Plasticity of inhibition in older adults: Retest practice and transfer effects

This study assessed plasticity of inhibition in older adults through examining retest practice effects in a six-session training paradigm using the Stroop task and the training-induced transfer effects to a range of cognitive measures. Fifty-six older adults (aged 60-84 years, mean = 71.05, standard deviation = 6.17) participated in this study. They were evenly assigned to one of four groups: summary feedback, individualized and adaptive feedback, no-feedback, or a no-contact control group. The results suggest that older adults are able to improve inhibition across retest sessions but unable to transfer the retest practice effects to other tasks. In addition, the improvement is not item specific and feedback does not appear to moderate the magnitude of the training benefits; however, feedback does appear to reduce interference variance across retest practice sessions. (PsycINFO Database Record (c) 2012 APA, all rights reserved).     

Retest learning in the absence of item-specific effects: Does it show in the oldest-old?

This study examined whether the nonitem-specific retest learning effects, previously shown with young-old adults primarily in their 60s and 70s, could be extended to oldest-old adults aged 80 and onward. Twenty-one oldest-olds participated in an 8-session retest training program with three ability domains: perceptual speed, inductive reasoning, and visual attention. Their data were compared with the data of 30 young-olds collected in a previous work (Yang, Reed, Russo, & Wilkinson, 2009). The two age groups showed largely equivalent retest learning effects. In addition, only young-olds were able to benefit from item-specific retest learning, specifically in reasoning and perceptual speed tests. (PsycINFO Database Record (c) 2012 APA, all rights reserved).     

Phosphorylated nerve growth factor-induced clone B (NGFI-B) translocates from the nucleus to mitochondria of stressed rat cardiomyocytes and induces apoptosis

Stress induces cardiac dysfunction and cardiomyocyte injury, and while current data indicate that mitochondria play a key role in this process, the mechanisms remain unknown. In this study, we found that in rats, restraint stress induced nerve growth factor-induced clone B (NGFI-B) translocation from the nucleus to mitochondria in cardiomyocytes. This translocation promoted cytochrome c release from mitochondria to the cytoplasm, which ultimately resulted in cardiomyocyte apoptosis. We also found that stress induced oversecretion of glucocorticoids and activated the protein kinase A (PKA) pathway in cardiomyocytes. Enhanced PKA activity increased NGFI-B serine phosphorylation, which caused NGFI-B to translocate from the nucleus to mitochondria. Moreover, a PKA peptide inhibitor blocked NGFI-B serine phosphorylation and translocation. Our data demonstrate that stress affects cardiomyocytes by inducing NGFI-B mitochondrial translocation via serine phosphorylation, which in turn initiates mitochondrial-mediated apoptosis.     

Physiological and psychological impacts on male medical interns during on-call duty

This study aimed to explore the physiological and psychological impacts on male medical interns during on-call duty (OCD). A prospective study of 13 medical interns was carried out using repeated testing during an on-call internal medicine and a duty-free course. There are 10 OCDs per month and each duty is composed of 33.5 consecutive work hours followed by 2 duty-free days for a time period of 3 months. Spectral analysis of R-R intervals was performed to evaluate the participants' heart rate variability. Among the three main spectral components distinguished, a high-frequency (HF) component of 0.15-0.4 Hz and a low-frequency component (LF) of 0.04-0.15 Hz were analyzed. The ratio of LF and HF (LF/HF) was also calculated. Reduced LF/HF, which suggests reduced cardiac sympathetic modulation, was found during duty night work. Increased HF was identified during the first sleep after OCD, which corresponded to the sleepiness scales. The OCD causes temporary emotional influence by the findings of higher anxiety and depression scores. In addition, inattention and impulsiveness, as represented by the continuous performance test score and lower nocturnal sympathetic modulation, were found, which indicated the differences between the internal medicine course and duty-free course. Our study suggests that 10 stressful on-call duties monthly result in reduced sympathetic modulation during duty night work, high anxiety and depression state, and a persistent inattention.     

Unconscious structural knowledge of tonal symmetry: Tang poetry redefines limits of implicit learning

The study aims to help characterize the sort of structures about which people can acquire unconscious knowledge. It is already well established that people can implicitly learn n-grams (chunks) and also repetition patterns. We explore the acquisition of unconscious structural knowledge of symmetry. Chinese Tang poetry uses a specific sort of mirror symmetry, an inversion rule with respect to the tones of characters in successive lines of verse. We show, using artificial poetry to control both n-gram structure and repetition patterns, that people can implicitly learn to discriminate inversions from non-inversions, presenting a challenge to existing models of implicit learning.     

领导权力和地位对下属建言的影响——心理安全感的作用

通过实验研究(研究1、2)和多来源、多时点的实地问卷调查(研究3), 本文发现: 领导权力对下属建言有消极作用, 领导地位对下属建言有积极作用; 领导地位调节领导权力对下属建言的影响, 当领导地位较低时, 领导权力对下属建言的负面作用增强, 反之则不显著; 领导地位对权力的调节作用通过下属心理安全感传递至下属建言行为。这一研究结果有助于阐明组织层级差异(如权力、地位)是如何影响下属建言行为的。     

老年人医疗语篇理解的影响因素和补偿模型

医疗语篇理解是老年人实现自我照护的关键因素,改善老年人医疗语篇理解有助于提高其生存质量并节约医疗成本。本文整理了老年人医疗语篇理解的影响因素,包括加工能力等老年人个体因素和可读性等语篇设计因素,并在此基础上提出了老年人医疗语篇理解补偿模型。该模型尝试阐述上述各影响因素中,那些随龄衰退的因素(如加工能力),如何从别的因素中得到补偿(如医疗知识),从而支撑老年人的医疗语篇理解。补偿模型有利于干预研究的设计,但也还有待更多的实证研究。     

新世纪20年国内结构方程模型方法研究与模型发展

新世纪前20年, 国内结构方程模型(SEM)方法研究主要涉及5个主题：模型发展、参数估计、模型评价、测量不变性及特殊数据处理, 特别是模型发展方面(即SEM的各种变式)有较多成果。对每个主题, 在简述背景知识的基础上, 系统总结了方法学研究发展及成果。最后也讨论了SEM的国外方法学研究进展和未来研究方向。     

Person–organization fit effects on organizational attraction: A test of an expectations-based model

This study investigates the mechanisms that explain why person–organization (PO) fit impacts organizational attraction. Adopting Edwards and Cable’s (2009) approach, an integrative model is developed around the idea that experiencing value congruence during the recruitment process perpetuates certain expectations about future work environments and employer relationships. These expectations in turn have a positive impact on organizational attraction. Evidence from a longitudinal study on a sample of job seekers suggests that expected opportunities for value expression and need fulfillment offered the most viable explanations of value congruence effects. The implications of important observed differences in the experience of PO fit between job seekers and full-time employees are discussed.     

鼻烟窝皮瓣修复拇指大面积皮肤缺损的临床应用

探讨鼻烟窝皮瓣在修复拇指大面积皮肤缺损中的方法和治疗效果。从2008年1月～2013年10月间应用桡动脉在解剖鼻烟窝穿支为血管蒂的鼻烟窝皮瓣,逆行修复拇指大面积皮肤缺损26例,年龄17岁～55岁。术后平均随访时间25个月,皮瓣全部成活。皮瓣色泽及质地与健侧拇指背侧皮肤相近,拇指活动度基本正常。因此,鼻烟窝皮瓣是一种简便经济、效果理想、患者易于接受的术式,适合应用于拇指大面积皮肤缺损的治疗。