisting aftereffects induced by complementary stimulation can be interpreted as evidence that there are unique binocular aspects to visual function.     

Concepts underlying the development of modules

The need for common pedagogical and design features in courseware is discussed. A particularly useful feature would allow use of courseware in either of two “modes”: as an “electronic chalkboard” for the instructor who wishes to take advantage of the computer in a traditional lecture setting, or as an “electronic study guide” in which students interact individually with the programs. Development of programs using these two modes can be facilitated using Author-Assist, a set of routines and a program skeleton being developed by CONDUIT (1983). Author-Assist provides procedures for use of several types of automatic menu generation, automatic text formatting in “text ports,” mixed text and graphics, protected input routines, lowercase characters in text, automatic scaling of graphic displays using “graphports,” on-screen calculator functions, and a variety of other features.     

The University Of Colorado Meaning Norms

There exist surprisingly few normative lists of word meanings even though homographs—words having single spellings but two or more distinct meanings—are useful in studying memory and language. The meaning norms that are available all have one or more weaknesses, including: (1) the collection of free associates rather than meanings as responses to the stimulus words; (2) the collection of single rather than multiple responses to the stimulus words; (3) the inclusion of only the two most frequently occurring meaning categories, rather than all meaning categories, for the stimulus words; (4) omission of the responses typical of each meaning category; (5) inadequate randomization of the presentation order of the stimulus words; and (6) unpaced presentation of the stimulus words. We have compiled meaning norms for 90 common English words of low, medium, and high concreteness using a methodology designed to correct these weaknesses. Analysis showed that words of medium concreteness have significantly more first-response meanings than do words of either low or high concreteness, lending support to the view that concreteness is a categorical, rather than a continuous, semantic attribute.     

Impact of Institutional Review Boards on cancer research

The concepts of informed consent and surveillance of human research designed to protect human subjects is commendable. The regulations of the Institutional Review Board (IRB) are having a major impact on clinical cancer research. There is greater administrative time needed of the investigator, the mechanisms of patient care have become cumbersome and some patients reject optional medical management that could be life saving. IRB regulations must be flexible to meet the needs of human subjects as well as those of the clinical investigator.     

An analysis of some sensitizing agents in the pathogenesis of stress-induced gastric erosive disease

Prior surgical implantation of a venous catheter sensitized rats to coldimmobilization stress. Three of six catheterized females succumbed during the stress. The remaining rats fell into two groups in terms of their core temperature at the end of the stress period: Male uncatheterized rats had higher temperatures than rats in the other three groups. No relation was found between catheter patency and magnitude of hypothermia. Degree of gastric disease paralleled the core temperature findings in that the male uncatheterized rats had significantly fewer gastric erosions than the rats in the other three groups. Additionally, a robust effect of gender was found with uncatheterized females showing more hypothermia and more gastric disease than uncatheterized males. A subsequent experiment was conducted to evaluate whether anesthesia or wearing the protective spring was responsible in part for the sensitization seen. Here, the gender difference was less although females consistently averaged lower core temperatures after stress than did males. Despite similar core temperatures after stress, females that were prepared with the protective spring apparatus developed more gastric disease than female controls or similarly treated males. Thus, the additional sensitization exhibited by females in the first experiment may relate to the fact that both catheterization and the taping procedure were sensitizers while only catheterization was a sensitizer for males.     

Postnatal development of respiratory and vocal responses during aversive classical conditioning in cats

Respiratory rate, respiration amplitude, and vocal responses were recorded in cats of different ages during classic conditioning. Vocal responses to the conditional stimulus (CS) appeared first in 8-week-old kittens, and became prominent at older ages. An increase in respiration rate occurred after the onset of the CS in cats of all ages. Similarly, the decrease of respiration amplitude was observed at all ages, but only in 8-week-old and older subjects did this response resemble an adult pattern. In 4-week-old kittens the response was characterized by an early and brief peak, suggesting an alpha conditional response (CR). Clear and significant discrimination between a warning and a safety signal was present in both respiratory and vocal responses after the age of 8 weeks.     

Frames of reference in preschoolers’ perception of motion

Experiments 1 and 2 established children’s (mean age 3 years, 7 months) subject-relative and object-relative motion thresholds at 1°31.37′/sec and 1°9.33′/sec, respectively, speeds well above those found for adults. Experiment 3 established that preschoolers, like adults, attribute object-relative motion to the smaller of two objects, with the inducing properties of the larger stimulus greatest when it is surrounding rather than adjacent to a smaller stimulus. The inducing advantage of surroundedness was equivalent for a single-element square frame and a multielement six-dot frame.     

Prenatal maternal stress: Differential effects upon male and female offspring responses to restraint stress as adults

Pregnant primiparous rats were subjected to four days of light restraint stress on postconception days 7 through 10, inclusive, coincident with the development of the fetal gastrointestinal system. Twenty male and twenty female offspring from prenatally stressed and nonstressed rats were then subjected to two hours of supine cold-restraint as adults. Eighty percent of nonprenatally stressed offspring developed gastric lesions, while 47.5% of offspring of prenatally stressed mothers displayed lesions. A significant sex-stress interaction was detected, indicating that male offspring from prenatally stressed mothers display less severe gastric lesions in response to restraint stress as adults than do male offspring from nonprenatally stressed mothers. Female offspring from both prenatal stress conditions showed similar levels of stress-induced lesions.