顿悟与问题表征的转变

阐述了解决残缺棋盘问题的顿悟过程。该实验的结果证明,顿悟过程中需要发现一种正确的问题表征,即对等性问题空间,为了发现这一表征,被试必须使问题表征从“铺试问题空间”转变为“元水平的问题空间”．被试在这两个空间中进行搜索时,必须有很强的限制,使搜索成为有高度选择性的搜索,才能最终在元水平问题空间中发现正确的表征。本研究还发现,被试的搜索并不总是知觉驱动的,有时是概念驱动的,而且后者的迁移性更高。     

加压素对记忆巩固过程作用的研究 Ⅱ.GABA在加压素易化记忆巩固过程中作用的探讨

本文探讨了脑内GABA能神经元在加压素易化记忆巩固过程中的作用。结果表明,第三天建立实验后立即腹腔注射印防己毒素(picrotoxin,0.5mg/kg),消除了加压素对条件反应消退过程的延缓作用,而注射氨氧乙酸(aminooxy-acetic acid,20mg/kg)获得相反结果。 实验结果提示,脑内GABA能神经元可能参与了加压素对记忆巩固过程的易化作用。     

Psychometric properties of the Cognitive Emotion Regulation Questionnaire: Chinese version

The aim of the present study was to develop a Chinese version of the Cognitive Emotion Regulation Questionnaire (CERQ-C) and to examine its psychometric properties in a sample of Chinese university students. The English version of the Cognitive Emotion Regulation Questionnaire was translated and back-translated prior to its administration to 791 participants recruited from two universities in Changsha, Hunan (China). Internal consistency, test–retest reliability, inter-scale reliability, and factorial validity were analysed. The CERQ-C exhibited: (1) moderate internal consistency (Cronbach's α=.83); (2) a mean inter-class correlation coefficient of .79; (3) a mean inter-item correlation coefficient of .09; and (4) moderate test–retest reliability (.64). Confirmatory factor analyses supported the original CERQ nine-factor model. Finally, with respect to criterion validity, several CERQ-C subscales were uniquely associated with symptoms of depression and anxiety.     

汶川地震8.5年后青少年身心状况研究

汶川地震8.5年后,对地震极重灾区的2291名青少年进行问卷调查,考察其创伤后应激障碍(PTSD)、抑郁、创伤后成长(PTG)和生活满意度等身心反应的现状及其共存形态。结果发现:(1)地震发生8.5年后4.75%的青少年有明显的PTSD症状,29.98%的青少年有明显的抑郁症状,其中女生、少数民族学生、高年级学生的症状水平更高;46.13%的青少年报告其出现了明显的PTG,其中女生和少数民族学生的PTG水平更高;青少年的生活满意度较低,其中初一年级显著高于其他年级,但性别和民族差异不显著;(2)青少年的PTSD与抑郁呈显著正相关、与生活满意度呈显著负相关、与PTG相关不显著,抑郁与PTG和生活满意度呈显著负相关,PTG与生活满意度呈显著正相关;(3)青少年的PTSD、抑郁、PTG和生活满意度之间具有共存的形态,具体表现为成长组(32.6%)、低症状组(39.4%)、症状-成长共存组(5.8%)、中等症状共病组(17.8%)和高度症状共病组(4.4%)等5种类别。     

Coping,social support,stigma, and gender difference among people living with HIV in Guangxi,China

The current study examined whether gender, HIV-related stigma, social support, and the interaction between gender and social support are associated with coping responses among people living with HIV and AIDS (PLWHA) in Guangxi, China. A total of 2987 PLWHA in Guangxi participated from October 2012 to August 2013. Multivariate analysis of covariance was conducted with gender and social support as main factors in the model, and stigma and other variables as covariates. After controlling for demographic variables and stigma, there were significant main effects of emotional social support (F = 1.61, p < .001), functional social support (F = 1.67, p < .001), and informational social support (F = 3.67, p < .001) on various coping strategies. The interaction between gender and informational social support (F = 1.33, p < .05), internalized stigma (F = 37.03, p < .001) and perceived stigma (F = 9.16, p < .001) were associated with various coping strategies. Findings signify the importance of HIV-related stigma and social support differences in the coping strategies among PLWHA in Guangxi, China.     

Older but not younger infants associate own‐race faces with happy music and other‐race faces with sad music

We used a novel intermodal association task to examine whether infants associate own‐ and other‐race faces with music of different emotional valences. Three‐ to 9‐month‐olds saw a series of neutral own‐ or other‐race faces paired with happy or sad musical excerpts. Three‐ to 6‐month‐olds did not show any specific association between face race and music. At 9 months, however, infants looked longer at own‐race faces paired with happy music than at own‐race faces paired with sad music. Nine‐month‐olds also looked longer at other‐race faces paired with sad music than at other‐race faces paired with happy music. These results indicate that infants with nearly exclusive own‐race face experience develop associations between face race and music emotional valence in the first year of life. The potential implications of such associations for developing racial biases in early childhood are discussed.     

Verbal–spatial IQ discrepancies impact brain activation associated with the resolution of cognitive conflict in children and adolescents

Verbal–spatial discrepancies are common in healthy individuals and in those with neurodevelopmental disorders associated with cognitive control deficits including: Autism Spectrum Disorder, Non‐Verbal Learning Disability, Fragile X, 22q11 deletion, and Turner Syndrome. Previous data from healthy individuals suggest that the magnitude of the difference between verbal IQ (VIQ) and performance IQ (PIQ) scores (the VIQ>PIQ discrepancy) is associated with reduced thickness in frontal and parietal cortices (inferior frontal, anterior cingulate, inferior parietal lobule, and supramarginal gyrus) that support cognitive control. Unknown is whether the VIQ>PIQ discrepancy is associated with functional deficits in these areas in healthy or ill children and adolescents. We assessed the effects of the VIQ>PIQ discrepancy on fMRI BOLD response during the resolution of cognitive conflict in 55 healthy children and adolescents during performance of a Simon Spatial Incompatibility task. As the magnitude of the VIQ>PIQ discrepancy increased, activation of fronto‐striatal, limbic, and temporal regions decreased during conflict resolution (p < .05, corrected). In exploratory analyses, the VIQ>PIQ discrepancy was associated with reduced functional connectivity from right inferior frontal gyrus to right thalamus and increased functional connectivity to right supramarginal gyrus (ps < .03, uncorrected). The VIQ>PIQ discrepancy may be an important aspect of an individual's cognitive profile and likely contributes to, or is associated with, deficient cognitive control processes characteristic of many childhood disorders.     

体外循环所致炎性肺损伤机制及保护进展

肺损伤是体外循环心内直视手术的主要并发症之一.肺损伤的机制十分复杂,主要是全身炎性反应和缺血/再灌注损伤所致.肺保护的方法多种多样,其目的是降低全身炎性反应,减轻或避免缺血/再灌注损伤.本文探讨体外循环肺损伤的机制和保护进展.