This study investigated the effect of isoflavone aglycone (IA) on the learning and memory performance of senescence-accelerated mice, and explored its neural protective mechanism. Results showed that SAM-P/8 senescence-accelerated mice treated with IA performed significantly better in the Y-maze cognitive test than the no treatment control (P<0.05). The cortex AchE activity, serum SOD and GSH-Px activities were notably higher (P<0.05). MDA concentration and the β-secretase activity in the hippocampal tissue were both lower (P<0.05). Additionally, the number of hippocampal neurons was increased and cell morphology was significantly improved. Data suggested that IA could indirectly increase concentration of the cholinergic neural transmitter Ach through regulation of AchE, therefore improving the central cholinergic function and enhancing the learning and memory ability. By reducing the β-secretase activity, IA could decrease the formation and deposition of insoluble Adebris, relieve the resulted toxicity and damage to neurons, and thereby effectively protect the nervous system. 相似文献
Multifunctional products are ubiquitous in consumers' daily lives. However, scant research has examined whether and how the presence of multifunctional products systematically alters consumer behavior beyond product evaluations and adoption. Across four experiments and three supplementary studies, the authors identify a multifunction-impatience effect. They show that after exposure to multifunctional (vs. single-function) products, consumers are more likely to choose a smaller but sooner (vs. a larger but later) reward (Study 1), report more impatience when waiting for the web search results to load and perceive the loading time as longer (Study 2), and are willing to pay more for expedited shipping (Study 3). The authors further show that the effects occur because multifunctional products activate an efficiency goal among consumers, which renders them less patient (studies 2 and 3). In addition to the regular, “sequential” multifunctional products for which each of the functions has a specific usage situation, the proposed effect also applies to “simultaneous” multifunctional products whose functions operate simultaneously during consumption (Study 4). Taken together, this research broadens the scholarly understanding of the effects of multifunctional products from consumers' responses to these products to the unintended impact of such products on consumer impatience. 相似文献
Journal of Child and Family Studies - Drawing on self-determination theory and problem-behavior theory, we tested the relation between parental psychological control and adolescents’... 相似文献
In response to the COVID-19 pandemic, restrictions on economic activities have resulted in a sharp rise of unemployment. The purpose of this research is to explore mental disorders associated with COVID-19 related unemployment using a large, nationally representative dataset, the 2020 COVID-19 Household Pulse Survey. ANOVA with post hoc tests (Tukey HSD) are utilized to reveal the mean difference of mental disorders between various employment status, as well as between reasons of unemployment. Binary logit model is used to investigate the potential effect of different reasons of unemployment on mental disorders. Individuals who were not working during the pandemic due to involuntary reasons had higher probabilities of mental disorders than those who were working and those who voluntarily separated from work. Among respondents who were not working due to COVID-19 related reasons, respondents whose employer went out of business were the most likely to experience mental disorders. Household job uncertainty in the next four weeks positively contributed to mental disorders. Government should consider measures to contain the spread of virous while keeping as many people employed as possible. Government should also consider providing adequate financial and counseling assistance to individuals who are in the greatest need for such support.
The current work sought to test the moderating role of a multicultural ideology on the relationship between categorisation salience and ingroup bias. Accordingly, in one experimental study, we manipulated categorisation salience and the accessibility of a multicultural ideology, and measured intergroup attitudes. Results show that categorisation salience only leads to ingroup bias when a multiculturalism (MC) ideology is not made salient. Thus, MC ideology attenuates the negative effects of categorisation salience on ingroup bias. These results pertain to social psychology in general showing that the cognitive processes should be construed within the framework of ideological contexts. 相似文献