Bartter综合征的研究进展

Bartter综合征（BS）是一种内分泌与肾脏功能紊乱的遗传代谢性疾病,分子遗传学表明为离子通道基因突变所致,各年龄段均可发病,主要见于儿童时期,临床罕见。因为许多临床医师对本痛缺乏认识而易延误诊治。若能及时治疗,可较好地控制病情,改善患儿生活质量,减少后遗症的发生率和病死率。近年来,BS的发病率有逐渐上升趋势。因此,本文对BS的发病机制、临床表现、诊断与治疗的研究现状做一总结,旨在提高临床医师对本病的认识,争取做到早诊断早治疗,改善患儿预后。     

婴儿面孔种族效应的发展：经验的作用

面孔种族效应是指个体对本族面孔与他族面孔的加工存在差异,即对本族面孔的识别比他族面孔更快速、更准确,而对他族面孔的分类则优于本族面孔。经验是否以及如何影响面孔种族效应的发展,一直是研究者关注的焦点。近十几年,越来越多的学者对婴儿面孔种族效应进行了研究,已有成果主要涉及两个方面：（1）自然条件下婴儿面孔种族效应的出现与发展,即婴儿在面孔种族偏好、识别与分类以及面孔种族加工方式上的变化;（2）训练对婴儿面孔种族效应的影响。未来应丰富研究模式,增强实验材料的生态性,联合新的神经生理技术手段,进一步揭示婴儿经验对面孔种族效应的作用机制。     

A moderated mediation model of e-mentoring

Based on a longitudinal sample of 1381, this study develops and tests a moderated mediation model of electronic mentoring (e-mentoring). Results show evidence that frequency of interaction between protégés and mentors mediates the relationships between program antecedents (the protégé’s previous internet experience and initial motivation to participate) and program outcomes of general self-efficacy and task-efficacy. In addition, the protégé’s general self-efficacy prior to starting the program was found to moderate the relationships between protégé and mentor interaction frequency and program outcomes of task and general self-efficacy. Unexpectedly, having mentors in the past was not significantly related to program outcomes. Practical implications and future areas of research are identified and discussed.     

Saccades elicit obligatory allocation of visual working memory

In daily life, visual working memory (VWM) typically works in contexts in which people make frequent saccades. Here, we investigated whether people can effectively control the allocation of VWM when making a saccade. Subjects were required to make an intervening saccade in the process of a memory task. The saccade target was either a to-be-remembered item or an extra, not-to-be-remembered item. The results showed that memory performance was poorer when a saccade was made to the extra, not-to-be-remembered item, regardless of its similarity to the memory item(s). In contrast, when memorizing the items while remaining fixated, subjects had similar memory performance whether an extra, not-to-be-remembered item was present or not. Taken together, these results demonstrated that volitional control over VWM allocation is greatly impaired when a saccade is made, indicating that VWM contains an automatic part that cooperates with eye movements and is allocated to a saccade target obligatorily.     

无决策成分的靶记忆与源记忆的加工深度比较

本研究通过两个实验来比较源记忆和靶记忆的难度。实验一比较两种记忆提取阶段的事件相关电位（ERPs）。实验二设置较高的成功标准,比较两者达标所需的时间,以此比较它们的难度。在实验一中,被试先进行项目记忆任务,接着进行源记忆任务（从两位虚拟人处接收项目,并记住项目的来源）和靶记忆任务（向两位虚拟人递送项目,并记住项目的去向）。源记忆和靶记忆的测试阶段要求被试再认项目的源或靶,并记录提取阶段的脑电。结果显示,虽然源记忆与靶记忆的正确率没有显著差异,但是在正确提取的ERP中观察到,两者与回想有关的LPC之间有边缘显著差异（靶记忆比源记忆更趋正向,且在顶区差异最明显）,这说明在回想上,靶记忆可能比源记忆需要更深的加工。实验二将源记忆和靶记忆结合在同一个任务中,要求被试反复尝试,直至两种记忆的正确率都达到较高的成功标准（近90%）。结果进一步证实,源记忆的加工水平深于源记忆。     

多维数据的视觉呈现技术:elastic模型简介

本文介绍了一种将多维数据视觉化呈现的技术elastic模型．以及以该模型为理论基础开发的软件ViDaExpert。elastic模型与ViDaExpert使用便捷功能强大．可以帮助解决多维数据视觉呈现及数据分析问题。     

How social network heterogeneity facilitates lexical access and lexical prediction

People learn language from their social environment. As individuals differ in their social networks, they might be exposed to input with different lexical distributions, and these might influence their linguistic representations and lexical choices. In this article we test the relation between linguistic performance and 3 social network properties that should influence input variability, namely, network size, network heterogeneity, and network density. In particular, we examine how these social network properties influence lexical prediction, lexical access, and lexical use. To do so, in Study 1, participants predicted how people of different ages would name pictures, and in Study 2 participants named the pictures themselves. In both studies, we examined how participants’ social network properties related to their performance. In Study 3, we ran simulations on norms we collected to see how age variability in one’s network influences the distribution of different names in the input. In all studies, network age heterogeneity influenced performance leading to better prediction, faster response times for difficult-to-name items, and less entropy in input distribution. These results suggest that individual differences in social network properties can influence linguistic behavior. Specifically, they show that having a more heterogeneous network is associated with better performance. These results also show that the same factors influence lexical prediction and lexical production, suggesting the two might be related.     

现代福建基督教的历史总结 (1949-1964)

本文从历史学的角度,根据政府档案材料,对新中国建立至“文革”前夕福建基督教历史的基本内容作了客观、扼要的分析总结。总结力求突出这一时期福建基督教的特点。文章最后就这一历史时期福建基督教几大数字变化的原因,对马克思主义关于宗教的根源不在天上、而在人间的科学论断作了相关的理论探讨。     

学校不同群体的阅读信念对记叙文意义建构的影响

采用问卷调查的方法,考察学校三类群体(初中生、大学生、教师)的阅读信念(reading belief)对记叙文意义建构的影响。结果发现:(1)学校三类群体对记叙文的意义建构不同:在表层信息上,教师和大学生显著优于初中生,教师和大学生之间水平相当;而在整体理解上,教师显著优于大学生和初中生,而且大学生也显著优于初中生;(2)在初中阶段,传递信念对记叙文意义建构起主导作用;(3)在大学阶段,互动信念对记叙文意义建构起主导作用。     

Detection of Test Speededness Using Change-Point Analysis

Change-point analysis (CPA) is a well-established statistical method to detect abrupt changes, if any, in a sequence of data. In this paper, we propose a procedure based on CPA to detect test speededness. This procedure is not only able to classify examinees into speeded and non-speeded groups, but also identify the point at which an examinee starts to speed. Identification of the change point can be very useful. First, it informs decision makers of the appropriate length of a test. Second, by removing the speeded responses, instead of the entire response sequence of an examinee suspected of speededness, ability estimation can be improved. Simulation studies show that this procedure is efficient in detecting both speeded examinees and the speeding point. Ability estimation is dramatically improved by removing speeded responses identified by our procedure. The procedure is then applied to a real dataset for illustration purpose.