Information Channels and Biomarkers of Disease

Current research in molecular epidemiology uses biomarkers to model the different disease phases from environmental exposure, to early clinical changes, to development of disease. The hope is to get a better understanding of the causal impact of a number of pollutants and chemicals on several diseases, including cancer and allergies. In a recent paper Russo and Williamson (Med Stud, 2012) address the question of what evidential elements enter the conceptualisation and modelling stages of this type of biomarkers research. Recent research in causality has examined Ned Hall’s distinction between two concepts of causality: production and dependence (Hall in Causation and counterfactuals. MIT Press, Cambridge, pp 225–276, 2004). In another recent paper, Illari (Philos Technol, p 20, 2011b) examined the relatively under-explored production approach to causality, arguing that at least one job of an account of causal production is to illuminate our inferential practices concerning causal linking. Illari argued that an informational account solves existing problems with traditional accounts. This paper follows up this previous work by investigating the nature of the causal links established in biomarkers research. We argue that traditional accounts of productive causality are unable to provide a sensible account of the nature of the causal link in biomarkers research, while an informational account is very promising.     

Interpreting Causality in the Health Sciences

We argue that the health sciences make causal claims on the basis of evidence both of physical mechanisms, and of probabilistic dependencies. Consequently, an analysis of causality solely in terms of physical mechanisms or solely in terms of probabilistic relationships, does not do justice to the causal claims of these sciences. Yet there seems to be a single relation of cause in these sciences—pluralism about causality will not do either. Instead, we maintain, the health sciences require a theory of causality that unifies its mechanistic and probabilistic aspects. We argue that the epistemic theory of causality provides the required unification.     

The picture superiority effect in recognition memory: A developmental study using the response signal procedure

Items studied as pictures are better remembered than items studied as words even when test items are presented as words. The present study examined the development of this picture superiority effect in recognition memory. Four groups ranging in age from 7 to 20 years participated. They studied words and pictures, with test stimuli always presented as words, and time to respond to test stimuli was manipulated. The picture superiority effect showed a clear developmental trend. In the condition in which participants had ample response time, a significant picture superiority effect appeared in all but the youngest group. With short response time, a significant picture superiority effect appeared only among 11- and 20-year-old groups, while a significant reverse of the picture superiority effect was detected in the youngest group. These results were interpreted as suggesting that different memory processes (familiarity and recollection) contribute differently to the picture superiority effect at different stages of development.     

Understanding the effect of a numerical anchor

Wegener et al. extended the investigation of the anchoring phenomenon to include the manipulation of cognitive load and several traditional factors in persuasion such as source credibility. To this breadth strategy might be added approaches that focus more on depth. By depth is meant an understanding of the underlying mechanisms of anchoring and the forces driving those mechanisms.     

How persuasive messages can influence behavior without awareness

A persuasive message that favors one option in a binary choice can enhance the apparent value of its target by biasing the interpretation of subsequent information. The message installs its target as the initial leader in preference and lets the predecisional distortion of information defend that leadership position. An experiment that contrasts showing TV commercials before and after objective product information demonstrates this process. Ratings of the importance of the commercials to the choice indicate that people are aware of advertising's direct effect on their choice but not of its indirect effect through the biased evaluation of the product information.